Data Fusion for Self-Localisation and Team Situational Awareness in Unknown Structured Environments. This research is directed towards improving the operational effectiveness of our defence and civilian first-response-groups, which include the Special Forces, law-enforcement, fire fighting and special emergency services. These groups are highly specialised and have very focused operations which require innovative responses and adaptability. The technologies developed in the course of this projec ....Data Fusion for Self-Localisation and Team Situational Awareness in Unknown Structured Environments. This research is directed towards improving the operational effectiveness of our defence and civilian first-response-groups, which include the Special Forces, law-enforcement, fire fighting and special emergency services. These groups are highly specialised and have very focused operations which require innovative responses and adaptability. The technologies developed in the course of this project will transform the way these agencies conduct their operations and will have a beneficial impact on our quality of life and social order.
The research will also advance the knowledge base in the practical implementation of human localisation systems and provide the enabling mechanism for its adoption into industry.
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Protein degradation in mammals. One mechanism by which the regulation of protein turnover occurs is the balance between the activity of enzymes responsible for the ubiquitination and deubiquitination of target proteins. The majority of targets of this second family of enzymes are unknown. This project proposes a method for the identification of the targets of two specific mammalian deubiquitinating enzymes in order to understand their function and to begin to explore this new research field. ....Protein degradation in mammals. One mechanism by which the regulation of protein turnover occurs is the balance between the activity of enzymes responsible for the ubiquitination and deubiquitination of target proteins. The majority of targets of this second family of enzymes are unknown. This project proposes a method for the identification of the targets of two specific mammalian deubiquitinating enzymes in order to understand their function and to begin to explore this new research field. Knowledge about this new aspect of protein degradation could provide a powerful tool to test the effect of the stabilisation or removal of specific proteins in the cell and also to develop new technologies in protein production.Read moreRead less
Modelling applications of nanomaterials in biology and medicine. This proposal will address fundamental issues related to nanomaterials and their applications in biology and medicine. Accurate mathematical models will be formulated, leading to new practical techniques in nanobiotechnology, safe and effective methods to diagnose and cure diseases including cancer via targeted drug and gene delivery, and detection methods for biological hazards, such as those arising from biological terrorism. The ....Modelling applications of nanomaterials in biology and medicine. This proposal will address fundamental issues related to nanomaterials and their applications in biology and medicine. Accurate mathematical models will be formulated, leading to new practical techniques in nanobiotechnology, safe and effective methods to diagnose and cure diseases including cancer via targeted drug and gene delivery, and detection methods for biological hazards, such as those arising from biological terrorism. The research facility proposed involves significant training of applied mathematicians at honours, PhD and postdoctoral levels and multidisciplinary collaboration, ensuring that Australia maintains and develops an expertise in nanobiotechnology well into the future.Read moreRead less