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Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability t ....Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability through the convergence of expertise and innovation in analytical chemistry, materials science and cellular biology, ultilising the latest technology and understanding of 3D micro/electrofluidics, to enable the study and stimulation of advanced biological models, sustained within precisely controlled 3D micro-environments.Read moreRead less
Understanding the mechanisms underpinning complex sociality. This project aims to investigate the mechanisms underlying the formation of complex social systems in vertebrates. Our understanding of these mechanisms is strongly biased towards a few model systems. We have identified a novel Australian model system with a wide range of sociality for this purpose. This project expects to generate new knowledge on how the social environment interacts with the brain during social organisation. Expected ....Understanding the mechanisms underpinning complex sociality. This project aims to investigate the mechanisms underlying the formation of complex social systems in vertebrates. Our understanding of these mechanisms is strongly biased towards a few model systems. We have identified a novel Australian model system with a wide range of sociality for this purpose. This project expects to generate new knowledge on how the social environment interacts with the brain during social organisation. Expected outcomes include the refinement of social theory and capacity building via international collaboration and postgraduate training. This work will provide significant benefits by increasing our understanding of how the brain and social environment interact to moderate aggression and enhance social associations.Read moreRead less
Changes in the ocean's biological pump: innovative models and diagnostics. This Project aims to quantify how the ocean’s biological pump, which exports newly formed organic matter into the ocean interior, responds to environmental change. The biological pump is a key control on the global carbon and oxygen cycles, and hence on the viability of marine life. New, efficient numerical models will be developed and analysed with highly innovative mathematical methods. Expected outcomes are optimised .... Changes in the ocean's biological pump: innovative models and diagnostics. This Project aims to quantify how the ocean’s biological pump, which exports newly formed organic matter into the ocean interior, responds to environmental change. The biological pump is a key control on the global carbon and oxygen cycles, and hence on the viability of marine life. New, efficient numerical models will be developed and analysed with highly innovative mathematical methods. Expected outcomes are optimised predictive models and a new understanding of the possible future evolutions of the ocean carbon cycle, acidification, and oxygenation. This should provide significant benefits such as predictions of future ocean health, identification of processes that are sensitive to change, and strategies for marine resource management.Read moreRead less
Eruption and disruption: how Earth’s deep interior and surface communicate. Massive volcanic eruptions are a fundamental part of the Earth System, responsible for globally disruptive events, from airspace disturbance, to extinction of the dinosaurs. This project will reveal relationships between hot, deep sources of volcanic material, and the tectonic processes at the Earth's surface. Expected outcomes of this project include assembling an unprecedented set of new observations from underwater vo ....Eruption and disruption: how Earth’s deep interior and surface communicate. Massive volcanic eruptions are a fundamental part of the Earth System, responsible for globally disruptive events, from airspace disturbance, to extinction of the dinosaurs. This project will reveal relationships between hot, deep sources of volcanic material, and the tectonic processes at the Earth's surface. Expected outcomes of this project include assembling an unprecedented set of new observations from underwater volcanoes offshore Eastern Australia, and the development of innovative geodynamic models of how the deep Earth interacts with the surface to form these volcanoes. This will provide significant benefits by advancing our understanding of the deep Earth, and its impact on Earth’s surface, natural hazards, and mineral systems.Read moreRead less
ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre wi ....ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre will accelerate technologies to transfer successful networks into crops and build legal frameworks to secure this knowledge. With a uniquely multidisciplinary team, the Centre will deliver new strategies to address the problems of food security and climate change, establishing Australia as a global leader in these areas.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100201
Funder
Australian Research Council
Funding Amount
$530,000.00
Summary
A major upgrade to the Australia Telescope Compact Array. This project aims to upgrade the $150m CSIRO Australia Telescope Compact Array ("the telescope"), by replacing the signal processing electronics and doubling the bandwidth. This will significantly enhance the performance of the telescope, enabling more ambitious science by the 450 researchers and students who use it each year. For example, it will enable the telescope to study radio counterparts to Gravitational Wave sources, and it will ....A major upgrade to the Australia Telescope Compact Array. This project aims to upgrade the $150m CSIRO Australia Telescope Compact Array ("the telescope"), by replacing the signal processing electronics and doubling the bandwidth. This will significantly enhance the performance of the telescope, enabling more ambitious science by the 450 researchers and students who use it each year. For example, it will enable the telescope to study radio counterparts to Gravitational Wave sources, and it will enable it to make detailed observations of initial discoveries made with the Australian Square Kilometre Array Pathfinder and other Australian telescopes. In short, it will enable Australian researchers to do more ambitious research, and make more discoveries, across broad areas of astrophysics.Read moreRead less
Physics-aware machine learning for data-driven fire risk prediction. The 2019/20 Australian fire season was unprecedented in its extent, impact, and the response of fire agencies. In this project, we aim to answer the question: was the scale of these fires driven by known drivers of fire (drought, weather, fuels and ignitions), or were fundamentally new undescribed processes and phenomena involved? We will accomplish this by developing an innovative, physics-aware machine learning model of fire ....Physics-aware machine learning for data-driven fire risk prediction. The 2019/20 Australian fire season was unprecedented in its extent, impact, and the response of fire agencies. In this project, we aim to answer the question: was the scale of these fires driven by known drivers of fire (drought, weather, fuels and ignitions), or were fundamentally new undescribed processes and phenomena involved? We will accomplish this by developing an innovative, physics-aware machine learning model of fire risk and spread, trained and validated on a two-decade satellite fire record. The predictive ability of the model will be tested on the 2019/20 fire season to determine if novel drivers of fire can be identified, and the model itself will be operationalised into a novel short-to-mid term fire risk prediction tool. Read moreRead less
Special Research Initiatives - Grant ID: SR200100008
Funder
Australian Research Council
Funding Amount
$20,000,000.00
Summary
The Australian Centre for Excellence in Antarctic Science. The Centre will revolutionise predictions of the future of East Antarctica and the Southern Ocean. Changes in the Antarctic will be profoundly costly to Australia, including sea-level and fisheries impacts; but the speed and scale of future change remains poorly understood. A new national-scale and interdisciplinary Centre is required to understand the complex interactions of the ocean, ice sheets, atmosphere and ecosystems that will gov ....The Australian Centre for Excellence in Antarctic Science. The Centre will revolutionise predictions of the future of East Antarctica and the Southern Ocean. Changes in the Antarctic will be profoundly costly to Australia, including sea-level and fisheries impacts; but the speed and scale of future change remains poorly understood. A new national-scale and interdisciplinary Centre is required to understand the complex interactions of the ocean, ice sheets, atmosphere and ecosystems that will govern Antarctica’s future. The Centre will combine new field data with innovative models to address Australia’s Antarctic science priorities, train graduate students, develop leaders, engage the public, and enable major economic benefit as Australia adapts to climate change in the coming years and beyond.Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Metal complexes for sustainable light-driven synthesis. The aim of this project is to use cheap, abundant transition metal ions and visible light to enable challenging synthetic chemical reactions. The significant problems addressed are that most synthetic reactions using visible light currently require expensive precious metals, and fundamental reaction pathways used by Nature remain inaccessible. Both of these problems limit the scope of synthetic applications. The outcomes will be new knowled ....Metal complexes for sustainable light-driven synthesis. The aim of this project is to use cheap, abundant transition metal ions and visible light to enable challenging synthetic chemical reactions. The significant problems addressed are that most synthetic reactions using visible light currently require expensive precious metals, and fundamental reaction pathways used by Nature remain inaccessible. Both of these problems limit the scope of synthetic applications. The outcomes will be new knowledge and sustainable technologies that can better harness visible light for useful synthetic chemistry applications. The benefits will be more efficient and cost-effective routes to valuable molecules ubiquitous in everyday life.Read moreRead less