Reconfiguring intimate life: Gender and sexuality as sites of national redefinition in Australia since 1996. This project opens up current thinking about the nature of change in twenty-first century life in Australia by focusing on issues of gender and sexuality. It draws critical attention to a field of contest and re-negotiation of national identity and belonging, thus far not identified, that has far-reaching effects for the national fabric. It provides opportunities for thinking about sexual ....Reconfiguring intimate life: Gender and sexuality as sites of national redefinition in Australia since 1996. This project opens up current thinking about the nature of change in twenty-first century life in Australia by focusing on issues of gender and sexuality. It draws critical attention to a field of contest and re-negotiation of national identity and belonging, thus far not identified, that has far-reaching effects for the national fabric. It provides opportunities for thinking about sexual and reproductive relationships in ways that can be open to voices, stories and forms of belonging that signal a more generous, sustainable and healthy non-violent future.
The impact of the project will be on professional and scholarly training, teaching and research across a variety of disciplinary areas, as well as public debate. Read moreRead less
A project to examine and strengthen health care incident disclosure communication. Incidents occur frequently in health care, killing or maiming around 18,000 people per year. This study will map the experiences of patients and clinicians of conducting clinical incident discussions to enhance understanding of post-incident communication dynamics and develop models that facilitate incident communication.
Transnational Environmental Campaigns in the Australia-Asian Region. Conflict over environments, resources and landscapes has become a feature of contemporary political life. Increasingly, these conflicts are articulated, negotiated and potentially resolved across national boundaries and complex networks of media and communications. In the context of intensifying pressure for resource access, market opportunities and changing media practices in Australia and the Asian region, it is critical to e ....Transnational Environmental Campaigns in the Australia-Asian Region. Conflict over environments, resources and landscapes has become a feature of contemporary political life. Increasingly, these conflicts are articulated, negotiated and potentially resolved across national boundaries and complex networks of media and communications. In the context of intensifying pressure for resource access, market opportunities and changing media practices in Australia and the Asian region, it is critical to examine how competing environmental claims are mediated, and how this mediation influences public debate, policy and market viability. Providing evidence-based analysis of transnational conflicts as they emerge and travel, this project is expected to inform debate on Australia's environmental and economic sustainability.Read moreRead less
Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge mic ....Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge microscopy techniques to visualise whether the endogenous astrocyte protein metallothionein can promote regeneration in the injured nervous system of living zebrafish. The successful outcomes of this project will provide significant insight into understanding how the brain responds to injury.Read moreRead less
Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-th ....Investigating the molecular function of alpha-Haemoglobin stabilising protein. The research described in this proposal will provide new insights into haemoglobin regulation and redox chemistry in erythrocytes. Deregulation of these processes gives rise to a number of debilitating diseases, including varieties of anaemia and thalassaemia-in Australia it is estimated that 3% of the population could be carriers of b-thalassaemia mutations. Given the contribution of free aHb to the pathology of b-thalassaemia, understanding the specific aHb-binding factor, AHSP is a goal of national significance. In the long term, manipulation of AHSP function through gene therapy may have a direct role in the treatment of thalassaemia.Read moreRead less
Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These a ....Using metallothioneins as a model for understanding cellular and biochemical interactions between neurons and astrocytes within the brain. This research will reveal some of the changes that occur in the relationship between neurons and astrocytes as a consequence injury, aging or disease to the human brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or in neurodegenerative diseases. These are significant community issues in both economical and social terms. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest cellular processes associated with aging or disease of the brain, and will provide clues to promoting healthy aging.Read moreRead less
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
Plato's myth voice: the identification and interpretation of 'inspired speech' in plato. This project uses recent discoveries about the language of ancient myths, oracles and allegories to understand similar discourse in Plato and the Platonic tradition. It attempts to render such discourse intelligible to those who may not hear myths in the same context or share the same cultural background as Plato's listeners.
Revealing Enigma of Salt Bladders to Help Crops Cope with Salinity. In this project, the key transport systems mediating salt sequestration in halophytes are planned to be characterised and linked with cell genetic and metabolic profiles. Salinity is a major environmental hurdle affecting crop production around the world. Halophytes (naturally salt-loving plants) use specialised structures, called salt bladders, to sequester excessive salt outside their metabolically active parts. This feature i ....Revealing Enigma of Salt Bladders to Help Crops Cope with Salinity. In this project, the key transport systems mediating salt sequestration in halophytes are planned to be characterised and linked with cell genetic and metabolic profiles. Salinity is a major environmental hurdle affecting crop production around the world. Halophytes (naturally salt-loving plants) use specialised structures, called salt bladders, to sequester excessive salt outside their metabolically active parts. This feature is not utilised by crops however, and no information is available about the molecular mechanisms by which salt is pumped into bladder cells. This knowledge will allow breeders to utilise this, previously unexplored, trait to improve crop performance under conditions of salinity.Read moreRead less
Stomata functioning in halophytes for improved plant stress tolerance. This project aims to determine how halophytes balance photosynthesis and water loss under extreme soil conditions. Salinity and drought affect crop production. Plants’ ability to balance carbon dioxide uptake and water loss through stomata determines how they cope with stressors. Halophytes can achieve this balance at conditions that normally kill 99% of crops, but how they do so is unknown. This project will characterise the ....Stomata functioning in halophytes for improved plant stress tolerance. This project aims to determine how halophytes balance photosynthesis and water loss under extreme soil conditions. Salinity and drought affect crop production. Plants’ ability to balance carbon dioxide uptake and water loss through stomata determines how they cope with stressors. Halophytes can achieve this balance at conditions that normally kill 99% of crops, but how they do so is unknown. This project will characterise the transport systems mediating stomata function in halophytes and contribute to understanding the molecular and physiological basis of their operation. This should allow breeders to use this trait to improve crop performance under conditions of extreme salinity and drought.Read moreRead less