Finding New Evidence Based Therapies For Treating Heart Disease And Stimulating Regeneration
Funder
National Health and Medical Research Council
Funding Amount
$11,088,182.00
Summary
Heart disease is the leading cause of death and disability in our society. This interactive team of clinicians and basic scientists will exploit the latest advances in genome technology and stem cell biology to gain greater insights into the genetic basis of heart disease, elucidate the molecular mechanisms of cardiac function and disease and translate these insights into the development of novel therapeutic approaches for the prevention and treatment of heart disease.
Mechanisms And Therapies In Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$8,360,700.00
Summary
Cardiovascular disease (CVD) claims 1 person every 10 min in Australia and causes 1 in 3 deaths worldwide. The molecular and cellular processes underlying atherosclerosis, vascular injury and thrombosis are highly complex and not well understood. A multifaceted approach is needed to effectively address these key challenges. This Program brings together world experts in these areas to interrogate gaps in our basic understanding of CVD, and to develop novel therapies for CVD patients by exploiting ....Cardiovascular disease (CVD) claims 1 person every 10 min in Australia and causes 1 in 3 deaths worldwide. The molecular and cellular processes underlying atherosclerosis, vascular injury and thrombosis are highly complex and not well understood. A multifaceted approach is needed to effectively address these key challenges. This Program brings together world experts in these areas to interrogate gaps in our basic understanding of CVD, and to develop novel therapies for CVD patients by exploiting new knowledge through integrated research.Read moreRead less
Optimising Heart Disease Prevention And Management
Funder
National Health and Medical Research Council
Funding Amount
$4,647,175.00
Summary
As we become older and risk factors such as obesity become more common, our biggest contributor to death and disability, cardiovascular disease (including heart disease), will continue to exert an enormous burden on our health care system and society. We will extend our ground-breaking research on multidisciplinary teams to create new and innovative health care programs to optimise the prevention and management of new heart disease and chronic forms of heart disease.
Atherosclerosis - The Key Roles Of HDL, Cell Cholesterol Metabolism And Vascular Function
Funder
National Health and Medical Research Council
Funding Amount
$7,085,050.00
Summary
Atherosclerosis, an accumulation of cholesterol in the artery wall, is a major cause of illness and premature death worldwide. It is caused by conditions such as low levels of the protective high density lipoproteins (HDLs), diabetes, smoking and abnormal function of arteries, all of which are linked to disorders of cholesterol metabolism. With our expertise in HDLs, cholesterol metabolism and artery function, our research will lead to the development of novel strategies for early detection and ....Atherosclerosis, an accumulation of cholesterol in the artery wall, is a major cause of illness and premature death worldwide. It is caused by conditions such as low levels of the protective high density lipoproteins (HDLs), diabetes, smoking and abnormal function of arteries, all of which are linked to disorders of cholesterol metabolism. With our expertise in HDLs, cholesterol metabolism and artery function, our research will lead to the development of novel strategies for early detection and prevention of atherosclerosis and heart disease.Read moreRead less
MOTOR IMPAIRMENT: Basic And Applied Human Neurophysiology
Funder
National Health and Medical Research Council
Funding Amount
$6,830,980.00
Summary
Motor Impairment results in physical disability in a wide range of debilitating diseases and health conditions. We will conduct a research program that will include both experimental investigations and clinical trials to identify optimal strategies for maximising physical functioning for people with weakness and fatigue, impaired sensation and balance, and contracture. In doing so, our program offers great scope for improving the health and quality of life for millions of Australians and substan ....Motor Impairment results in physical disability in a wide range of debilitating diseases and health conditions. We will conduct a research program that will include both experimental investigations and clinical trials to identify optimal strategies for maximising physical functioning for people with weakness and fatigue, impaired sensation and balance, and contracture. In doing so, our program offers great scope for improving the health and quality of life for millions of Australians and substantially reducing health care costs.Read moreRead less