The Implementation And Evaluation Of Living Evidence In The Management Of Chronic Kidney Disease.
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Chronic kidney disease (CKD) is a growing health problem. Improving outcomes for patients with CKD requires the translation of research into clinical care. However, scientific research that underpins the management of CKD has rapidly increased, and traditional methods to summarise and inform clinical care are out of date. This project will develop, evaluate, and implement a new approach, known as ‘living-evidence’, that translates research evidence in real-time into the management of patients.
Discovery Early Career Researcher Award - Grant ID: DE240100260
Funder
Australian Research Council
Funding Amount
$457,378.00
Summary
Refugee moral injury: Linking interpersonal trauma and social functioning. This project aims to understand how moral beliefs about past interpersonal traumatic experiences (e.g., torture, rape) are associated with social outcomes considered to be crucial in successful refugee resettlement. This project will investigate the causal impact of these moral beliefs on social adaptation and whether these beliefs are malleable. The project will be a better understanding of how moral beliefs can impact r ....Refugee moral injury: Linking interpersonal trauma and social functioning. This project aims to understand how moral beliefs about past interpersonal traumatic experiences (e.g., torture, rape) are associated with social outcomes considered to be crucial in successful refugee resettlement. This project will investigate the causal impact of these moral beliefs on social adaptation and whether these beliefs are malleable. The project will be a better understanding of how moral beliefs can impact refugees' abilities to navigate and engage with novel social environments. The outcomes of this project will assist service providers and policy makers to understand why some refugees are able to adapt more successfully than others and provide practical tools for improving social outcomes. Read moreRead less
Promoting Child and Carer Wellbeing and Placement Stability in Kinship Care. Kinship care is the fastest growing out-of-home care placement in Australia, yet least supported. This project aims to implement and evaluate an attachment and trauma-based program for kinship carers, explore its suitability for cultural adaptation for Indigenous families and co-design practical resources to promote program sustainability and trauma-informed practice. This project is Australia’s first randomised trial o ....Promoting Child and Carer Wellbeing and Placement Stability in Kinship Care. Kinship care is the fastest growing out-of-home care placement in Australia, yet least supported. This project aims to implement and evaluate an attachment and trauma-based program for kinship carers, explore its suitability for cultural adaptation for Indigenous families and co-design practical resources to promote program sustainability and trauma-informed practice. This project is Australia’s first randomised trial of a tailored program for kinship carers and expects to generate vital knowledge on evidence-based support. Via implementing an innovative program for kinship carers in statutory child protection, this project should build capacity for research-based practice and benefit family wellbeing and placement outcomes in kinship care.Read moreRead less
Does emotion regulation flexibility improve functioning in refugees? This project aims identify the mechanisms by which low-intensity interventions improve functioning in refugees living in low-and-middle income countries (LMICs). Despite these interventions being implemented with thousands of refugees worldwide, many refugees fail to respond. This project will lead to significant advances in knowledge regarding how and for whom low intensity interventions work. Expected outcomes include enhance ....Does emotion regulation flexibility improve functioning in refugees? This project aims identify the mechanisms by which low-intensity interventions improve functioning in refugees living in low-and-middle income countries (LMICs). Despite these interventions being implemented with thousands of refugees worldwide, many refugees fail to respond. This project will lead to significant advances in knowledge regarding how and for whom low intensity interventions work. Expected outcomes include enhanced capacity of NGOs to deliver effective interventions to refugees living in LMICs, and to tailor their services to those who are at greatest risk of not responding. Benefits include improved functioning of refugees living in LMICs, and enhanced capacity of Australia to meet its international refugee obligations. Read moreRead less
Pathogenic Repeat Expansions In Ataxia: Advancing Gene Discovery And Genetic Diagnosis
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Hereditary ataxia is a severe neurological disorder that results in impaired coordination and balance and affects 1 in 20,000 Australians. Ataxias are often caused by complex genetic mutations called repeat expansions (RE), which are difficult to detect. Therefore, genetic diagnosis of ataxia remains limited and poorly accessible, leading to a gap in clinical care. In this study, we will utilise modern advances in genetic sequencing technology to diagnose and discover ataxias caused by REs.
A Phase III Randomised Placebo-controlled Trial Of Mirtazapine As A Pharmacotherapy For Methamphetamine (Ice) Dependence
Funder
National Health and Medical Research Council
Funding Amount
$3,923,009.00
Summary
Crystalline methamphetamine ('ice') is a growing concern in Australia. There are no approved medications that can be used to treat dependence on this drug. This clinical trial will examine whether mirtazapine, a newly identified treatment agent for methamphetamine use, can be used safely and effectively in routine clinical care to manage methamphetamine dependence in Australia.
Overcoming The Barriers To Treatment Of Multi-drug Resistant Gram-negative Bloodstream Infections In Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$447,603.00
Summary
There is a critical need to develop new treatments for children with antibiotic resistant infections. The most important bacteria causing resistant infections are known as Gram-negative bacteria. Doctors treating children with resistant Gram-negative infections are faced with few antibiotic options. This project will discover the most important resistant infections in Australian children, and trial a new antibiotic to help doctors to use it in the right children and at the right dose.
Whether social media literacy mitigates effects of social media in adolescents. This project aims to determine protective and risk factors for problems associated with social media use in early adolescents. In particular, it aims to determine the protective role of social media literacy (the skill to analyse, critique and evaluate social media posts). Although most Australian adolescents use social media, frequent social media engagement and photo-based activities can cause body dissatisfaction, ....Whether social media literacy mitigates effects of social media in adolescents. This project aims to determine protective and risk factors for problems associated with social media use in early adolescents. In particular, it aims to determine the protective role of social media literacy (the skill to analyse, critique and evaluate social media posts). Although most Australian adolescents use social media, frequent social media engagement and photo-based activities can cause body dissatisfaction, disordered eating and compromised well-being. Findings supporting a protective role for social media literacy are expected to inform policy to improve adolescent well-being and pave the way for school-based social media literacy interventions.Read moreRead less
Creating Treatment Options For Endometrial Cancer Through High-level Clinical Trials
Funder
National Health and Medical Research Council
Funding Amount
$2,508,156.00
Summary
Endometrial cancer (EC) arises from the inner lining of the womb. Treatment typically involves surgery (hysterectomy) to remove the womb and explore if cancer has affected the lymph glands in the pelvis. The benefit of surgery on the lymph glands is doubtful. My research program will generate evidence to inform clinical practice on the treatment of EC and explore non-surgical treatment alternatives to a hysterectomy for better patient outcomes, particularly in women who wish to start a family.
Discovery Early Career Researcher Award - Grant ID: DE210100391
Funder
Australian Research Council
Funding Amount
$418,228.00
Summary
Reducing Gendered Harm in Involuntary Mental Health Service Provision. Involuntary mental health treatment is often traumatising, with women reporting additional gendered dimensions of harm. Using an action research framework that draws upon the voices of service users, families and professionals, this study aims to develop improved strategies for responding to acute mental distress in women, with a focus on reducing coercion. Expected outcomes include enhanced understandings of the experiences ....Reducing Gendered Harm in Involuntary Mental Health Service Provision. Involuntary mental health treatment is often traumatising, with women reporting additional gendered dimensions of harm. Using an action research framework that draws upon the voices of service users, families and professionals, this study aims to develop improved strategies for responding to acute mental distress in women, with a focus on reducing coercion. Expected outcomes include enhanced understandings of the experiences and impacts of compulsory mental health treatment on women and a co-designed online resource that will support the development of effective, realistic and non-coercive practices in frontline mental healthcare. The project will provide substantial benefits to mental health reform at a national and international level.Read moreRead less