Ubiquitin And SUMO DNA Damage Response Signalling At Deprotected Telomeres During The Cell Cycle
Funder
National Health and Medical Research Council
Funding Amount
$302,627.00
Summary
Following genome damage cells stop the cell division process and initiate DNA repair. We discovered that at specific times during cell division his does not happen if the damage signals originate from the chromosome ends (i.e. “telomeres”). We anticipate this is necessary to prevent genomic instability in healthy cells and may be driving genomic instability in cancer cells. Experiments described here will elucidate the molecular mechanisms and biological significance of our observation.
A nation of 'Good Sports'? Cultural citizenship and sport in contemporary Australia. Australia is widely regarded as both characterised and united by sport, but the established sport-nation nexus is undergoing significant change. This project addresses current uses and meanings of sport, media and spectatorship in advancing knowledge and policy relating to sport's dynamic relationship to national identity and cultural citizenship.
Communicating with people who have limited English proficiency. This sociolinguistic project aims to investigate how fluent English speakers interact with people who have limited proficiency. In contemporary Australia such mundane interactions may determine employment, education or health outcomes. While research into language barriers has mostly focused on the experiences of migrants from non-English-speaking backgrounds, this project will investigate how English speakers deal with increasing l ....Communicating with people who have limited English proficiency. This sociolinguistic project aims to investigate how fluent English speakers interact with people who have limited proficiency. In contemporary Australia such mundane interactions may determine employment, education or health outcomes. While research into language barriers has mostly focused on the experiences of migrants from non-English-speaking backgrounds, this project will investigate how English speakers deal with increasing linguistic diversity. Expected outcomes include an understanding of the role of majority members in facilitating the integration of newcomers. This will provide significant socioeconomic benefits for institutions and individuals as they navigate everyday intercultural communication.Read moreRead less
Voice, indexicality and the mediation of diversity on Australian television. Multicultural Australia is a country of many voices, although concern has been expressed about the under-representation of those voices in the media. This project investigates how the voices of minority groups are represented on mainstream Australian television, when they do appear. It examines a substantial body of TV data, from four types of programming: news, sports, advertising and drama. It focuses on minority ethn ....Voice, indexicality and the mediation of diversity on Australian television. Multicultural Australia is a country of many voices, although concern has been expressed about the under-representation of those voices in the media. This project investigates how the voices of minority groups are represented on mainstream Australian television, when they do appear. It examines a substantial body of TV data, from four types of programming: news, sports, advertising and drama. It focuses on minority ethnic voices and on voices linked to different social classes. Close analysis of media processes will be supplemented by consulting professionals and TV viewers. The findings will provide a new perspective on the media’s role in promoting or curtailing cultural literacy and linguistic diversity.Read moreRead less
Reconceiving the queer public sphere: an interdisciplinary analysis of same-sex couple domesticity. Using literary, biographical and photographic sources, this project will produce a ground-breaking history of same-sex domestic environments across the twentieth century. Critically analysing queer home life, this project will transform current understandings of the relation between homosexuality, private life and the public sphere.
Governing Prostitution in the People's Republic of China. This project will generate knowledge for 'Understanding Our Region and the World', part of the National Research Priority-Safeguarding Australia. It will do so by producing the first detailed study of the governmental regulation of prostitution in present-day China. Its impact will be increased knowledge of different, local responses to the governance of prostitution businesses and practices. It will position Australian research at the in ....Governing Prostitution in the People's Republic of China. This project will generate knowledge for 'Understanding Our Region and the World', part of the National Research Priority-Safeguarding Australia. It will do so by producing the first detailed study of the governmental regulation of prostitution in present-day China. Its impact will be increased knowledge of different, local responses to the governance of prostitution businesses and practices. It will position Australian research at the international forefront of this field, thereby enabling Australian researchers to lead and contribute to international policy debate on prostitution, public health issues and related government regulation.Read moreRead less
International perspectives on the regulation of young people's user-generated content. This project will examine international regulatory strategies for explicit user-generated content and suggest ways in which academics, policy makers and globally networked content users can be brought into dialogue so as to generate better informed and more effective regulatory policies.
The Embodiment of Melancholy: A Feminist Analysis of Depression. This project is a multidisciplinary investigation of depression. Drawing on a wealth of biomedical data about depression, and integrating this with psychodynamic research and feminist theories of embodiment, the project will develop robust theoretical tools for understanding the impact of endemic depression on the body. How are depressive states internalised in the biochemistry, behavioural repertoires and imaginary schemata of o ....The Embodiment of Melancholy: A Feminist Analysis of Depression. This project is a multidisciplinary investigation of depression. Drawing on a wealth of biomedical data about depression, and integrating this with psychodynamic research and feminist theories of embodiment, the project will develop robust theoretical tools for understanding the impact of endemic depression on the body. How are depressive states internalised in the biochemistry, behavioural repertoires and imaginary schemata of our bodies? Focusing on pharmacology, the gut, gender, sexuality and infancy the project will (1) transform how feminists use biological data about the body and (2) expand the affective profile through which feminists have analysed depression.
Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100099
Funder
Australian Research Council
Funding Amount
$381,601.00
Summary
Pitcairn Island Language in the Diaspora. This project aims to expand knowledge of how different social environments affect language structure and use. It will analyse Pitkern, the Pitcairn Island language which is on the brink of extinction. It will supplement existing documentation of the language with that of its diaspora varieties in New Zealand and Australia. The outcomes will reveal the causes, processes and results of language change in Pitkern and create a foundation for comparison with ....Pitcairn Island Language in the Diaspora. This project aims to expand knowledge of how different social environments affect language structure and use. It will analyse Pitkern, the Pitcairn Island language which is on the brink of extinction. It will supplement existing documentation of the language with that of its diaspora varieties in New Zealand and Australia. The outcomes will reveal the causes, processes and results of language change in Pitkern and create a foundation for comparison with other island beach community languages.Read moreRead less
Creative innovation in a new digital economy. This project aims to investigate how the digital genre of the mobile webtoon is transforming media ecosystems in Australia, South Korea and America. While smartphone apps and platforms have enjoyed increasing global penetration since the late 2000s, there has been limited scholarly attention paid to interactions between webtoon artists, platforms, policymakers and global readers. The project will generate new knowledge about cross-media storytelling, ....Creative innovation in a new digital economy. This project aims to investigate how the digital genre of the mobile webtoon is transforming media ecosystems in Australia, South Korea and America. While smartphone apps and platforms have enjoyed increasing global penetration since the late 2000s, there has been limited scholarly attention paid to interactions between webtoon artists, platforms, policymakers and global readers. The project will generate new knowledge about cross-media storytelling, aesthetics and technologies by applying big data methods to analyse the production and reception of innovative mobile content. Through its case studies, the project will provide practical knowledge to Australian enterprises seeking to join the digital economy and capitalise on future opportunities in the global media environment.Read moreRead less