Clinical Approaches To Preventing Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$463,652.00
Summary
Cardiovascular disease (CVD) is the leading cause of death and disease burden globally. While many new treatments have been discovered in the last few decades to prevent CVD, surveys show many people do not receive these treatments. Dr. Chow is committed to using her skills as a cardiologist and a researcher to bridge this gap. Her program aims to identify novel, simple and scalable approaches to decrease the gap in preventative care and reduce the burden of CVD in Australia and beyond.
Improving Prevention Of Cardiovascualr Disease In High Risk Populations
Funder
National Health and Medical Research Council
Funding Amount
$408,388.00
Summary
Heart attack and stroke are the leading causes of death and disease burden globally. While there are highly effective treatments to prevent cardiovascular disease, surveys in Australia and other parts of the world indicate they are not being taken up. This program of research aims to improve prevention in individuals at high risk of heart attack and stroke by developing and testing strategies to increase the use of effective evidence-based treatment therapies.
I am a cardiologist and epidemiologist whose research focus is on large-scale clinical trials and epidemiological research into the prevention of cardiovascular disease, particularly in relation to treatment strategies for acute coronary syndromes, dyslip
Identification Of Key Enzymes Required For Efficient Post-translational Modification And Multimerisation Of Adiponectin
Funder
National Health and Medical Research Council
Funding Amount
$92,364.00
Summary
Obesity is a major national and global health issue, with 62% of adult Australians being overweight/obese, associated with a number of diseases such as type 2 diabetes and cardiovascular disease. Fat tissue secretes hormones and dysregulation of these hormones contributes to the development of obesity-associated disease. This project aims to define processes governing the secretion of one key hormone and ultimately to identify targets for the treatment of obesity-associated complications.
Monitoring cardiovascular risk is a major part of the clinical workload both in general practice and specialty areas, but it is an under-researched area, reflected in a general lack of evidence based guidelines. My research will evaluate how to optimise the monitoring of cardiovascular risk both before and after starting treatment. By maximising clinical benefits for patients and minimising unnecessary resource use, my research will benefit patients, clinicians and the community at large.
Personalised Exercise As Medicine. Optimising The Prescription To Maximise The Benefit
Funder
National Health and Medical Research Council
Funding Amount
$772,490.00
Summary
Humans have never been less physically active than in contemporary Western society. These studies will provide an evidence-basis to address the inactivity epidemic by laying the foundation for personalised and effective exercise prescriptions, to which people are more likely to adhere.
Better Evidence And New Tools To Improve Health After Surgical Menopause
Funder
National Health and Medical Research Council
Funding Amount
$1,855,260.00
Summary
Surgical menopause is removal of both ovaries before natural menopause. Surgical menopause may have severe adverse health consequences including short-term symptoms and long-term risk of chronic disease, but more information is needed to inform evidence-based care. This study will deliver the best available evidence internationally on the short (up to 5 year) and long (>20 year) consequences of surgical menopause and new tools for clinicians and patients to integrate this evidence into practi ....Surgical menopause is removal of both ovaries before natural menopause. Surgical menopause may have severe adverse health consequences including short-term symptoms and long-term risk of chronic disease, but more information is needed to inform evidence-based care. This study will deliver the best available evidence internationally on the short (up to 5 year) and long (>20 year) consequences of surgical menopause and new tools for clinicians and patients to integrate this evidence into practiceRead moreRead less
Identifying Novel Targets To Treat And Prevent Diabetic Complications
Funder
National Health and Medical Research Council
Funding Amount
$697,209.00
Summary
Diabetes is the leading cause for kidney failure requiring dialysis or transplantation. Diabetic patients also have a higher risk to suffer from heart attacks, stroke and amputations in particular once kidney damage occurs. Current strategies fail to completely protect patients from complications. My research will uncover knowledge gaps in our understanding of diabetes complications, identify new targets ultimately leading to urgently needed more effective treatments and prevention strategies to ....Diabetes is the leading cause for kidney failure requiring dialysis or transplantation. Diabetic patients also have a higher risk to suffer from heart attacks, stroke and amputations in particular once kidney damage occurs. Current strategies fail to completely protect patients from complications. My research will uncover knowledge gaps in our understanding of diabetes complications, identify new targets ultimately leading to urgently needed more effective treatments and prevention strategies to reduce the burden of disease in diabetes.Read moreRead less