ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longi ....ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longitudinal family cohort study and children’s technology laboratories. The Centre will address tensions in a contested field to inform government and non-government policy, technology innovation, and develop programs and guidelines for children, families, educators and technology developers. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347607
Funder
Australian Research Council
Funding Amount
$306,000.00
Summary
FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged ex ....FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged expertise as well as priority within their respective institutions. In addition, it will facilitate wide-ranging collaborative arrangements to further develop and exploit this research area.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100211
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and developmen ....The Big Australian Speech Corpus: An audio-visual speech corpus of Australian English. Contemporary speech science and technology are driven by the availability of large speech corpora. While audio databases exist for languages spoken in America, Europe and Japan, there is currently no large auditory-visual database of spoken language, and certainly not one for Australian English. Here we will establish the Big Australian Speech Corpus, which will support a speech science research and development using Australian English and facilitate the development of Australian speech technology applications from automatic speech recognition and text-to-speech synthesis used in taxi and other ordering services, to hearing prostheses and talking head aids for learning-impaired children, and a range of security and forensic applications.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100019
Funder
Australian Research Council
Funding Amount
$4,583,816.00
Summary
ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective dig ....ARC Training Centre for Optimal Ageing. The ARC Training Centre for Optimal Ageing aims to address issues identified by older adults as essential for quality of life. With our industry partners, we aim to train the next generation of researchers to understand, detect and improve psychosocial factors that support mental activity, physical health and social connectedness, and embrace advances in artificial intelligence, digital-enriched environments and adaptive workplaces to deliver effective digital solutions. By developing new capacity and capability to drive the digital transformation of industries supporting our ageing population, our Centre seeks to deliver economic and social benefits that enable Australians to live enriched, healthy and independent lives as they age.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668241
Funder
Australian Research Council
Funding Amount
$824,610.00
Summary
A Facility for High-Throughput, Functional Gene Discovery Using Arrayed Retroviral Expression Cloning. The proposed facility will represent world-leading technology in functional genomics and provide Australian scientists with unique opportunities to identify genes involved in a broad range of biological processes. This will contribute to fundamental knowledge in mammalian biology, and equally importantly, is likely to identify genes involved in important health problems such as cancer, inflamma ....A Facility for High-Throughput, Functional Gene Discovery Using Arrayed Retroviral Expression Cloning. The proposed facility will represent world-leading technology in functional genomics and provide Australian scientists with unique opportunities to identify genes involved in a broad range of biological processes. This will contribute to fundamental knowledge in mammalian biology, and equally importantly, is likely to identify genes involved in important health problems such as cancer, inflammatory disease, brain damage and diabetes. Such genes may in turn constitute targets against which new therapies may be developed. This endeavour will contribute to national research priorities in both the health and scientific/technological development arenas.Read moreRead less
ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory ne ....ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory networks and to address how environmental factors impinge on these regulatory networks. The formation of this National Research Network is unique, timely and strategic. It will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
Unravelling the principles of bilateral brain wiring. This project seeks to investigate the molecular principles of brain wiring in mammals and how small changes can generate complex outcomes. Neurons in the mammalian brain must be precisely wired together for the brain to function correctly. The project aims to identify the molecular and cellular rules governing commissural wiring in the mammalian cortex to determine how the largest fibre tract in the human brain, the corpus callosum, evolved. ....Unravelling the principles of bilateral brain wiring. This project seeks to investigate the molecular principles of brain wiring in mammals and how small changes can generate complex outcomes. Neurons in the mammalian brain must be precisely wired together for the brain to function correctly. The project aims to identify the molecular and cellular rules governing commissural wiring in the mammalian cortex to determine how the largest fibre tract in the human brain, the corpus callosum, evolved. This may have involved modifications in mechanisms affecting axon guidance that differ between placentals and marsupials. The project investigates the regulatory gene networks determining commissural neuron fate, the regulation of axon guidance components, and the influence of surrounding brain tissue on the development of commissural connections.Read moreRead less
Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations t ....Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations that optimise plant yield and fitness will be defined and explored in other, more complex, cereals such as wheat. Expected outcomes will be fundamental breakthroughs in understanding how plants respond to, and buffer, the effects of heat to lead to translational breeding strategies that bolster grain yield.Read moreRead less
ARC Centre of Excellence in Plant Cell Wall Biology. The ARC Centre for Plant Cell Wall Biology will define the regulatory mechanisms that control molecular, enzymic and cellular processes involved in the synthesis, deposition, re-modelling and depolymerisation of cell wall polysaccharides of cereals and grasses. Plant cell walls represent the world's largest renewable carbon resource, but the regulatory mechanisms responsible for their synthesis and assembly are not understood. Key distinguishi ....ARC Centre of Excellence in Plant Cell Wall Biology. The ARC Centre for Plant Cell Wall Biology will define the regulatory mechanisms that control molecular, enzymic and cellular processes involved in the synthesis, deposition, re-modelling and depolymerisation of cell wall polysaccharides of cereals and grasses. Plant cell walls represent the world's largest renewable carbon resource, but the regulatory mechanisms responsible for their synthesis and assembly are not understood. Key distinguishing features of the Centre will be the international, integrative, and multidisciplinary approach towards addressing major questions in plant biology, its strategy to leverage ARC funding, and its linkages with potential national and international end-users of the fundamental scientific discoveries.Read moreRead less
Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative ....Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative that could be incorporated into DTA programs if their ecological relevance can be demonstrated. This project will develop and validate a new and internationally significant suite of in vitro bioassays for incorporation into DTA programs, leading to more ethical, cost effective and improved environmental protection.Read moreRead less