Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560862
Funder
Australian Research Council
Funding Amount
$546,700.00
Summary
South Australian Facility for Advanced Molecular Imaging. The aim of this project is to establish the South Australian Facility for Advanced Molecular Imaging. The Facility builds on existing expertise and cooperation between the collaborating institutions to expand our capability in advanced analytical confocal microscopy of a wide range of materials from living cells to artificial surfaces. New state-of-the-art microscopes will allow the direct quantitative analysis of molecular interactions w ....South Australian Facility for Advanced Molecular Imaging. The aim of this project is to establish the South Australian Facility for Advanced Molecular Imaging. The Facility builds on existing expertise and cooperation between the collaborating institutions to expand our capability in advanced analytical confocal microscopy of a wide range of materials from living cells to artificial surfaces. New state-of-the-art microscopes will allow the direct quantitative analysis of molecular interactions with high temporal and spatial resolutions. This will advance: understanding the regulation of cellular signalling, gene expression and growth in normal and pathological conditions; development of biosensor technology; and the application of new biomaterials in medicine and industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453839
Funder
Australian Research Council
Funding Amount
$386,892.00
Summary
Adelaide Core Laser Capture Microscopy Facility. Laser Capture Microscopy represents a powerful and essential tool in many aspects of modern cell and molecular biology. Although the applications for these machines are very broad, overall the technology can be viewed as allowing collection of rare cells (or objects as small as bacteria and organelles) from complex tissues and cells. This proposal concerns infrastructure funding to obtain a state-of-the-art core Laser Capture Microscope facility ....Adelaide Core Laser Capture Microscopy Facility. Laser Capture Microscopy represents a powerful and essential tool in many aspects of modern cell and molecular biology. Although the applications for these machines are very broad, overall the technology can be viewed as allowing collection of rare cells (or objects as small as bacteria and organelles) from complex tissues and cells. This proposal concerns infrastructure funding to obtain a state-of-the-art core Laser Capture Microscope facility in Adelaide that will significantly enhance scientific progress in a diverse range of areas including functional genomics of animal, plant and prokaryotic cells.Read moreRead less
Structural and functional characterisation of PI3Kgamma, uniquely activated by p101. The movement of cells is involved in all aspects of life including development, growth and maintenance of organisms. In spite of this, our understanding of the mechanism involved in cell migration is limited. There are a number of conditions in which the ability to control cell movement would be of significant benefit. Examples include autoimmune conditions, asthma and cancer, the social and economic burdens ....Structural and functional characterisation of PI3Kgamma, uniquely activated by p101. The movement of cells is involved in all aspects of life including development, growth and maintenance of organisms. In spite of this, our understanding of the mechanism involved in cell migration is limited. There are a number of conditions in which the ability to control cell movement would be of significant benefit. Examples include autoimmune conditions, asthma and cancer, the social and economic burdens of which account for billions of dollars and millions of Australians. This project aims to understand one of the major mechanisms that controls cell migration, which is expected to produce significant economic and social outcomes in the areas of basic science knowledge, human health, and biotechnology. Read moreRead less