Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critica ....The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critical ecosystem function and community structure across local to global scales, including the identification of non-linearities and interactions involving human effects on this process. This research is expected to safeguard marine ecosystems from collapse.Read moreRead less
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100203
Funder
Australian Research Council
Funding Amount
$385,000.00
Summary
Autonomous benthic observing system. This project seeks to improve our ability to monitor marine habitats and characterise their variability by enhancing the Integrated Marine Observing system (IMOS) Autonomous Underwater Vehicle (AUV) Facility. The new AUV infrastructure will reduce operating costs, increase robustness of the sampling effort and insure continued operation for the next decade.
Coupled physical and biogeochemical dynamics on the Australian North West Shelf. Information regarding the natural function of the Australian North West Shelf is urgently required to sustainably manage the often conflicting uses of the region. This project will study the role of ocean processes in driving ocean productivity on the North West Shelf and determine the impact of projected climate variability.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100219
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate k ....A multi-institutional environmental radioactivity research centre. This project aims to establish an environmental radioactivity research centre, equipped with ultra-low background and high-resolution alpha and gamma spectrometry systems, radon detectors and radium delayed coincidence counters. The centre will address a critical demand in Australia for precise analysis of a large suite of natural and artificial radionuclides, which will be used as tracers and chronological tools to investigate key questions in oceanography and the mining and energy, archaeological, agricultural, and forestry sectors. The facility is expected to substantially increase expertise and training in radionuclides in Australia, and promote high-level research collaborations and outputs of both national and international significance. Major outcomes of the proposed facility include better understanding of how oceans regulate climate and improved capacity to assess effects of radiation on natural ecosystems.Read moreRead less
Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and ....Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and a better understanding of long-run health and inequality. These should provide economic and social benefits by informing policy aimed at contemporary social and health challenges, enhancing our understanding of Australian history, and developing public resources.Read moreRead less
The Courtroom, Lawyers and the Press: Negotiating Justice in the Age of the Public Sphere. The origins of modern Australian systems of justice are derived from institutions and cultures developed in Britain, and this project will contribute a deeper understanding of their nature and provenance. It will illuminate the roots of the modern trial as an instrument of governance that involves largely symbolic, rather than substantive, popular participation, and trace its equally significant role as a ....The Courtroom, Lawyers and the Press: Negotiating Justice in the Age of the Public Sphere. The origins of modern Australian systems of justice are derived from institutions and cultures developed in Britain, and this project will contribute a deeper understanding of their nature and provenance. It will illuminate the roots of the modern trial as an instrument of governance that involves largely symbolic, rather than substantive, popular participation, and trace its equally significant role as a form of popular entertainment. Besides their obvious relevance to questions about active citizenship in modern Australia, scholarly studies of these issues will contribute in a major way to Australia's international reputation for producing high-quality scholarly contributions to British studies.Read moreRead less
Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have change ....Ancient Ecology: Changes in penguin diet over ~30,000 years in Antarctica. This project proposes the first direct study of ancient ecology using a combination of second-generation DNA sequencing and targeted gene recovery. The food web of the Antarctic Ocean is a classic textbook example of energy and nutrient cycling in the marine environment. Although a great deal is known about the current status of this food web, understanding how this complex set of predator / prey relationships have changed over long periods of time is vital to understanding the nature of the system itself. The project intends to track changes in the diet of Adélie penguins from serially preserved ancient fecal (guano) remains dating back approximately 30,000 years. These remains are known to contain microscopic remnants of penguin prey.Read moreRead less
Aboriginalia: Collecting Histories of Aboriginal Representation. Since Federation, non-Indigenous people have produced material objects for the home depicting Aboriginal bodies, artefacts and designs and marketing these as the truly Australian look. Since the 1960s, Aboriginal people started to collect these material objects, defined as 'Aboriginalia'. This interdisciplinary project aims to examine Aboriginal collectors' representations of 'Aboriginalia'. This is the first study to examine Abori ....Aboriginalia: Collecting Histories of Aboriginal Representation. Since Federation, non-Indigenous people have produced material objects for the home depicting Aboriginal bodies, artefacts and designs and marketing these as the truly Australian look. Since the 1960s, Aboriginal people started to collect these material objects, defined as 'Aboriginalia'. This interdisciplinary project aims to examine Aboriginal collectors' representations of 'Aboriginalia'. This is the first study to examine Aboriginal collectors' representations of non-Indigenous historical depictions of Aboriginality within Australian material culture. The research and associated publications will explore the Aboriginal social life of material objects in historical perspective.Read moreRead less