The Geopolitics of Automation. Automation threatens economic disruption. The Project aims to understand how competition between China and the US to develop automated technologies shapes the future of work. Focusing on warehouses linked to Alibaba and Amazon in Australia, Germany and Malaysia, the Project asks how automation changes labour conditions and modifies geopolitical tensions. Digital simulations of automated technologies in warehouses key to the China-US rivalry will seek to augment kno ....The Geopolitics of Automation. Automation threatens economic disruption. The Project aims to understand how competition between China and the US to develop automated technologies shapes the future of work. Focusing on warehouses linked to Alibaba and Amazon in Australia, Germany and Malaysia, the Project asks how automation changes labour conditions and modifies geopolitical tensions. Digital simulations of automated technologies in warehouses key to the China-US rivalry will seek to augment knowledge about the governance of labour and territory. Intended outcomes include insights into how automation is a geopolitical and economic concern for policy makers. Benefits should offer strategies for organisations negotiating automation’s effects on workforces.Read moreRead less
Decoding the spatiotemporal control of DNA replication and repair. DNA replication is the fundamental mechanism of genetic inheritance and essential for all cellular life. This project aims to inform our understanding of how human cells coordinate the DNA replication machinery in time and space to accurately copy the human genome. By applying multiple innovative approaches and employing an interdisciplinary research team, this project is anticipated to generate new knowledge that explains how th ....Decoding the spatiotemporal control of DNA replication and repair. DNA replication is the fundamental mechanism of genetic inheritance and essential for all cellular life. This project aims to inform our understanding of how human cells coordinate the DNA replication machinery in time and space to accurately copy the human genome. By applying multiple innovative approaches and employing an interdisciplinary research team, this project is anticipated to generate new knowledge that explains how the human genome is replicated. This knowledge is expected to generate research publications of high quality and provide economic benefits, such as unlocking new potentially patentable DNA technologies. Read moreRead less
Regulation of 3D Cell Migration by Microtubule-Dependent Processes. The overarching aim of this research is to elucidate the molecular mechanisms that cells use to move in 3D environments: a basic biological function essential to development and homeostasis. During these processes, cells interact with their surroundings where they translate biophysical forces into biochemical signals to adapt their shape to move. This requires distinct signalling, controlled in space and time, to regulate the cr ....Regulation of 3D Cell Migration by Microtubule-Dependent Processes. The overarching aim of this research is to elucidate the molecular mechanisms that cells use to move in 3D environments: a basic biological function essential to development and homeostasis. During these processes, cells interact with their surroundings where they translate biophysical forces into biochemical signals to adapt their shape to move. This requires distinct signalling, controlled in space and time, to regulate the crosstalk between organelles and the cytoskeleton. To date, the role of microtubules remains elusive. Using interdisciplinary approaches combining advanced imaging technology with novel cell biology methods, the project aims to uncover fundamental knowledge about how cells interact with their environment.Read moreRead less
Understanding platinum dissolution in biomedical stimulating electrodes. Platinum is the main material used in electrodes for neurostimulators like the cochlear implant. Platinum electrodes can experience dissolution during implantation, which can impact on their function. The mechanisms governing this dissolution process are complex and still not fully understood. This research aims to understand the chemical, electrical and biological factors that impact on platinum dissolution in electrodes. ....Understanding platinum dissolution in biomedical stimulating electrodes. Platinum is the main material used in electrodes for neurostimulators like the cochlear implant. Platinum electrodes can experience dissolution during implantation, which can impact on their function. The mechanisms governing this dissolution process are complex and still not fully understood. This research aims to understand the chemical, electrical and biological factors that impact on platinum dissolution in electrodes. It will also develop new 3D models to simulate conditions in the human body for more rapid testing of electrodes. The new knowledge generated will improve the accuracy of predictions of platinum dissolution, develop new approaches for minimising dissolution, and contribute to reducing need for animal experimentation.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100486
Funder
Australian Research Council
Funding Amount
$363,182.00
Summary
Drone witnessing: technologies of perception in war and culture. This project aims to investigate how drones and other technologies of perception are changing how we bear witness and determine the meaning, importance and truth of events. The project will generate new knowledge about the impact of drone warfare and drone technologies on forms and processes of witnessing by analysing both primary and creative texts and by conducting field research into new practices of testimony. Anticipated outco ....Drone witnessing: technologies of perception in war and culture. This project aims to investigate how drones and other technologies of perception are changing how we bear witness and determine the meaning, importance and truth of events. The project will generate new knowledge about the impact of drone warfare and drone technologies on forms and processes of witnessing by analysing both primary and creative texts and by conducting field research into new practices of testimony. Anticipated outcomes include a critical and conceptual framework for witnessing, new terms to inform public debates about the cultural impact of increased reliance on drones in war and culture, and new channels for knowledge exchange between drone and autonomous system designers, humanities scholars and creative practitioners.Read moreRead less
Mapping networks governing cell state plasticity: how, where and when? Single cell organisms are the basic unit of life, yet, if they had not developed the ability to change cell states we would not exist today. Changing cell states lies at the core of almost every developmental and disease process in multicellular organisms. Building upon our fundamental discovery that stem cells and non-stem cells readily interconvert, we will now incorporate innovative cell systems and the development of our ....Mapping networks governing cell state plasticity: how, where and when? Single cell organisms are the basic unit of life, yet, if they had not developed the ability to change cell states we would not exist today. Changing cell states lies at the core of almost every developmental and disease process in multicellular organisms. Building upon our fundamental discovery that stem cells and non-stem cells readily interconvert, we will now incorporate innovative cell systems and the development of our new multi-layered systems biology strategy to elucidate the first comprehensive understanding of the cell biology that underlies cell state changes. These studies are a major step toward understanding the fundamentals of life. Read moreRead less
Digital media, location awareness, and the politics of geodata. This project aims to examine the increasingly pervasive role of location metadata, or geodata, in Australian smartphone practices and cultures and the implications this has for users, industry, and public administration. The project will deliver online and open resources to enhance public understanding of geodata and geoprivacy, as well as industry and policy recommendations that address the crucial issue of ‘location awareness’ in ....Digital media, location awareness, and the politics of geodata. This project aims to examine the increasingly pervasive role of location metadata, or geodata, in Australian smartphone practices and cultures and the implications this has for users, industry, and public administration. The project will deliver online and open resources to enhance public understanding of geodata and geoprivacy, as well as industry and policy recommendations that address the crucial issue of ‘location awareness’ in everyday digital media use. The project will generate new insights into the critical role of geodata in everyday digital media use and will contribute to broader public discussion about data privacy, surveillance and cybersecurity. Its findings will also provide industry benefits, enhancing developers’ understanding of how everyday users apprehend and negotiate the privacy implications of location services.Read moreRead less
Communicating to promote engagement in using electronic medical records. This reflexive ethnographic and co-design project aims to examine how patient and family participation occurs with health professionals in using the electronic medical record within hospitals, especially for patients with complex needs. Its significance involves working with patients and families to consider how they could take part in decision making activities across transitions of care and influence health care activitie ....Communicating to promote engagement in using electronic medical records. This reflexive ethnographic and co-design project aims to examine how patient and family participation occurs with health professionals in using the electronic medical record within hospitals, especially for patients with complex needs. Its significance involves working with patients and families to consider how they could take part in decision making activities across transitions of care and influence health care activities. Outcomes are new knowledge and practices about how communication occurs with the electronic medical record and strategies adopted for effective engagement. Benefits are increased understanding of how and under what circumstances, engagement can take place in using the electronic medical record.Read moreRead less
Deciphering new regulators of lipid metabolism: a focus on lipid droplets . Lipid droplets store lipids in cells and the mitochondria break down this lipid to generate energy. Both organelles are critical for energy metabolism and cell survival. This project aims to determine the proteins that regulate the interaction between mitochondria and lipid droplets, and how these proteins regulate metabolism. It is anticipated that this project will identify the essential components of lipid droplet-mit ....Deciphering new regulators of lipid metabolism: a focus on lipid droplets . Lipid droplets store lipids in cells and the mitochondria break down this lipid to generate energy. Both organelles are critical for energy metabolism and cell survival. This project aims to determine the proteins that regulate the interaction between mitochondria and lipid droplets, and how these proteins regulate metabolism. It is anticipated that this project will identify the essential components of lipid droplet-mitochondria interactions and their impact on regulating cellular lipid metabolism. The intended outcome of this project is to provide fundamental new knowledge in understanding how organelles interact and how lipid metabolism is regulated. This knowledge has applications for the primary industries and biotechnology sector.Read moreRead less
Imaging the foundation of the nervous system. This Project aims to understand the formation of the neural tube; a fundamental tissue structure that generates the brain and the spinal cord. Using interdisciplinary approaches and exploiting recent advances in transgenic and imaging technologies, the Project expects to reveal the complex interplay of molecular, cellular and mechanical processes that direct neural tissue formation and cell fate specification. Outcomes from the Project include knowle ....Imaging the foundation of the nervous system. This Project aims to understand the formation of the neural tube; a fundamental tissue structure that generates the brain and the spinal cord. Using interdisciplinary approaches and exploiting recent advances in transgenic and imaging technologies, the Project expects to reveal the complex interplay of molecular, cellular and mechanical processes that direct neural tissue formation and cell fate specification. Outcomes from the Project include knowledge of previously intractable developmental processes, training of future scientists and development of international collaborations. This should provide enhanced imaging capacity, a higher quality scientific workforce and position Australia at the forefront of developmental biology.
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