Location-Based Personalisation in Mobile Commerce (M-Commerce). M-commerce, though playing an important role in future competitiveness of Australia, suffers a low user demand. While location-based services have taken off in Europe, they are still at their infancy in Australia. In terms of IT access, Australia is ranked lower than many Asian countries. Our work gains an understanding of users' concerns and expectations of location-based services, which leads to better application designs and thus ....Location-Based Personalisation in Mobile Commerce (M-Commerce). M-commerce, though playing an important role in future competitiveness of Australia, suffers a low user demand. While location-based services have taken off in Europe, they are still at their infancy in Australia. In terms of IT access, Australia is ranked lower than many Asian countries. Our work gains an understanding of users' concerns and expectations of location-based services, which leads to better application designs and thus a wider adoption. An examination of users' attitude towards personalised content and concerns about data privacy provides insights to Australian legislation in relation to telemarketing and data-driven marketing. National benefits will stem from a balance between telemarketing efficiency and users' benefits.Read moreRead less
Improving the specificity of affective computing via multimodal analysis. This project aims to develop multimodal affective sensing techniques that can sense very subtle expressions in human moods and emotions. Much research in affective computing has investigated ways to improve the sensitivity of affect sensing approaches, resulting in more accurate estimates of affective states such as emotions or mood. What remains unsolved so far is the issue of specificity. This project will address this i ....Improving the specificity of affective computing via multimodal analysis. This project aims to develop multimodal affective sensing techniques that can sense very subtle expressions in human moods and emotions. Much research in affective computing has investigated ways to improve the sensitivity of affect sensing approaches, resulting in more accurate estimates of affective states such as emotions or mood. What remains unsolved so far is the issue of specificity. This project will address this issue through novel analyses of very subtle cues in facial and vocal expressions of affect embedded in a multimodal deep learning framework. Current approaches can successfully assist in binary classification tasks. This project will tackle the much more difficult problem of developing advanced affective sensing technology to simultaneously handle homogeneous and heterogeneous affect classes as well as continuous range estimates of affect intensity.Read moreRead less
Finding and exploiting interesting paths in multidimensional information spaces. This project will invent a new approach for searching within a large complex information space, finding interesting paths between points within the space, visualising the results, and supporting rich, human-centric user interaction with queries and results. This project will embody these techniques in a novel, internet-scale framework to support rapid development of large path search and visualisation applications. ....Finding and exploiting interesting paths in multidimensional information spaces. This project will invent a new approach for searching within a large complex information space, finding interesting paths between points within the space, visualising the results, and supporting rich, human-centric user interaction with queries and results. This project will embody these techniques in a novel, internet-scale framework to support rapid development of large path search and visualisation applications. Evaluation will be via development of several exemplar applications. The techniques and framework will be applicable to a broad range of economically important problems in areas as diverse as health, travel, scientific publication search, product marketing and software engineering.Read moreRead less
Adaptive modelling of human responses in complex interaction. This project aims to combine strengths of human cognition and evolutionary computing to efficiently solve problems which neither can do alone. The project will develop techniques combining advanced non-intrusive sensor measures of behaviour and emotional reaction in interaction tasks to enable high level computer support for human goal seeking, in complex data and design environments. This project will allow non-expert users to use to ....Adaptive modelling of human responses in complex interaction. This project aims to combine strengths of human cognition and evolutionary computing to efficiently solve problems which neither can do alone. The project will develop techniques combining advanced non-intrusive sensor measures of behaviour and emotional reaction in interaction tasks to enable high level computer support for human goal seeking, in complex data and design environments. This project will allow non-expert users to use tools normally requiring extensive training in settings where the user can 'see' when they get something they like but do not know how to instruct a computer system to show or do it. Applications of the project will include visualisation for bespoke manufacturing or for high dimensional data, generating abstract art, or improving teleconferencing systems.Read moreRead less
Parametric VR: An Interactive Virtual Reality System for Parametric Design. This project aims to create a new and intuitive set of user interactions for Virtual Reality (VR) to support parametric designers in architecture and design. Parametric tools are an emerging design technology dominating contemporary practices, yet their interfaces are on traditional desktop computers while VR is only employed to visualise the geometric models produced by the end design. This project will generate Paramet ....Parametric VR: An Interactive Virtual Reality System for Parametric Design. This project aims to create a new and intuitive set of user interactions for Virtual Reality (VR) to support parametric designers in architecture and design. Parametric tools are an emerging design technology dominating contemporary practices, yet their interfaces are on traditional desktop computers while VR is only employed to visualise the geometric models produced by the end design. This project will generate Parametric VR, a system of VR tools to support parametric design. Key outcomes include software tools and demonstrators to support parametric algorithms and processes in VR. This will have significant benefits for design industries, allowing designers to directly edit parametric design entirely in VR across the project lifecycle.Read moreRead less
Biogenesis of red blood cell membrane modifications by the malaria parasite Plasmodium falciparum. Malaria is not only a major global health problem, but also affects countries neighbouring Australia like Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (aid and military personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identi ....Biogenesis of red blood cell membrane modifications by the malaria parasite Plasmodium falciparum. Malaria is not only a major global health problem, but also affects countries neighbouring Australia like Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (aid and military personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identify new intervention targets for Plasmodium falciparum infection. Developing novel targets is mandated by humanity, but also to safeguard Australia's region against the social and economic implications of this disease. An Australian developed intervention would increase the global visibility of its science, leading to increased investments.Read moreRead less
Taming the intruders: the domestication of Tigger transposable elements in mammals. It has become apparent that most of the DNA that makes us what we are is actually comprised of the remnants of invading parasitic DNA acquired over time. A continual battle exists between host which tries to silence or remove this DNA, and the parasite that tries to multiply and spread. We are currently investigating an intriguing aspect of this process that involves host genomes 'domesticating' parasitic DNA to ....Taming the intruders: the domestication of Tigger transposable elements in mammals. It has become apparent that most of the DNA that makes us what we are is actually comprised of the remnants of invading parasitic DNA acquired over time. A continual battle exists between host which tries to silence or remove this DNA, and the parasite that tries to multiply and spread. We are currently investigating an intriguing aspect of this process that involves host genomes 'domesticating' parasitic DNA to provide novel functions, thereby facilitating the evolution of specific characteristics within species.Read moreRead less
Functional Genomic Analysis of Exported DNAJ Molecules in the Malaria Parasite Plasmodium falciparum. Malaria is not only a global health problem, but also affects countries surrounding Australia like PNG and Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (eg. aid and security personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology t ....Functional Genomic Analysis of Exported DNAJ Molecules in the Malaria Parasite Plasmodium falciparum. Malaria is not only a global health problem, but also affects countries surrounding Australia like PNG and Indonesia, reducing the region's stability and prosperity. Environmental changes and increased mobility of people (eg. aid and security personnel) make Australia itself more prone to malaria. The project will translate recent genomic data into functional insights using frontier technology to identify new intervention targets for P. falciparum infection. Developing novel targets is mandated by humanity, and also to safeguard Australia's region against the social and economical implication of this disease. An Australian developed intervention would increase the global visibility of its science, leading to increased investments.Read moreRead less
Development of Model Systems to Investigate Blood Hydrodynamic Parameters Affecting Blood Cell Function: An Interdisciplinary Approach. National benefit will come through this research contributing to a better understanding of blood flow biology and pathology, both of which are of particular relevance to the aging Australian population. This benefit is well aligned with the 2008 National research priority 2: Promoting and Maintaining Good Health; Priority Goal 3. Preventative Health. The synthes ....Development of Model Systems to Investigate Blood Hydrodynamic Parameters Affecting Blood Cell Function: An Interdisciplinary Approach. National benefit will come through this research contributing to a better understanding of blood flow biology and pathology, both of which are of particular relevance to the aging Australian population. This benefit is well aligned with the 2008 National research priority 2: Promoting and Maintaining Good Health; Priority Goal 3. Preventative Health. The synthesis of both extensive expertise in platelet/cardiovascular research and bioengineering/rheology should provide a substantial platform from which fundamental new discoveries in this niche area can be made. The development of novel platelet analysis tools arising from this work may also ultimately lead to new intellectual property and attract industry based funding.Read moreRead less
Examination of the Calcium Signalling Dynamics Linked to Integrin Adhesion Utilising a Novel Micro-imaging System. This study aims at increasing our understanding of the fundamental cell processes that allow cells to adhere to surfaces. The proposed study will lead to a greater understanding of the calcium signalling mechanisms that are fundamental to diverse biological phenomena such as, tissue regeneration and repair, blood clotting, cancer metastasis, and neuronal cell function. From a preven ....Examination of the Calcium Signalling Dynamics Linked to Integrin Adhesion Utilising a Novel Micro-imaging System. This study aims at increasing our understanding of the fundamental cell processes that allow cells to adhere to surfaces. The proposed study will lead to a greater understanding of the calcium signalling mechanisms that are fundamental to diverse biological phenomena such as, tissue regeneration and repair, blood clotting, cancer metastasis, and neuronal cell function. From a preventative health perspective, the investigation of platelet calcium signalling will greatly accelerate the development of new pharmaceuticals to tackle acute and chronic cardiovascular diseases, such as stroke, heart attack and artherosclerosis. Read moreRead less