New Techniques for Structural Biology and Directed Molecular Evolution. This PhD program will equip an Australian graduate with advanced training in techniques in molecular genetics and protein chemistry that are currently in high demand by the biotechnology industry, and also provide him/her with direct experience of an industrial R&D laboratory environment. Moreover, it will establish a basis for further collaboration between a leading University-based research laboratory and an established R& ....New Techniques for Structural Biology and Directed Molecular Evolution. This PhD program will equip an Australian graduate with advanced training in techniques in molecular genetics and protein chemistry that are currently in high demand by the biotechnology industry, and also provide him/her with direct experience of an industrial R&D laboratory environment. Moreover, it will establish a basis for further collaboration between a leading University-based research laboratory and an established R&D company that will lead to development of new techniques for use in biotechnology in Australia and overseas.Read moreRead less
A Fundamental Study on Redox Behaviour of Oxygen Carriers in Chemical Looping Combustion. Our goal here is to acquire fundamental knowledge about the redox behaviour of metal oxide oxygen carriers which, arguably, underpins the feasibility of the Chemical Looping Combustion (CLC) concept. Although the proposed work is fundamental and will contribute to the advancement of knowledge, the results will have immediate practical applications in power generation industry at both national and internatio ....A Fundamental Study on Redox Behaviour of Oxygen Carriers in Chemical Looping Combustion. Our goal here is to acquire fundamental knowledge about the redox behaviour of metal oxide oxygen carriers which, arguably, underpins the feasibility of the Chemical Looping Combustion (CLC) concept. Although the proposed work is fundamental and will contribute to the advancement of knowledge, the results will have immediate practical applications in power generation industry at both national and international levels. This should significantly contribute to the Australian Government's efforts in producing world class solutions for abatement of greenhouse emissions (Research Priority 1: An Environmentally Sustainable Australia, Priority Goal 1.4 - Reducing and capturing emissions in transport and energy generation).Read moreRead less
Development of nano-structured thermoelectric materials for power generation from heat. To make thermoelectric technology attractive for practical power generation purposes, new high efficiency materials have to be developed. Our fabricated nanostructured thermoelectric materials will have improved performance due to the peculiarities in electrical and thermal transport. The novel thermoelectric materials and constructed prototype devices with high thermoelectric performance will be practically ....Development of nano-structured thermoelectric materials for power generation from heat. To make thermoelectric technology attractive for practical power generation purposes, new high efficiency materials have to be developed. Our fabricated nanostructured thermoelectric materials will have improved performance due to the peculiarities in electrical and thermal transport. The novel thermoelectric materials and constructed prototype devices with high thermoelectric performance will be practically used for various power generation purposes. This offers a long-term solution to the global warming threat through decreasing amounts of waste heat presently generated. It will also strengthen Australia's position in world-wide research on thermoelectricity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454172
Funder
Australian Research Council
Funding Amount
$314,127.00
Summary
Facility for Analysis of Thermal Decomposition of Solid Materials at High Pressures. This submission aims to establish an integrated facility for studying the kinetics of solid and gas-solid reactions at elevated temperatures and high pressures; a piece of infrastructure that is urgently needed in Australia. The facility will consist of a high-pressure thermal gravimetric analyser (TGA) able to operate at up to 5 MPa, which will be coupled to a mass spectrometer (MS) for identification and quan ....Facility for Analysis of Thermal Decomposition of Solid Materials at High Pressures. This submission aims to establish an integrated facility for studying the kinetics of solid and gas-solid reactions at elevated temperatures and high pressures; a piece of infrastructure that is urgently needed in Australia. The facility will consist of a high-pressure thermal gravimetric analyser (TGA) able to operate at up to 5 MPa, which will be coupled to a mass spectrometer (MS) for identification and quantification of gaseous reaction products. The facility constitutes unique and significant national research infrastructure for the simultaneous acquisition of mass loss kinetic measurements together with characterisation and quantification of emission rates of gaseous fragments generated in the reaction. As a major outcome, the facility will provide a means for consistent investigation of kinetics of elemental reactions occurring in solids, or on solid surfaces during pyrolysis and gasification processes at high pressure.Read moreRead less
Pancreatic Differentiation of Cord Blood Stem Cells using Smart Surfaces. Cord blood cells obtained at the time of delivery of a baby are a valuable resource that have the potential to develop into many cell types. This Project entails attaching stem cells derived from cord blood to appropriate 3 dimensional smart surfaces, and examining the ability of such cells to develop into insulin-producing cells. An understanding of how to coax stem cells, seeded on to smart surfaces, to develop into ma ....Pancreatic Differentiation of Cord Blood Stem Cells using Smart Surfaces. Cord blood cells obtained at the time of delivery of a baby are a valuable resource that have the potential to develop into many cell types. This Project entails attaching stem cells derived from cord blood to appropriate 3 dimensional smart surfaces, and examining the ability of such cells to develop into insulin-producing cells. An understanding of how to coax stem cells, seeded on to smart surfaces, to develop into mature cells with different functions will enhance our ability to understand how cells develop. As well, it enhance the potential usefulness of cord blood for research purposes. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100001
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
An advanced thermogravimetric analysis system for world-leading research in clean energy, catalysis, material science and nanotechnology. Many chemical reactions occurring in solid materials during heating significantly affect the materials' stability, and subsequently affects the processes of production of clean energy, material synthesis, catalyst preparation, and nanotechnology. No equipment currently exists in Australia that will mitigate the wide range of conditions in such reactions in ma ....An advanced thermogravimetric analysis system for world-leading research in clean energy, catalysis, material science and nanotechnology. Many chemical reactions occurring in solid materials during heating significantly affect the materials' stability, and subsequently affects the processes of production of clean energy, material synthesis, catalyst preparation, and nanotechnology. No equipment currently exists in Australia that will mitigate the wide range of conditions in such reactions in materials processing. This situation impedes research progress in Australia, disadvantages Australian research students, and ultimately makes our research less competitive internationally. The establishment of the proposed apparatus will increase the competitiveness of Australian science and engineering, and contribute to the development of new Australian technologies that are important to the Australian economy and to environmental sustainability.Read moreRead less
Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs. The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types o ....Heparan sulfate complexes with VEGF for control of angiogenesis in tissue engineered constructs. The national/community benefits that will arise from this work include, the generation of knowledge related to the growth of blood vessels in the presence of a synthetic polymer that has been made to look like the natural polymers present in the body. This will lead to an understanding of the underlying mechanisms involved that may have down stream effects relevant to the replacement of many types of tissues being generated for clinical applications, including possible applications in the treatment of heart disease, the largest killer of people in the Western world. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100125
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and inter ....Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and international research collaborations, develop cutting-edge technology and unique local skills, and contribute to Australia maintaining a leading position in redox-related research in biology and medicine. In doing so, the facility will increase the likelihood of gaining future, value-adding funding.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237427
Funder
Australian Research Council
Funding Amount
$269,000.00
Summary
Equipment for Fluorescence-Based Cellular Analysis. The requested equipment is needed by a large grouping of highly productive researchers to carry out work across a very broad range of fields that is otherwise difficult or impossible to perform. The new equipment will facilitate obtaining many exciting and important outcomes, including identification of: (i) mechanisms controlling cell death, (ii) natural biological products that may have commercial applications (eg anti-fouling agents), (iii) ....Equipment for Fluorescence-Based Cellular Analysis. The requested equipment is needed by a large grouping of highly productive researchers to carry out work across a very broad range of fields that is otherwise difficult or impossible to perform. The new equipment will facilitate obtaining many exciting and important outcomes, including identification of: (i) mechanisms controlling cell death, (ii) natural biological products that may have commercial applications (eg anti-fouling agents), (iii) "probiotic" bacteria and vaccines that may be used to protect animals from disease, and (iv) mechanisms by which changes in human lens proteins contribute to the development of cataract.Read moreRead less
Ageing wild vertebrates from their DNA: an investigation using Humpback Whales as an example. The aim of this project is to estimate the age of individually identified humpback whales and the age structure of humpback whale populations using non-lethal, innovative molecular techniques. Populations of humpback whales in the Southern Hemisphere are slowly recovering from intensive whaling during the 20th century. This project is significant because it will provide the first comparative information ....Ageing wild vertebrates from their DNA: an investigation using Humpback Whales as an example. The aim of this project is to estimate the age of individually identified humpback whales and the age structure of humpback whale populations using non-lethal, innovative molecular techniques. Populations of humpback whales in the Southern Hemisphere are slowly recovering from intensive whaling during the 20th century. This project is significant because it will provide the first comparative information on the age structure of these populations, resulting in improved estimation of recovery and population dynamics of long-lived vertebrates. The results of this project will revolutionise research on ageing in whales and dolphins, providing an important alternative to lethal scientific whaling.Read moreRead less