The role of the Ttyh1 protein in cell activation. We have cloned TTYH1, a human homologue of the Drosophila melanogaster tweety gene. The mouse gene has also been identified. The predicted structure of the protein is a membrane protein with 5 transmembrane domains. We have also expressed a GFP-tagged fusion protein in mouse fibroblasts. Confocal microscopy indicates that this protein is likely to be a novel adhesion molecule, with a cellular distribution characteristic of molecules such as integ ....The role of the Ttyh1 protein in cell activation. We have cloned TTYH1, a human homologue of the Drosophila melanogaster tweety gene. The mouse gene has also been identified. The predicted structure of the protein is a membrane protein with 5 transmembrane domains. We have also expressed a GFP-tagged fusion protein in mouse fibroblasts. Confocal microscopy indicates that this protein is likely to be a novel adhesion molecule, with a cellular distribution characteristic of molecules such as integrins. We aim to determine the function of Ttyh1, its interacting intra- and extra-cellular proteins and to assess its candidature as a molecule of importance in cell migration and adhesion.Read moreRead less
Trends in Time: Work, Family and Social Policy in Australia 1992-2006. This project will contribute to the national priority goal of 'strengthening Australia's social and economic fabric to help families and individuals live healthy, productive, and fulfilling lives', within the National Research Priority of 'promoting good health and well being for all Australians'. It will provide sound new evidence for effective strategies fostering the policy goals of reducing stress on families, maintaining ....Trends in Time: Work, Family and Social Policy in Australia 1992-2006. This project will contribute to the national priority goal of 'strengthening Australia's social and economic fabric to help families and individuals live healthy, productive, and fulfilling lives', within the National Research Priority of 'promoting good health and well being for all Australians'. It will provide sound new evidence for effective strategies fostering the policy goals of reducing stress on families, maintaining fertility and encouraging women into paid work. Identifying measures that most support men and women to balance work-family commitments, to spend adequate time with their children and social networks, and most facilitate female workforce participation, will promote national wellbeing. Read moreRead less
Reducing health disparities for older LGBTI Australians. Reducing health disparities for older LGBTI Australians. This project aims to optimise health and aged care services throughout Australia, by bringing together researchers and key organisations in the health, aged, and lesbian, gay, bisexual, transgender and intersex (LGBTI) sectors to build a much-needed evidence base. Older LGBTI Australians have vastly poorer health outcomes than the broader population. This project will provide detaile ....Reducing health disparities for older LGBTI Australians. Reducing health disparities for older LGBTI Australians. This project aims to optimise health and aged care services throughout Australia, by bringing together researchers and key organisations in the health, aged, and lesbian, gay, bisexual, transgender and intersex (LGBTI) sectors to build a much-needed evidence base. Older LGBTI Australians have vastly poorer health outcomes than the broader population. This project will provide detailed quantitative and qualitative data on the challenges and needs of older LGBTI Australians and service providers, and develop essential resources so policymakers and service providers can reduce older LGBTI Australians’ health disparities.Read moreRead less
Completing the Gallipoli story: Researching Turkish Archives for a More Comprehensive History. Both Australia and Turkey see the Gallipoli Campaign as a defining event. Australian perceptions of the Campaign are based on C.E.W. Bean's Official History and a number of popular publications. Yet, despite the vast collection of material held in Turkish archives, existing accounts give scant attention to Turkish operations leaving the story incomplete. This project will rectify that imbalance by loca ....Completing the Gallipoli story: Researching Turkish Archives for a More Comprehensive History. Both Australia and Turkey see the Gallipoli Campaign as a defining event. Australian perceptions of the Campaign are based on C.E.W. Bean's Official History and a number of popular publications. Yet, despite the vast collection of material held in Turkish archives, existing accounts give scant attention to Turkish operations leaving the story incomplete. This project will rectify that imbalance by locating and translating key documents-battlefield reports and signals, War Ministry communications, records of prisoner interrogations, aircraft logs and diaries. The result will be a comprehensive history that will contribute to the deepening relationship between Australia and Turkey as we approach the centenary of the Campaign. Read moreRead less
Work, care, retirement and health: ageing agendas. This project will undertake a gendered analysis of how Australians can retire well, taking account of their key resources (such as work, superannuation, the aged pension, and other assets) and key demands (such as to work longer and to care for others in the context of an ageing population and a more feminised workforce).
The Impact of the Mobile Phone on Work/Life Balance. The telecommuncations industry exemplifies the frontier technologies that are at the heart of Australia's successful knowledge economy. Mobile phones are developing innovative capacities far ahead of consumer needs and requirments. For example, third generation technologies are currently seeking to find the 'killer application' that will provide them with a mass market. A profound understanding of the social dimensions of existing mobile telec ....The Impact of the Mobile Phone on Work/Life Balance. The telecommuncations industry exemplifies the frontier technologies that are at the heart of Australia's successful knowledge economy. Mobile phones are developing innovative capacities far ahead of consumer needs and requirments. For example, third generation technologies are currently seeking to find the 'killer application' that will provide them with a mass market. A profound understanding of the social dimensions of existing mobile telecommunications will provide insights for the development of new technologies and new services. It will provide the industry with a competitive advantage in a fast developing sector.Read moreRead less
Tailoring cellulose properties by manipulating cellulose synthase. Cellulose, a highly abundant polymer produced by plants, has many existing uses in Australian fibre and polymer industries and potential uses as, for example, an abundant feedstuff for biomass conversion into ethanol and other high value products. The optimal properties for different applications vary so that, for example, high crystallinity cellulose gives strong fibres whereas low crystallinity cellulose dissolves in gentler so ....Tailoring cellulose properties by manipulating cellulose synthase. Cellulose, a highly abundant polymer produced by plants, has many existing uses in Australian fibre and polymer industries and potential uses as, for example, an abundant feedstuff for biomass conversion into ethanol and other high value products. The optimal properties for different applications vary so that, for example, high crystallinity cellulose gives strong fibres whereas low crystallinity cellulose dissolves in gentler solvents on the way to producing cellulose-based polymers. By exploring ways to adjust the properties of celluloses for use in different applications, we can deliver potential benefits to primary producers, industries and the environment.
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Australia's Post World War II War Crimes Trials: A systemic and comprehensive Law Reports Series. The publication of the project's Law Reports Series will, in effect, constitute the official history of this extensive Australian war crimes trial experience - in itself, an important national benefit. However, ready access to the previously buried historical primary source material also has profound potential for contemporary application. The proliferation of new international criminal tribunals ....Australia's Post World War II War Crimes Trials: A systemic and comprehensive Law Reports Series. The publication of the project's Law Reports Series will, in effect, constitute the official history of this extensive Australian war crimes trial experience - in itself, an important national benefit. However, ready access to the previously buried historical primary source material also has profound potential for contemporary application. The proliferation of new international criminal tribunals with a concomitant explosion of case law has created a hunger for access to past judicial precedent. Reliance on the results of this project in war crimes trials around the world is guaranteed.Read moreRead less
The human elements: a cultural history of Australian weather. This project will study the experience of weather in Australia from the 1880s to the 1980s. Drawing upon environmental history, history of science and cultural history, we aim to go beyond a catalogue of weather events or climatic obsessions, to explore how the meanings of weather and climate are themselves constructed through the interaction of science, nature and society. This project uses a series of case studies to explore what is ....The human elements: a cultural history of Australian weather. This project will study the experience of weather in Australia from the 1880s to the 1980s. Drawing upon environmental history, history of science and cultural history, we aim to go beyond a catalogue of weather events or climatic obsessions, to explore how the meanings of weather and climate are themselves constructed through the interaction of science, nature and society. This project uses a series of case studies to explore what is human in the elements. The outcomes will include a book, two Metarch publications, collection development and an exhibition brief for the NMA, and web-materials for both industry partners.Read moreRead less
Discovery of new genes for plant cellulose biosynthesis and improved fibre production. Cellulose, the world's most abundant biopolymer, is important to the cotton and forest industries and for human and animal nutrition. Before biotechnology can manipulate cellulose, we must identify the enzymes of the synthesis pathway and understand how their properties determine the properties of the cellulose they produce. Not all enzymes are known and any relationships to cellulose properties remain unexplo ....Discovery of new genes for plant cellulose biosynthesis and improved fibre production. Cellulose, the world's most abundant biopolymer, is important to the cotton and forest industries and for human and animal nutrition. Before biotechnology can manipulate cellulose, we must identify the enzymes of the synthesis pathway and understand how their properties determine the properties of the cellulose they produce. Not all enzymes are known and any relationships to cellulose properties remain unexplored. This study extends our successful mutational analysis of cellulose synthesis in Arabidopsis and initiates the molecular analysis of organisms making cellulose with distinctive properties. It will significantly advance knowledge of cellulose biosynthesis and identify novel genes for fibre improvement.Read moreRead less