In the Driver's seat: role of trace elements in enabling crustal fluid flow. This proposal aims to systematically investigate the role of trace elements in controlling the kinetics, product composition, and feed-back between fluid flow and the reaction interface, in fluid-driven mineral reactions. This project expects to provide a framework for the integration of activator trace elements in models of crustal fluid flow and their application in the recovery of base, precious, and critical metals, ....In the Driver's seat: role of trace elements in enabling crustal fluid flow. This proposal aims to systematically investigate the role of trace elements in controlling the kinetics, product composition, and feed-back between fluid flow and the reaction interface, in fluid-driven mineral reactions. This project expects to provide a framework for the integration of activator trace elements in models of crustal fluid flow and their application in the recovery of base, precious, and critical metals, using interdisciplinary approaches across geochemistry, mineral engineering and material sciences. Expected outcomes include improved prediction of the transport of metals and fluids in geo-systems. This should provide significant benefits towards integrating the mineral value chain from exploration to mining and metallurgy.Read moreRead less
Where to find giant porphyry and epithermal gold and copper deposits. This project will determine when and where giant gold or copper deposits should form, consolidating links with Indonesia, and using South East Asia as a vast natural laboratory in which to examine the effect of large-scale tectonic processes. The project will produce a four-dimensional virtual exploration toolkit to show how to apply the methods.
Developing a new tectonothermal and mineralization history for the Capricorn Orogen, Western Australia: Assisting mineral exploration in greenfields terrains. Successful exploration models rely on the development of a reliable geological framework through which to understand the specific processes responsible for the formation of economic ore deposits. A framework cannot be constructed without robust age data. This Project will apply advanced geochronology, combined with regional- and deposit-sc ....Developing a new tectonothermal and mineralization history for the Capricorn Orogen, Western Australia: Assisting mineral exploration in greenfields terrains. Successful exploration models rely on the development of a reliable geological framework through which to understand the specific processes responsible for the formation of economic ore deposits. A framework cannot be constructed without robust age data. This Project will apply advanced geochronology, combined with regional- and deposit-scale field mapping, to formulate a new and improved stratigraphic and tectonic framework for a prospective greenfields region in Western Australia. Outcomes from this Project will lead to more effective exploration models and thereby better exploration targeting. Reducing uncertainty and risk in exploration is key to the discovery and development of deep Earth resources. Read moreRead less
Experimental constraints on the genesis of gold-rich ore deposits. The project will provide a new set of tools to explore for gold-rich ore deposits in Australia and globally. By integrating geochemical studies with cutting-edge experiments carried out at three Australian universities in strategic partnership with industry, the outcomes of this project will provide much needed knowledge to predict the locations of large gold-rich deposits that are concealed beneath vast expanses of the Australia ....Experimental constraints on the genesis of gold-rich ore deposits. The project will provide a new set of tools to explore for gold-rich ore deposits in Australia and globally. By integrating geochemical studies with cutting-edge experiments carried out at three Australian universities in strategic partnership with industry, the outcomes of this project will provide much needed knowledge to predict the locations of large gold-rich deposits that are concealed beneath vast expanses of the Australian continent. The new results will translate into smarter exploration practice, significantly enhancing success in targeting ore deposits that are rich in high-value metal and display the smallest have a small environmental footprint, to underpin the sustainability of our nation into the future.
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Role Of Transition Metal Ions And Redox Activity In The Development Of Atherosclerotic Plaques
Funder
National Health and Medical Research Council
Funding Amount
$196,018.00
Summary
Metal ions such as iron and copper have been reproted to be present in the lesions present in diseased human arteries and it has been suggested that these metal ions contribute to the development of atherosclerosis (hardening of the arteries) via their ability to catalyse the formation of highly reactive molecualr fragments called free radicals. Though metal ions are known to catalyse such reactions in test-tube experiments, both the presence of metal ions in diseased arteries and their ability ....Metal ions such as iron and copper have been reproted to be present in the lesions present in diseased human arteries and it has been suggested that these metal ions contribute to the development of atherosclerosis (hardening of the arteries) via their ability to catalyse the formation of highly reactive molecualr fragments called free radicals. Though metal ions are known to catalyse such reactions in test-tube experiments, both the presence of metal ions in diseased arteries and their ability to generate free radicals is controversial. This study will employ a novel, minimally-invasive, technique to assess the nature and quantity of metal ions present in well-defined human and animal lesions at different stages of lesion development. The ability of these metal ions to catalyse free radical formation from components present in the artery wall will also be assessed. The release of these metal ions from the artery wall to added organic molecules will be assessed as this might minimise their potential to cause damage, and provide a possible therapeutic strategy. These studies will therefore provide valuable information as to the significance and role of reactive metal ions in the development of human artery disease and the possible prevention, or minimisation, of such processes.Read moreRead less
Neoproterozoic global geodynamic and climatic events: were they linked? This project will study a unique cluster of global geodynamic and climatic events 850-700 million years ago that will help us to understand the interactions between the Earth's deep mantle, its crust, and its atmospheric climate. Academic values aside, the work will bring direct benefit to the Australian industry. Knowledge on the distribution of the Neoproterozoic plume events will provide new exploration targets for Ni-Cu- ....Neoproterozoic global geodynamic and climatic events: were they linked? This project will study a unique cluster of global geodynamic and climatic events 850-700 million years ago that will help us to understand the interactions between the Earth's deep mantle, its crust, and its atmospheric climate. Academic values aside, the work will bring direct benefit to the Australian industry. Knowledge on the distribution of the Neoproterozoic plume events will provide new exploration targets for Ni-Cu-PGE and V-Ti deposits. Better constrained palaeogeography will help to locate mineral-rich crustal provinces that were once connected. Understanding climatic consequences of global geodynamic events will help to better understand and respond to climate changes. Read moreRead less
Evolution of the Proterozoic lithosphere and its bearing of sediment hosted base metal mineralisation. This project aims to determine the aspects of lithospheric evolution that led to a concentration of giant base metal mineral deposits in the Early to Middle Proterozoic (ca 1.9-1.5 billion years ago). We propose to test three related hypotheses that, if validated, will fundamentally change our view of Proterozoic metallogenesis and the way the mineral industry approaches exploration for these ....Evolution of the Proterozoic lithosphere and its bearing of sediment hosted base metal mineralisation. This project aims to determine the aspects of lithospheric evolution that led to a concentration of giant base metal mineral deposits in the Early to Middle Proterozoic (ca 1.9-1.5 billion years ago). We propose to test three related hypotheses that, if validated, will fundamentally change our view of Proterozoic metallogenesis and the way the mineral industry approaches exploration for these deposits.Read moreRead less
Advanced studies on the hydrometallurgy and electrochemistry of primary copper sulphide ores. The exploitation of low quality copper ores is hampered by our poor understanding of the fundamental chemistry involved. In this project, advanced techniques will be developed to understand the leaching of copper to a level of detail not obtained before. This will allow mining companies to extract copper with minimal environmental footprint.
The Early Stages of Granite Evolution: Extraction and Transport Through Ductile Crust . This research is aimed at understanding how the continents develop through several stages of rock melting. Rock melts deep in the continents to form granite magmas which rise, transporting to the upper crust important metals, such as gold, copper and tin, and heat producing elements such as uranium, thorium and potassium. This research proposal seeks to understand how granite melts form and rise transporting ....The Early Stages of Granite Evolution: Extraction and Transport Through Ductile Crust . This research is aimed at understanding how the continents develop through several stages of rock melting. Rock melts deep in the continents to form granite magmas which rise, transporting to the upper crust important metals, such as gold, copper and tin, and heat producing elements such as uranium, thorium and potassium. This research proposal seeks to understand how granite melts form and rise transporting these all important elements, which control not only our wealth but also the stability of the continents we live in.Read moreRead less
Understanding the Sibao Orogenic Belt in South China: A Part of the Rodinian Supercontinent Assembly Adjacent to Australia. The Sibao Orogenic Belt (SOB) in South China is regarded as one of the worldwide 1300-1000 Ma mountain belts that record the assembly of the supercontinent Rodinia. However, recent work suggests that some of these mountain belts, including the SOB, were probably active until 900 Ma, thus questioning parts of the early Rodinia reconstructions. In this study we aim to deter ....Understanding the Sibao Orogenic Belt in South China: A Part of the Rodinian Supercontinent Assembly Adjacent to Australia. The Sibao Orogenic Belt (SOB) in South China is regarded as one of the worldwide 1300-1000 Ma mountain belts that record the assembly of the supercontinent Rodinia. However, recent work suggests that some of these mountain belts, including the SOB, were probably active until 900 Ma, thus questioning parts of the early Rodinia reconstructions. In this study we aim to determine the ages, and geochemical and structural characteristics of key tectonic units in the SOB. This will lead to a better understanding of the assembly process of Rodinia, and events occurring in continental blocks adjacent to Australia at that time.Read moreRead less