Improved Enamel Remineralisation Using A Novel Biomimetic System
Funder
National Health and Medical Research Council
Funding Amount
$746,581.00
Summary
Tooth decay remains a major public health problem. The project will involve the testing of the system to remineralize (repair) early stages of decay. The project also involves the detailed characterization of the molecular interactions of the components of a system. It is anticipated that this project will result in the development of a system with substantially superior properties for the non-invasive treatment (repair) of early tooth decay.
Determining How Genetic And Environmental Factors Influence The Developing Oral Microbiota And Drive Disease In Early Childhood
Funder
National Health and Medical Research Council
Funding Amount
$397,064.00
Summary
Children’s oral health is in a dire state, with dental decay being the most common chronic disease. We will determine how an individuals’ environment and their genetic makeup drive variation in the composition of the oral microbiota to produce childhood decay, by genetically analysing dental plaque from an Australian twin cohort. Our study will be used to identify high decay risk individuals and direct treatment approaches by discovering anti-decay agents among the oral microbiota.
A Longitudinal Controlled Study To Prevent Early Childhood Caries From Ages 0-6 Years In A Disadvantaged Community In Queensland
Funder
National Health and Medical Research Council
Funding Amount
$695,788.00
Summary
Rampant dental decay in young children is very difficult to prevent. The study will follow a group of high risk children from birth to 6 years of age to test the effectiveness of antibacterial and remineralising agents to prevent dental decay. Our early results showed that these agents have good potential for removing decay-causing bacteria and preventing dental cavities. We expect our long term results will yield valuable information for dental prevention for young children worldwide.
Minimally Invasive Approach To Manage Early Childhood Caries In Aboriginal Preschoolers
Funder
National Health and Medical Research Council
Funding Amount
$1,488,220.00
Summary
The treatment of dental decay in young children is often undertaken in a hospital, which is costly and risky. A treatment approach tested among a non-Aboriginal preschool population in WA, using hand instruments only and without the use of local anaesthesia, showed nearly a ten-fold reduction in the need for specialist dental care. This study will test the effectiveness of dental treatment of preschool children in rural and remote Aboriginal communities, using the alternative approach.
The Aetiology Of Dental Caries - The Role Of Longitudinal Changes In The Oral Microbiome
Funder
National Health and Medical Research Council
Funding Amount
$288,637.00
Summary
This study will examine the association between changes in the composition of the oral bacteria over time and the development and progression of dental decay in Australian children.
Approach To Address Socioeconomic Inequality In Oral Health
Funder
National Health and Medical Research Council
Funding Amount
$773,033.00
Summary
This research program is expected to contribute to filling significant gaps in the understanding of factors determining the oral health of Australian preschool children. The inter-relationship between factors potentially important for child oral health and their effect on oral health will be evaluated. The findings will help to re-evaluate the effectiveness and safety of oral health preventive programs used for children and to explain inequality in oral health of children.
Determinants Of Inequality In Child Oral Health At School Age–A Prospective Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$1,229,853.00
Summary
This study aims to examine effects of socioeconomic circumstances as determinants of child oral health conditions, which can be mediated by dietary patterns, use of fluoride and dental service.
Randomised Control Trial Of Effectiveness Of Silver Fluoride In Managing Deciduous Dental Caries In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$695,220.00
Summary
This study seeks to test a non-invasive treatment for dental decay in young children which may prevent the progression of the decay further into the tooth. This treatment is currently used in some areas. Dental decay is very common in young children in remote communities where access to dental care is often limited. The treatment may reduce pain and oral and facial infections sometimes leading to hospitalisation.
Implementation And Sustainability Of Non-surgical Intervention For Dental Caries In General Dental Practice
Funder
National Health and Medical Research Council
Funding Amount
$390,388.00
Summary
Dentists in NSW and the ACT used new protocols to stop the spread of tooth decay. Many decayed teeth were then remineralised without the use of injections or drilling and filling. The process by which the dentists reorganised their practices to implement the protocols and how they explained them to their patients and practice staff will now be investigated to discover how best to promote their use Australia-wide. The sustainability and cost-effectiveness of this type of care will be measured.
Infant Feeding Including Breastfeeding, And Early Childhood Food And Beverage Intake: Relationships With Early Childhood Caries And Obesity
Funder
National Health and Medical Research Council
Funding Amount
$246,414.00
Summary
Dental decay and obesity in early childhood continues to be a significant health concern in Australian children. Current evidence suggests that these diseases are higher among children in disadvantaged areas. This increases their risk to continue them in adulthood. There is a lack of evidence exploring the interactions between feeding, in particular breastfeeding, obesity, and dental decay. Phase 1 of this study is completed sucessfully. The present proposal is Phase 2 of a longitudinal study th ....Dental decay and obesity in early childhood continues to be a significant health concern in Australian children. Current evidence suggests that these diseases are higher among children in disadvantaged areas. This increases their risk to continue them in adulthood. There is a lack of evidence exploring the interactions between feeding, in particular breastfeeding, obesity, and dental decay. Phase 1 of this study is completed sucessfully. The present proposal is Phase 2 of a longitudinal study that investigates this relationship.Read moreRead less