Isolation and analysis of novel caspases. Apoptosis is an evolutionarily conserved cellular process which must be tightly controlled for normal development and to avoid disease. Rapid progress has been made recently in the elucidation of apoptotic pathways, but many important components are likely still unknown. The caspases constitute the effector arm of apoptotic signalling pathways and some members play important roles in cytokine maturation. We aim to identify novel caspases using an innovat ....Isolation and analysis of novel caspases. Apoptosis is an evolutionarily conserved cellular process which must be tightly controlled for normal development and to avoid disease. Rapid progress has been made recently in the elucidation of apoptotic pathways, but many important components are likely still unknown. The caspases constitute the effector arm of apoptotic signalling pathways and some members play important roles in cytokine maturation. We aim to identify novel caspases using an innovative technique, and to characterise their function and regulation. Molecules identified in this project may be candidate targets for therapies which modulate apoptosis for treatment or prevention of disease, or diagnostic reagent development.Read moreRead less
Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food proces ....Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food processing and cosmetic industries. Successful completion of the project can also strengthen our capacity to participate in new areas of research and positioning Australia at the forefront of bionanotechnology.Read moreRead less
Immigration and parenting among Cambodian and Iraqi women in Australia. Immigration will continue to contribute to Australia's social, cultural and economic fabric. By provide immigrant women with the opportunity to articulate their lived experiences as immigrants and mothers, this study will contribute to our understanding of ways to enhance their social inclusion and resilience. By identifying ways to support newly settled women and their families, the study will contribute to policies and pro ....Immigration and parenting among Cambodian and Iraqi women in Australia. Immigration will continue to contribute to Australia's social, cultural and economic fabric. By provide immigrant women with the opportunity to articulate their lived experiences as immigrants and mothers, this study will contribute to our understanding of ways to enhance their social inclusion and resilience. By identifying ways to support newly settled women and their families, the study will contribute to policies and programs, ensuring a healthy start to life for their children and promoting and maintaining their health, with economic and social benefits to Australia as a whole.Read moreRead less
The Awakening of Faith and New Confucian Philosophy. This project aims to provide a new understanding of how New Confucian philosophy was constructed in modern China. It proposes to debunk the prevailing myth that modern Chinese philosophy owes its identity as a continuation of Confucianism, to the exclusion of the fundamentally ‘foreign’ influence of Buddhism. It is anticipated that this project will substantially advance the knowledge base of Chinese philosophy both in Australia and internatio ....The Awakening of Faith and New Confucian Philosophy. This project aims to provide a new understanding of how New Confucian philosophy was constructed in modern China. It proposes to debunk the prevailing myth that modern Chinese philosophy owes its identity as a continuation of Confucianism, to the exclusion of the fundamentally ‘foreign’ influence of Buddhism. It is anticipated that this project will substantially advance the knowledge base of Chinese philosophy both in Australia and internationally, and will also contribute to a more informed understanding of the philosophical and religious traditions our neighbours use to define national and cultural identity.Read moreRead less
Racial Classifications in Transnational Context: Aborigines and Islanders in Australia, Native Americans, African Americans and Afro-Brazilians. This ongoing project seeks to develop a new and more powerful scholarly paradigm for understanding race through a comparative historical study designed to identify features which are common to concepts of race as they have emerged and shifted in the different societies studied, and to distinguish these from features which are specific to particular soc ....Racial Classifications in Transnational Context: Aborigines and Islanders in Australia, Native Americans, African Americans and Afro-Brazilians. This ongoing project seeks to develop a new and more powerful scholarly paradigm for understanding race through a comparative historical study designed to identify features which are common to concepts of race as they have emerged and shifted in the different societies studied, and to distinguish these from features which are specific to particular societies and/or eras. In addition to developing and demonstrating the approach, the project will reanalyse the racialisation of the four colonised groups, each of which have figured centrally in studies of race. One monograph and at least three major journal articles will result.Read moreRead less
Continuities and change in the history of European women's letter-writing. This project will enhance Australia's strong international reputation for cutting-edge work in European history. At a time when questions about communication, self-representation and personal life are of such very great interest, both academically and more generally, this project offers the possibility of bringing academic scholarship closer to issues that are of general interest to the wider community. There is also cons ....Continuities and change in the history of European women's letter-writing. This project will enhance Australia's strong international reputation for cutting-edge work in European history. At a time when questions about communication, self-representation and personal life are of such very great interest, both academically and more generally, this project offers the possibility of bringing academic scholarship closer to issues that are of general interest to the wider community. There is also considerable national benefit in the innovative approach that this project proposes, which offers a new model for collaborative research in the humanities.Read moreRead less
Toward a Female Stoic Tradition: Women's Writings in England, 1600-1800. This project aims to investigate the neglected history of women’s engagement with Stoic ideas in early modern England. It expects to generate new knowledge of a distinctive strand of women’s Stoic thought by taking a novel interdisciplinary approach to different genres of early modern writing. The intended outcomes include a new understanding of women’s valuable contributions to philosophy, literature, and politics in the p ....Toward a Female Stoic Tradition: Women's Writings in England, 1600-1800. This project aims to investigate the neglected history of women’s engagement with Stoic ideas in early modern England. It expects to generate new knowledge of a distinctive strand of women’s Stoic thought by taking a novel interdisciplinary approach to different genres of early modern writing. The intended outcomes include a new understanding of women’s valuable contributions to philosophy, literature, and politics in the period, as well as a greater appreciation of the gender-inclusivity of Stoic philosophy. This should provide significant benefits, such as the development of Stoic therapeutic techniques informed by women’s experiences, and the promotion of gender equality through the recognition of women’s intellectual history.Read moreRead less
Sexual well-being and ageing: a study of older Australian women. This research addresses important issues of ageism and sexism that together affect older women's health and well-being. The findings will inform the link between aging, sexuality and more general dimensions of health and well-being and advance our understanding of issues central to policy and services for older Australians.
Improving Australia's response to childhood obesity: prevention education and its impact on mothers and families. This project will generate new and more considered approaches to childhood obesity prevention, and in turn ensure future investment of public funds in this area best supports children's health.
Mapping the connectome that controls blood pressure. The connections that an individual brain cell receives from other cells ultimately determines its behaviour. Using a revolutionary new technique, the project will create a map of the brain cells that control blood pressure.