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Polymer Inclusion Membranes for Electrokinetic Sampling and Separation. This proposal aims to understand the chemical and physical properties governing the transport of ions into and within advanced extracting polymeric materials, known as polymer inclusion membranes, under the influence of an applied voltage. These membranes are dry-to-touch and represent a new and potentially powerful analytical platform for environmental, medical and industry sample preparation. By understanding the transport ....Polymer Inclusion Membranes for Electrokinetic Sampling and Separation. This proposal aims to understand the chemical and physical properties governing the transport of ions into and within advanced extracting polymeric materials, known as polymer inclusion membranes, under the influence of an applied voltage. These membranes are dry-to-touch and represent a new and potentially powerful analytical platform for environmental, medical and industry sample preparation. By understanding the transport mechanism, new membranes will be developed, capable of purifying and concentrating diverse targets chemicals from liquid and solid samples. These processes can take place during sample transportation to a centralised laboratory thus simplifying and streamlining analysis upon arrival to decrease drastically its costs.Read moreRead less
Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge ....Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge regarding the function of the CNS and deliver complex human cellular systems, that have both discovery and commercial applications.
Benefit: These platforms will have subsequent application revealing the mechanisms underlying numerous neurological diseases, with capacity to upscale for rapid drug screening.
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ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre wi ....ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre will accelerate technologies to transfer successful networks into crops and build legal frameworks to secure this knowledge. With a uniquely multidisciplinary team, the Centre will deliver new strategies to address the problems of food security and climate change, establishing Australia as a global leader in these areas.Read moreRead less
The global consequences of subduction zone congestion. This project will use a combination of 3D geodynamic modelling, plate kinematic reconstruction and geological and geophysical synthesis to determine how congested subduction zones influence plate kinematics, subduction dynamics and tectonic evolution at orogen and global scales. The project aims to deliver a transformation change in understanding the links between congested subduction, mantle flow, trench migration, crustal growth, transitio ....The global consequences of subduction zone congestion. This project will use a combination of 3D geodynamic modelling, plate kinematic reconstruction and geological and geophysical synthesis to determine how congested subduction zones influence plate kinematics, subduction dynamics and tectonic evolution at orogen and global scales. The project aims to deliver a transformation change in understanding the links between congested subduction, mantle flow, trench migration, crustal growth, transitions between stable convergent margin configurations and deformation in the overriding plates of subduction zones. Determining these relationships is significant because it will provide dynamic context to interpret the geological record of ancient convergent margins, which host a large percentage of Earth's metal resources.Read moreRead less
Linking wave–sea ice feedbacks to rapid ice retreat. Antarctic sea ice extent has been in sharp decline since 2016, which is stressing the fragile Southern Ocean and Antarctic environments so vital to the global climate. This project aims to investigate a crucial candidate mechanism of sea ice loss by predicting rapid ice retreat in response to large Southern Ocean waves. New theory and modelling capabilities that account for wave–ice feedbacks will underpin the predictions, leveraging on recent ....Linking wave–sea ice feedbacks to rapid ice retreat. Antarctic sea ice extent has been in sharp decline since 2016, which is stressing the fragile Southern Ocean and Antarctic environments so vital to the global climate. This project aims to investigate a crucial candidate mechanism of sea ice loss by predicting rapid ice retreat in response to large Southern Ocean waves. New theory and modelling capabilities that account for wave–ice feedbacks will underpin the predictions, leveraging on recent research breakthroughs, including novel datasets derived from satellite and field observations. The outcomes are expected to quantify sea ice retreat due to ocean waves for the first time, with potentially major implications for coupled wave–sea ice modelling in climate studies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100201
Funder
Australian Research Council
Funding Amount
$530,000.00
Summary
A major upgrade to the Australia Telescope Compact Array. This project aims to upgrade the $150m CSIRO Australia Telescope Compact Array ("the telescope"), by replacing the signal processing electronics and doubling the bandwidth. This will significantly enhance the performance of the telescope, enabling more ambitious science by the 450 researchers and students who use it each year. For example, it will enable the telescope to study radio counterparts to Gravitational Wave sources, and it will ....A major upgrade to the Australia Telescope Compact Array. This project aims to upgrade the $150m CSIRO Australia Telescope Compact Array ("the telescope"), by replacing the signal processing electronics and doubling the bandwidth. This will significantly enhance the performance of the telescope, enabling more ambitious science by the 450 researchers and students who use it each year. For example, it will enable the telescope to study radio counterparts to Gravitational Wave sources, and it will enable it to make detailed observations of initial discoveries made with the Australian Square Kilometre Array Pathfinder and other Australian telescopes. In short, it will enable Australian researchers to do more ambitious research, and make more discoveries, across broad areas of astrophysics.Read moreRead less
Special Research Initiatives - Grant ID: SR200100008
Funder
Australian Research Council
Funding Amount
$20,000,000.00
Summary
The Australian Centre for Excellence in Antarctic Science. The Centre will revolutionise predictions of the future of East Antarctica and the Southern Ocean. Changes in the Antarctic will be profoundly costly to Australia, including sea-level and fisheries impacts; but the speed and scale of future change remains poorly understood. A new national-scale and interdisciplinary Centre is required to understand the complex interactions of the ocean, ice sheets, atmosphere and ecosystems that will gov ....The Australian Centre for Excellence in Antarctic Science. The Centre will revolutionise predictions of the future of East Antarctica and the Southern Ocean. Changes in the Antarctic will be profoundly costly to Australia, including sea-level and fisheries impacts; but the speed and scale of future change remains poorly understood. A new national-scale and interdisciplinary Centre is required to understand the complex interactions of the ocean, ice sheets, atmosphere and ecosystems that will govern Antarctica’s future. The Centre will combine new field data with innovative models to address Australia’s Antarctic science priorities, train graduate students, develop leaders, engage the public, and enable major economic benefit as Australia adapts to climate change in the coming years and beyond.Read moreRead less
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
Exploration targeting from next-generation volcanic facies reconstruction. The project aims to develop new innovative image analysis techniques to reconstruct the architecture of the volcanic host at four highly prospective hydrothermal-magmatic ore deposits, and investigate the properties of rocks that favour high-grade ore mineralisation. Expected outcomes of this project include next-generation automated techniques for volcanic facies analysis, and predictions of where hydrothermal alteration ....Exploration targeting from next-generation volcanic facies reconstruction. The project aims to develop new innovative image analysis techniques to reconstruct the architecture of the volcanic host at four highly prospective hydrothermal-magmatic ore deposits, and investigate the properties of rocks that favour high-grade ore mineralisation. Expected outcomes of this project include next-generation automated techniques for volcanic facies analysis, and predictions of where hydrothermal alteration is most prospective for mineralisation. Both outcomes are relevant to the discovery of volcanic-hosted mineralisation globally. This project will provide significant benefit to the Australian mining industry by diversifying ore exploration strategies in the Australian crust, and will train the next generation of explorers.Read moreRead less
Function and evolution of insect odorant receptors. This project aims to shed light on how insect odorant receptors function by using comparative genomic studies between the genetic model insect Drosophila melanogaster and a pest species, the Australian sheep blowfly. This project expects to generate knowledge of how specific chemicals activate specific receptors in order to excite sensory neurons and drive behaviour, which is not well understood. Expected outcomes include increased understandin ....Function and evolution of insect odorant receptors. This project aims to shed light on how insect odorant receptors function by using comparative genomic studies between the genetic model insect Drosophila melanogaster and a pest species, the Australian sheep blowfly. This project expects to generate knowledge of how specific chemicals activate specific receptors in order to excite sensory neurons and drive behaviour, which is not well understood. Expected outcomes include increased understanding of olfaction in insects, increased national and international collaboration, and outstanding graduate student training. This research will be of significant future benefit in deriving methods to modify the behaviour of insects of agricultural or medical importance, for example the sheep blowfly. Read moreRead less