Genome wide screening for gene products that regulate the celluar dynamics of lipid droplets. Obesity is a pandemic that if not stopped, will lead to huge social and economic problems in Australia. In essence, the hallmark of human obesity is the accumulation of cellular lipid droplets. This research will benefit Australia by providing a fundamental understanding of how lipid droplets are formed. This will have immediate international impact at the scientific level and will also provide novel ta ....Genome wide screening for gene products that regulate the celluar dynamics of lipid droplets. Obesity is a pandemic that if not stopped, will lead to huge social and economic problems in Australia. In essence, the hallmark of human obesity is the accumulation of cellular lipid droplets. This research will benefit Australia by providing a fundamental understanding of how lipid droplets are formed. This will have immediate international impact at the scientific level and will also provide novel targets and strategies for treating obesity. The proposed study will also benefit Australian agriculture by providing strategies to improve oil production from plant seeds. Read moreRead less
The cellular dynamics of lipid droplets: implications for obesity and biodiesel production. Obesity is a pandemic that if not stopped, will lead to huge social and economic problems in Australia. In essence, the hallmark of human obesity is the accumulation of cellular lipid droplets. This research will benefit Australia by providing a fundamental understanding of how lipid droplets are formed. This will have immediate international impact at the scientific level and will also identify novel com ....The cellular dynamics of lipid droplets: implications for obesity and biodiesel production. Obesity is a pandemic that if not stopped, will lead to huge social and economic problems in Australia. In essence, the hallmark of human obesity is the accumulation of cellular lipid droplets. This research will benefit Australia by providing a fundamental understanding of how lipid droplets are formed. This will have immediate international impact at the scientific level and will also identify novel compounds and strategies for treating obesity. The proposed study will also benefit Australian agriculture and energy industry by providing strategies to improve the production of plant oil and biodiesel. Read moreRead less
Protein Complexes and Supercomplexes of Plant Organelles. Ample parts of plant primary metabolism occur in subcellular structures called mitochondria, plastids and peroxisomes. They are vital for plant growth and development and are central to the early success of germinating and growing seedlings. This project intends to analyze the protein complexes and supercomplexes within these organelles using state of the art instrumentation and technologies. Findings from this research have the potential ....Protein Complexes and Supercomplexes of Plant Organelles. Ample parts of plant primary metabolism occur in subcellular structures called mitochondria, plastids and peroxisomes. They are vital for plant growth and development and are central to the early success of germinating and growing seedlings. This project intends to analyze the protein complexes and supercomplexes within these organelles using state of the art instrumentation and technologies. Findings from this research have the potential to directly flow into the plant biotechnology industry and could assist the future development of Australian agriculture through genetic improvements. The expertise developed by this work will ensure that Australia is well placed to meet future needs and to generally improve agricultural technology. Read moreRead less
Adaptations of plant mitochondria during cold acclimation in Arabidopsis thaliana: towards an understanding of plant cold acclimation. Frost damage is a major cost to agricultural producers and some crop plant species needlessly adapt to cold, when they are grown in temperate regions or in glasshouses, which leads to decreased production. The principal outcome of this project will be to greatly extend our knowledge about plant mitochondrial responses to environmental cold stress and what role th ....Adaptations of plant mitochondria during cold acclimation in Arabidopsis thaliana: towards an understanding of plant cold acclimation. Frost damage is a major cost to agricultural producers and some crop plant species needlessly adapt to cold, when they are grown in temperate regions or in glasshouses, which leads to decreased production. The principal outcome of this project will be to greatly extend our knowledge about plant mitochondrial responses to environmental cold stress and what role they have in helping plants adapt to environmental change. An understanding of cold acclimation may allow the production of plants with altered cold acclimation phenotypes and greater frost tolerance.Read moreRead less