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Current Selection
Scheme : Discovery Projects
Socio-Economic Objective : Other
Research Topic : CELLULAR INTERACTION
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Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) (4)
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  • Researchers (70)
  • Funded Activities (8)
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  • Funded Activity

    Discovery Projects - Grant ID: DP0877964

    Funder
    Australian Research Council
    Funding Amount
    $280,000.00
    Summary
    Facilitating intuitive interaction with complex devices for older users. Poorly designed interfaces impact more strongly on older people. Helping designers to make more intuitive interfaces for older community members has great potential for improving their lives and health, and thus benefiting the community generally. Making modern devices easier for older people to use will allow them to participate more fully in society and/or the workplace. This will also help to prevent them from becoming i .... Facilitating intuitive interaction with complex devices for older users. Poorly designed interfaces impact more strongly on older people. Helping designers to make more intuitive interfaces for older community members has great potential for improving their lives and health, and thus benefiting the community generally. Making modern devices easier for older people to use will allow them to participate more fully in society and/or the workplace. This will also help to prevent them from becoming isolated and possibly depressed. This project will apply intuitive interaction to healthcare devices that older people use, which can save costly mistakes and even lives.
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    Funded Activity

    Discovery Projects - Grant ID: DP0773107

    Funder
    Australian Research Council
    Funding Amount
    $255,000.00
    Summary
    Gesture-controlled interaction to enrich information access. This project is a study of gestural computing (enabled by sensors such as pressure mats, infra-red sensors and video tracking) which aims to move away from desk-bound, restrictive computing environments and towards computing that is more integral to the building structure and space itself. Linking gesture controllers and information sonification delivers a unique bridge between data and human interaction. Enriching the capacity to acce .... Gesture-controlled interaction to enrich information access. This project is a study of gestural computing (enabled by sensors such as pressure mats, infra-red sensors and video tracking) which aims to move away from desk-bound, restrictive computing environments and towards computing that is more integral to the building structure and space itself. Linking gesture controllers and information sonification delivers a unique bridge between data and human interaction. Enriching the capacity to access information in dense workplace environments is central to improved efficiency across the Australian workforce. Greater accuracy and enhanced techniques for controlling information in visually-overloaded work environments contribute to Australia's competitive leadership in a global marketplace.
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    Funded Activity

    Discovery Projects - Grant ID: DP0559885

    Funder
    Australian Research Council
    Funding Amount
    $515,000.00
    Summary
    Situated Design Computing: A New Paradigm to Support Design Using Situated Reasoning. A country like Australia with its twin disadvantages of distance from its large markets and small population as its own market has to found its goals in its wealth production on its ability to compete at the high value-adding loci of the economy. Design is a precursor to superior products and is one of the nation's high value-adding wealth generating activities. This project aims to lay the foundations for a .... Situated Design Computing: A New Paradigm to Support Design Using Situated Reasoning. A country like Australia with its twin disadvantages of distance from its large markets and small population as its own market has to found its goals in its wealth production on its ability to compete at the high value-adding loci of the economy. Design is a precursor to superior products and is one of the nation's high value-adding wealth generating activities. This project aims to lay the foundations for a new class of design support tools that have the capacity to be used at a variety of stages in the design process including those stages where major decisions are being taken. This will have the potential to improve the efficacy and the efficiency of Australian design and hence make it more globally competitive.
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    Funded Activity

    Discovery Projects - Grant ID: DP0557863

    Funder
    Australian Research Council
    Funding Amount
    $260,000.00
    Summary
    Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs. The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types o .... Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs. The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types of tissues being generated for clinical applications, including possible applications in the treatment of heart disease, the largest killer of people in the Western world.
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    Funded Activity

    Discovery Projects - Grant ID: DP0880920

    Funder
    Australian Research Council
    Funding Amount
    $259,000.00
    Summary
    Coordination and communication in critical care: Assessing potential technology support. This project will examine temporal coordination demands of busy critical care environments, with the goal of developing better models and tools for evaluating the impact of information and communication technology (ICT) innovation. Millions of dollars can be wasted on healthcare ICT updates when the nature of critical care work, the means of communication, and temporal coordination demands are not fully unde .... Coordination and communication in critical care: Assessing potential technology support. This project will examine temporal coordination demands of busy critical care environments, with the goal of developing better models and tools for evaluating the impact of information and communication technology (ICT) innovation. Millions of dollars can be wasted on healthcare ICT updates when the nature of critical care work, the means of communication, and temporal coordination demands are not fully understood. The outcome of this project will be better conceptual and computational tools for assessing the impact of ICT innovation on safety-critical systems such as healthcare, so providing more cost-effective ICT solutions where there is rapidly-evolving ICT innovation.
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    Funded Activity

    Discovery Projects - Grant ID: DP0557495

    Funder
    Australian Research Council
    Funding Amount
    $425,000.00
    Summary
    Characterization and optimisation of Myomatrix: A novel extracellular matrix hydrogel from muscle. This project would have several sources of benefit for the community. Foremost we will have produced a product that will have a strong commercial application in several fields including basic science and bioengineering. If its full potential were achieved, the development of this innovative new hydrogel would strengthen Australia's standing in the biotechnology field and also enrich specific applic .... Characterization and optimisation of Myomatrix: A novel extracellular matrix hydrogel from muscle. This project would have several sources of benefit for the community. Foremost we will have produced a product that will have a strong commercial application in several fields including basic science and bioengineering. If its full potential were achieved, the development of this innovative new hydrogel would strengthen Australia's standing in the biotechnology field and also enrich specific applications. The knowledge gained from the characterization of this product could also be of benefit to several areas including chemical engineering, tissue engineering, tissue repair, polymer chemistry and food manufacture. The expertise generated and the possibility of collaboration, both academic and with industry would also benefit the community.
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    Funded Activity

    Discovery Projects - Grant ID: DP0665069

    Funder
    Australian Research Council
    Funding Amount
    $229,000.00
    Summary
    Predicting cell wall mechanics from structure in a materials engineering approach to plant growth. The project fosters a novel, interdisciplinary approach to understanding how the structure of plant cell walls determines their mechanical properties. Such understanding requires combining biological and engineering approaches and will illuminate how plants grow and produce cells and organs with particular shapes. This is scientifically important but is also important for industries depending on sp .... Predicting cell wall mechanics from structure in a materials engineering approach to plant growth. The project fosters a novel, interdisciplinary approach to understanding how the structure of plant cell walls determines their mechanical properties. Such understanding requires combining biological and engineering approaches and will illuminate how plants grow and produce cells and organs with particular shapes. This is scientifically important but is also important for industries depending on specialised cell shapes such as those of cotton and wood fibres. Our work will improve our understanding of how wall structure determines fibre and other cell shapes and give us tools which can be used to understand how final wall structure determines the fibre mechanics on which industrial users depend.
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    Funded Activity

    Discovery Projects - Grant ID: DP0343693

    Funder
    Australian Research Council
    Funding Amount
    $270,000.00
    Summary
    Proteomic and Transcriptional Profiling of Cartilage. Gene expression and signalling pathways that regulate cartilage formation, and its orderly transition to bone, are poorly described. Our studies will, for the first time, combine two complementary cutting-edge approaches, protein identification by proteomic analysis, and mRNA profiling by microarray analysis, to define these pathways and develop a comprehensive catalogue of proteins and gene expression patterns during cartilage development a .... Proteomic and Transcriptional Profiling of Cartilage. Gene expression and signalling pathways that regulate cartilage formation, and its orderly transition to bone, are poorly described. Our studies will, for the first time, combine two complementary cutting-edge approaches, protein identification by proteomic analysis, and mRNA profiling by microarray analysis, to define these pathways and develop a comprehensive catalogue of proteins and gene expression patterns during cartilage development and bone formation. This information will provide insight into the regulation of cartilage differentiation, maturation and structure, and will provide a critical platform for the development of more sophisticated cartilage and bone biomaterials for improved tissue repair and regeneration.
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