A Study Of Mechanisms Of Cognitive Decline In Type 2 Diabetes Mellitus
Funder
National Health and Medical Research Council
Funding Amount
$510,222.00
Summary
Diabetes mellitus and dementia are major public health problems. Diabetes may increase the risk of dementia. This study aims to uncover the mechanism by which diabetes may increase dementia risk. This may lead to finding new ways to prevent or treat diabetes-related dementia and thus reduce the public health burden of dementia.
Type 2 Diabetes Mellitus And Cognitive Decline - A Longitudinal Study Of Effects And Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$1,317,589.00
Summary
Diabetes mellitus and dementia are major public health problems. Diabetes may increase the risk of dementia. This longitudinal study aims to uncover the mechanism by which diabetes may increase dementia risk. This may lead to finding new ways to prevent or treat diabetes-related dementia and thus reduce the public health burden of dementia.
A Population-based Study Of Cerebrovascular Mechanisms Underyling Gait, Balance And Cognition In Older People
Funder
National Health and Medical Research Council
Funding Amount
$528,330.00
Summary
Mobility problems, falls and dementia are among the major problems affecting older Australians with significant consequent disability. Treatment of such disorders carries an estimated annual cost of around 4 billion dollars. This study will examine the role of age-related brain changes in causing problems with walking, balance and cognitive abilities in the general community. The clarification of the role of the ageing brain in causing such disorders will guide efforts directed at preventing the ....Mobility problems, falls and dementia are among the major problems affecting older Australians with significant consequent disability. Treatment of such disorders carries an estimated annual cost of around 4 billion dollars. This study will examine the role of age-related brain changes in causing problems with walking, balance and cognitive abilities in the general community. The clarification of the role of the ageing brain in causing such disorders will guide efforts directed at preventing the occurrence of falls and dementia.Read moreRead less
Graves’ disease is the most common cause of hyperthyroidism. It leads to long-term impairments in quality of life and has a 40% higher mortality rate compared with the general population. We know surprisingly little about the causes of Graves’ disease. One possible trigger is stressful life events; however, the relationship is yet to be proven. This study will assess whether stressful life events, specifically military deployment, are associated with Graves’ disease.
AusDiab 3: Emerging Risk Factors For And Long-term Incidence Of Cardio-metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,616,397.00
Summary
This study will track 11,000 Australian adults over 12 years to determine how many develop diabetes, obesity, kidney and heart disease. The study will develop ways to best predict those who are going to develop these conditions before they have arisen, and will explore a range of novel risk factors to better understand these conditions.
Optimising Large-scale Public Health Interventions To Control Neglected Tropical Diseases
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Neglected tropical diseases (NTD) are a group of health conditions that affect the poorest of the poor, particularly in remote and rural areas. They affect the most vulnerable communities and cause substantial, chronic health harms impairing personal and social development. Several debilitating NTD are common in remote indigenous communities and Pacific islands. I propose a series of studies to investigate new strategies to control NTD in large populations where these diseases are endemic.
Development Of Early Warning Systems For Dengue Fever Based On Socio-ecological Factors
Funder
National Health and Medical Research Council
Funding Amount
$327,402.00
Summary
Global climate change has potentially serious effects on the transmission of dengue. An early warning system (EWS) based on socio-ecological factors will be developed to examine where and when outbreaks of dengue are likely to occur and how the future dengue control strategies and prevention efforts need to be applied and strengthened in Australia. This project will provide a platform for future research on developing and implementing an EWS for dengue in the Asia-Pacific region.
Exploiting Existing Data Sources To Improve The Prevention And Treatment Of Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$772,490.00
Summary
My program of research exploits several large databases to answer important issues in the prevention and treatment of cardiovascular disease (CVD), which makes a huge contribution to the burden of illness and premature mortality in Australia. An underlying aim is to provide the evidence base to facilitate improvement of the existing CVD risk assessment guidelines in Australia, for better targeting of clinical advice and treatment.
Although the major risk factors for cardiovascular diseases have been known for decades, and modern-day treatment is much advanced, the importance of these diseases persists, such that they remain the number one killer in Australia. This suggests that more can be done to correctly identify those at high and moderate risk of future disease, so as to optimize advice and medical treatment. This project will use the best evidence available to develop new methods of risk prediction and prevention.