New clean and green aqueous metathesis. The technique of olefin metathesis has already yielded new pharmaceuticals and materials for use in consumer products and ballistic protection. This project will help move metathesis into the realms of natures aqueous environment, a key advance if metathesis is to reveal its full potential in biological, polymeric, and pharmaceutical applications. We specifically aim to target treatments for cataract (and other conditions associated with an aging populatio ....New clean and green aqueous metathesis. The technique of olefin metathesis has already yielded new pharmaceuticals and materials for use in consumer products and ballistic protection. This project will help move metathesis into the realms of natures aqueous environment, a key advance if metathesis is to reveal its full potential in biological, polymeric, and pharmaceutical applications. We specifically aim to target treatments for cataract (and other conditions associated with an aging population) and also important new biopolymers for use in health technologies of the future.Read moreRead less
Conformationally constrained and immobilized beta-peptides. The research builds on world-class expertise in Australia (particularly Adelaide) in proteomics to provide a basis for fundamental advances in chemistry that will underpin the development of new pharmaceuticals and smart materials, and future technologies and industries. We create a mix of research at the interface of disciplines within academia and industry, with linkages to the very best international researchers and centres. A new cr ....Conformationally constrained and immobilized beta-peptides. The research builds on world-class expertise in Australia (particularly Adelaide) in proteomics to provide a basis for fundamental advances in chemistry that will underpin the development of new pharmaceuticals and smart materials, and future technologies and industries. We create a mix of research at the interface of disciplines within academia and industry, with linkages to the very best international researchers and centres. A new critical mass of expertise in a number of advancing areas of chemistry, biology, and materials science will be introduced to Australia. This will enhance existing strengths and opportunities in proteomics and biomedical research for the treatment of disease.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100010
Funder
Australian Research Council
Funding Amount
$720,000.00
Summary
A 5-D Correlative Imaging Platform: Combining the strengths of light and electron microscopy. This will be Australia's first dedicated five-dimensional multiphoton-microscopy platform, allowing observation of dynamic structures across different length and time scales under controlled temperatures, followed by high-resolution electron microscopy studies on the same samples. This platform will provide a unique characterisation tool to Australia's top-flight investigators, and so contribute to the ....A 5-D Correlative Imaging Platform: Combining the strengths of light and electron microscopy. This will be Australia's first dedicated five-dimensional multiphoton-microscopy platform, allowing observation of dynamic structures across different length and time scales under controlled temperatures, followed by high-resolution electron microscopy studies on the same samples. This platform will provide a unique characterisation tool to Australia's top-flight investigators, and so contribute to the nation's research priorities. It will enable: fundamental studies of cancer, neural diseases and immune disorders; the development of frontier technologies, such as smart nanomaterials, biosensors and targeted drug delivery; and applied research to help plants and soils adapt to climate variability, and to increase sustainable use of water.Read moreRead less