Individualising Care For Patients With Chronic Hepatitis C: Predicting Side Effects And Treatment Response Using Genomic And Proteomic Approaches.
Funder
National Health and Medical Research Council
Funding Amount
$55,575.00
Summary
Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially impro ....Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially improving the safety and efficacy of therapy.Read moreRead less
Developing a Model of ICU Transition Care; Enhancing Services, Enabling Nurses, Empowering Patients. The transition from the Intensive Care Unit (ICU) to the ward is traumatic for patients and families and difficult for ward nurses. Using focus groups and an intervention study, this research will develop and evaluate a model of ICU transition care and demonstrate the extent to which appropriate transition care improves a variety of outcomes for patients, families and staff. We anticipate that t ....Developing a Model of ICU Transition Care; Enhancing Services, Enabling Nurses, Empowering Patients. The transition from the Intensive Care Unit (ICU) to the ward is traumatic for patients and families and difficult for ward nurses. Using focus groups and an intervention study, this research will develop and evaluate a model of ICU transition care and demonstrate the extent to which appropriate transition care improves a variety of outcomes for patients, families and staff. We anticipate that this model will influence practice and policy decisions and be useful in other setting and with other groups who face life transitions such as the military, corrective care and rehabilitation.Read moreRead less
Pathways to healing: determining effective care pathways for chronic wounds for timely healing, prevention and cost effectiveness. Care for chronic leg ulcers is reported to cost 1-2.5% of total health budgets (>3 billion $US/year, $500 million AUD/year). Efficient use of health resources and improved health as a result of effective chronic wound management (early healing and prevention) are the most significant potential outcomes from this study. In addition to direct health care costs, chronic ....Pathways to healing: determining effective care pathways for chronic wounds for timely healing, prevention and cost effectiveness. Care for chronic leg ulcers is reported to cost 1-2.5% of total health budgets (>3 billion $US/year, $500 million AUD/year). Efficient use of health resources and improved health as a result of effective chronic wound management (early healing and prevention) are the most significant potential outcomes from this study. In addition to direct health care costs, chronic wounds are associated with significant hidden burdens on the community resulting from loss of mobility, decreased functional ability, social isolation and loss of participation in the workforce/society. This study will provide much needed information on management of this chronic disease to promote improved quality of life, health and independence in this population.Read moreRead less
Evaluation of treatment outcomes for court-referred and voluntary clients in residential and outclient substance abuse treatment programs. Very little research has been conducted evaluating the relative effectiveness of substance abuse treatment programs for court-referred clients, compared with voluntary clients. This project will obtain psychological, social and health measures in order to compare short- and long-term treatment outcomes. Its significance lies not only in its potential to evalu ....Evaluation of treatment outcomes for court-referred and voluntary clients in residential and outclient substance abuse treatment programs. Very little research has been conducted evaluating the relative effectiveness of substance abuse treatment programs for court-referred clients, compared with voluntary clients. This project will obtain psychological, social and health measures in order to compare short- and long-term treatment outcomes. Its significance lies not only in its potential to evaluate the success of treatment for clients diverted from the criminal justice system, but also in its unique focus on a wide range of outcomes for different client groups.Read moreRead less
A Centre For Research Excellence In Cerebral Palsy (CRE-CP)
Funder
National Health and Medical Research Council
Funding Amount
$2,622,042.00
Summary
Cerebral palsy is the most common physical disability in childhood. Our objective is to bring about a radical improvement in the treatment of individuals with cerebral palsy, both children and adults, and to determine better ways to assist their families. Emphasis will be placed on early detection of health issues and rigorous evaluation of management options. We will train more researchers and ensure that all the knowledge generated is made available to families and health care professionals.
Understanding effective and satisfying communication between health providers and patients and its relationship with health outcomes. This project investigates the components of satisfying and effective consultations for both health professionals and patients, and their relationship with good health outcomes. This project takes an intergroup theoretical perspective to examine interpersonal interactions between health providers and patients. It examines differences in perceptions of role and co ....Understanding effective and satisfying communication between health providers and patients and its relationship with health outcomes. This project investigates the components of satisfying and effective consultations for both health professionals and patients, and their relationship with good health outcomes. This project takes an intergroup theoretical perspective to examine interpersonal interactions between health providers and patients. It examines differences in perceptions of role and communication strategies between in health professionals from different disciplines and between a broad range of patients types.Read moreRead less
Genome-wide Association Study (GWAS) For Juvenile-onset Myopia And Its Component Measures To Identify Molecular Pathways To Prevent Myopia
Funder
National Health and Medical Research Council
Funding Amount
$495,364.00
Summary
We will examine 2,000 young adults from the Western Australian Raine Cohort at the Lions Eye Institute / University of Western Australia. Ocular data will be collected relating to myopia (short-sightedness) and will be combined with extensive previous childhood and genetic research data collected on the Cohort, to investigate the genetic and environmental factors predisposing to myopia. This will assist in understanding the factors leading to myopia.
A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic ev ....A new quality of life instrument with older people for economic evaluation. This project aims to develop and validate a new preference-based quality-of-life instrument with applications in aged-care. The new instrument will be developed with older people receiving aged care services, and will focus upon incorporating their values into the measurement and valuation of quality of life for economic evaluation. The new instrument will have immediate applications in quality assessment and economic evaluation, improving the quality of life and wellbeing of older Australians, and will assist in determining the relative cost effectiveness of new and existing services.
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Harnessing Information Technology To Improve Self-management Behaviours And Health Outcome In People With Heart Failure: A Smarthome Ecosystem Living Lab Study
Funder
National Health and Medical Research Council
Funding Amount
$1,120,226.00
Summary
The burden of heart failure in Australia is substantial. Management of heart failure is complex and requires self-management of symptoms and behaviour change, which requires ongoing education and support to achieve. Current approaches for supporting self-management do not meet the needs of people with heart failure or the healthcare system. This Australian first project aims to co-design an intelligent smart home ecosystem (Smart Heart) to support the management for people with heart failure.
Improving Access To Psychological Services For People With Cancer: A Randomised Control Trial Of An Interactive Web-Based Intervention
Funder
National Health and Medical Research Council
Funding Amount
$612,715.00
Summary
Approximately 35% of people diagnosed with cancer will experience persistent significant distress, and unmet psychological supportive care needs in Australian cancer patients are highly prevalent. The web presents a unique method of delivery of supportive care. However, to our knowledge this type of intervention has not been examined. This two-phased study will develop and test a novel web-based intervention to improve psychological outcomes in cancer patients experiencing distress.