Implementation Of A Novel Clinical Pathway Of Care For Common Musculoskeletal Disorders In Primary Care.
Funder
National Health and Medical Research Council
Funding Amount
$1,525,730.00
Summary
This project provides a solution to the burden musculoskeletal disorders in Australia. We will implement a novel clinical pathway of care that uses simple questionnaires to determine whether people will recover simply or require complex care. If simple, we provide people and their healthcare practitioner with guideline-based information developed by our expert team. If complex, we refer them to an expert physiotherapist who can undertake more complex assessments and direct care appropriately.
Is Lactic Acid Concentration In Amniotic Fluid A New Predictor Of Labour Dystocia?
Funder
National Health and Medical Research Council
Funding Amount
$682,538.00
Summary
This study will establish whether higher concentrations of lactate in the amniotic fluid of labouring women can be used as a surrogate marker to improve diagnoses of presence or absence of dystocia. Labour dystocia is a serious problem experienced during childbirth, and is one of the main indications for emergency caesarean section or forceps or vacuum delivery. Although dystocia is a common clinical problem, the current lack of a precise definition leads to considerable variation in practice.
Using Collaboration Networks To Measure Bias And Inefficiency In The Production And Translation Of Evidence About Cardiovascular Risk
Funder
National Health and Medical Research Council
Funding Amount
$219,806.00
Summary
Doctors rely on clinical trials comparing the safety and efficacy of cardiovascular treatments but are often unable to find or trust the information they seek because of problems in evidence translation. This project will examine the networks of collaboration amongst researchers and their research to identify the source of these problems. The research will be used to identify where to intervene in the process, in turn helping doctors to make safe and cost-effective decisions for their patients.
How Can We Accurately Predict Intra-cranial Injury In Children: The APIC Study
Funder
National Health and Medical Research Council
Funding Amount
$836,500.00
Summary
Head injuries are a common in children. Even a seemingly minor incident may cause serious brain injury. Whilst head computed tomography (CT) identifies all important injuries there is a growing recognition that radiation from CTs increases the risk of fatal brain cancers, especially in younger children. This study of 10,000 children with head injuries aims to investigate the best way to accurately predict which children should undergo a head CT, and which children do not require one.
A Randomised Controlled Trial Of Aetiology Based Antiemetic Guidelines For Reducing Nausea In Advanced Cancer Patients.
Funder
National Health and Medical Research Council
Funding Amount
$1,152,116.00
Summary
Nausea is a problem that can be very distressing to patients, and one that is difficult to assess and manage in patients with advanced cancer due to its multiple potential causes for this group. This study aims to test the effectiveness of an intervention which uses available anti-nausea medication specifically targeted to the likely cause of nausea for that individual to reduce the severity and impact of the symptom. It also tests second line medicatioins where nausea is unrelieved.
Glycaemia-increasing Effects Of Sprinting In Type 1 Diabetes: Toward The Validation Of New Clinical Guidelines For Hypoglycaemia Prevention
Funder
National Health and Medical Research Council
Funding Amount
$600,323.00
Summary
Recently, we found that the risk of hypoglycaemia associated with moderate intensity exercise in type 1 diabetic individuals is opposed by one or several short sprints performed during or after exercise. Our goal is to examine if exercising several hours before sprinting decreases its protective effect, and whether sprinting may impair several hours later the counterregulatory responses to hypoglycaemia. Finally, we will determine if guidelines advocating the use of short sprints reduce the risk ....Recently, we found that the risk of hypoglycaemia associated with moderate intensity exercise in type 1 diabetic individuals is opposed by one or several short sprints performed during or after exercise. Our goal is to examine if exercising several hours before sprinting decreases its protective effect, and whether sprinting may impair several hours later the counterregulatory responses to hypoglycaemia. Finally, we will determine if guidelines advocating the use of short sprints reduce the risk of hypoglycaemia under free living conditions.Read moreRead less
Evidence-based Recommendations For Interpregnancy Intervals In High-income Countries
Funder
National Health and Medical Research Council
Funding Amount
$423,305.00
Summary
This study will identify the optimal and harmful interpregnancy intervals for a range of maternal and child outcomes in three high-income countries. With a study population of more than 7.5 million births and a longitudinal study design that matches pregnancies to the same women, this study will inform new interpregnancy interval recommendations for high-income countries that will lead to a reduction in avoidable excess morbidities attributable to uninformed pregnancy planning.
CareTrack Aged: Appropriate Care Delivered To Australians Living In Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$1,157,722.00
Summary
Given Australia’s rapidly ageing population, keeping up with future demands and maintaining quality of care in residential aged care facilities (RACF) is vital. This study will assess whether care delivered is consistent with the evidence in 15 conditions that are frequently managed in RACFs. These will include delirium, dementia, depression, pain management and medication management. We will also assess the quality of life of residents in RACFs.
A Randomised Evaluation Of The Appropriateness Of Anatomic Coronary Investigation In Cardiac Injury/MI Type 2
Funder
National Health and Medical Research Council
Funding Amount
$2,516,561.00
Summary
Myocardial infarction occurring in the context of another concurrent illness is associated with a higher morbidity, and mortality than patients presenting with spontaneous myocardial infarction. Significant variation in the use of coronary angiography for the investigation of these patients exists, and currently no trial evidence or guidelines define best practice. This trial will establish the optimal investigation and treatment approaches for the care of this very common clinical condition.
A Randomised Controlled Trial Of A Web-based, Organisational Systems Change Intervention To Increase Childcare Service Adherence To Dietary Guidelines
Funder
National Health and Medical Research Council
Funding Amount
$1,044,145.00
Summary
To improve children's health, leading health agencies recommend that childcare services provide foods to children consistent with dietary guidelines. The majority of Australian childcare services however do not provide foods that meet these guidelines. Using the highest quality research design, this study will test the effectiveness of a web-based intervention in supporting childcare services to improve the nutritional quality of food provided to children in care.