Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100121
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Three-dimensional super-resolution nanophotonic fabrication facility. This stimulated emission depletion microscopy nanophotonic fabrication facility will be the first nanophotonic fabrication facility that is able to achieve optical resolution far beyond the diffraction limit, which will facilitate breakthroughs in cutting-edge nanotechnology research areas.
Investigating The Cellular Response To Iron-Depletion: The Trilogy Of ASK1, Thioredoxin And Ribonucleotide Reductase
Funder
National Health and Medical Research Council
Funding Amount
$552,572.00
Summary
Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for t ....Iron is crucial for many essential biological processes. Recently, we demonstrated that iron-depletion can affects important signalling pathways (e.g., JNK and p38) that play important roles in growth arrest and apoptosis. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. The research is crucial for understanding: (1) the effects of iron deficiency and (2) for understanding the effects of iron chelators that are used for treating various diseases.Read moreRead less
Is transport of miRNAs essential for plant development? This project will provide knowledge of how a new class of biologically active molecule (micro RNA) regulates expression of genes at sites in the plant that are critical for growth and development. MicroRNAs are believed to influence the size and shape of plants, how rapidly they grow and how well they produce and fill seeds. These molecules are part of a group of bioactive signals that move throughout the plant, functioning like hormones bu ....Is transport of miRNAs essential for plant development? This project will provide knowledge of how a new class of biologically active molecule (micro RNA) regulates expression of genes at sites in the plant that are critical for growth and development. MicroRNAs are believed to influence the size and shape of plants, how rapidly they grow and how well they produce and fill seeds. These molecules are part of a group of bioactive signals that move throughout the plant, functioning like hormones but directly influencing how well critical genes work. Their exploitation holds great promise for manipulating plant performance and enhancing crop yields. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100003
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin ....3D Nanofabrication and Nanocharacterisation facility. This project aims to establish a revolutionary nanoscale fabrication and characterisation facility in Australia. The facility is an angle-based nanoscale etching system with integrated chemical analysis capabilities and will be the first instrument of its kind in Australia. The facility will enable unprecedented fabrication and characterisation of 3D nanostructures and new device geometries from semiconductors, oxides and metals that underpin modern nanoelectronics for innovative energy, nano-optical and quantum device applications. This unique equipment will facilitate breakthrough discoveries in nanomaterials, and foster collaborations amongst Australian researchers to accelerate industry in advanced nanodevice technologies.Read moreRead less
Genome Approaches to Investigate Metabolic Coordination in Plant Cells. Metabolism of C and N in legume nodules requires interaction between the symbiotic bacteria and plant organelles, particularly metabolism in plastids and mitochondria. Fixed N is assimilated through the de novo synthesis of purines in both plastids and mitochondria. However, each of the nine pathway enzymes is encoded by a single gene, indicating each protein is targeted to both organelles. Purine metabolism will provide ....Genome Approaches to Investigate Metabolic Coordination in Plant Cells. Metabolism of C and N in legume nodules requires interaction between the symbiotic bacteria and plant organelles, particularly metabolism in plastids and mitochondria. Fixed N is assimilated through the de novo synthesis of purines in both plastids and mitochondria. However, each of the nine pathway enzymes is encoded by a single gene, indicating each protein is targeted to both organelles. Purine metabolism will provide a model to assess the more general occurrence of dual-targeted proteins in plants. The aim is to identify and eventually exploit the signalling mechanism(s) that mediate communication between plastids and mitochondria.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100125
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and inter ....Oxidative stress bioanalytical facility. The primary national benefit of this application is that it will provide a currently unavailable, state-of-the-art facility for Australian scientists to define precisely how changes in cellular redox state contribute to biological processes relevant to health and diseases. The facility will uniquely complement, and in many cases integrate with existing facilities in this area of research in Australia. It will act as a platform for major national and international research collaborations, develop cutting-edge technology and unique local skills, and contribute to Australia maintaining a leading position in redox-related research in biology and medicine. In doing so, the facility will increase the likelihood of gaining future, value-adding funding.Read moreRead less
Institutions for Food Security: Global Lessons from Rural India. Between 2006 and 2008, global progress in combating world hunger stalled. World food prices increased by 71.4% and an additional 115 million people joined the ranks of the undernourished. This is a human tragedy which has fuelled political and economic turmoil across many countries. India has 28% of the world's hungry, and is an increasingly important economic and political partner to Australia. This research will involve a team of ....Institutions for Food Security: Global Lessons from Rural India. Between 2006 and 2008, global progress in combating world hunger stalled. World food prices increased by 71.4% and an additional 115 million people joined the ranks of the undernourished. This is a human tragedy which has fuelled political and economic turmoil across many countries. India has 28% of the world's hungry, and is an increasingly important economic and political partner to Australia. This research will involve a team of Australian researchers working with Indian counterparts to develop a framework that explains what causes risk and resilience to food insecurity, and offers practical insights for policy-makers. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100006
Funder
Australian Research Council
Funding Amount
$1,060,000.00
Summary
Ultra-high resolution focussed ion beam facility for Western Australia. Ultra-high resolution focussed ion beam facility: An ultra-high resolution dual beam facility (incorporating ion and electron beams) will provide 3D imaging, site-specific analysis and nano-machining to a wide range of internationally recognised Australian researchers across a broad spectrum of disciplines in the geosciences, engineering, biological and physical sciences. Providing critically needed access to this world-clas ....Ultra-high resolution focussed ion beam facility for Western Australia. Ultra-high resolution focussed ion beam facility: An ultra-high resolution dual beam facility (incorporating ion and electron beams) will provide 3D imaging, site-specific analysis and nano-machining to a wide range of internationally recognised Australian researchers across a broad spectrum of disciplines in the geosciences, engineering, biological and physical sciences. Providing critically needed access to this world-class infrastructure is expected to advance international competitiveness, leading to high-impact outcomes in smart materials, nanotechnology, bioscience, and geoscience, including support for the Australian resources sector.Read moreRead less
Ageing in a developing country and its effects on intra-household resource allocation. Indonesia, our largest neighbour and our third largest recipient of AID, is among the fastest-growing elderly populations in Southeast Asia. Ongoing cultural and economic change means that the traditional reliance of elderly on family support is breaking down leaving the country's social fabric vulnerable. Understanding the linkages between ageing, ill-health and the labour market responses at the household le ....Ageing in a developing country and its effects on intra-household resource allocation. Indonesia, our largest neighbour and our third largest recipient of AID, is among the fastest-growing elderly populations in Southeast Asia. Ongoing cultural and economic change means that the traditional reliance of elderly on family support is breaking down leaving the country's social fabric vulnerable. Understanding the linkages between ageing, ill-health and the labour market responses at the household level is the path to effectively intervene in the link between age and poverty and to successfully design policy that facilitates improvements in women's social status.Read moreRead less