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Feeding and digestion in tropical rock lobster phyllosoma larvae and its applications for culture. Provision of larval culture diets that provide optimal nutrition in a suitable presentation format is the major challenge for developing a rock lobster aquaculture industry. Tropical rock lobsters are likely contenders due to their faster growth rates and shorter larval phase than temperate species. This project will assess the ingestive and digestive capabilities of larvae during development, thro ....Feeding and digestion in tropical rock lobster phyllosoma larvae and its applications for culture. Provision of larval culture diets that provide optimal nutrition in a suitable presentation format is the major challenge for developing a rock lobster aquaculture industry. Tropical rock lobsters are likely contenders due to their faster growth rates and shorter larval phase than temperate species. This project will assess the ingestive and digestive capabilities of larvae during development, through an examination of mouthpart and gut structure and their types and concentration of digestive enzymes. Information will be used to formulate and test improved diets of appropriate size, texture and nutritional composition and will be the first comprehensive analysis of preferred larval diets on the basis of their biological and physiological characteristics.Read moreRead less
Diversity and Defence: Characterisation of Extremely Variable Defensive Proteins from Sea Urchins. Antibiotic resistance is a global problem. In this project, we will study a new class of potential antibiotics - purpuratins - from sea urchins. Purpuratins are unique when compared to other antimicrobials because of their extreme structural diversity. By investigating that diversity, we will shed new light on biological methods for targeted drug design. This information will be critical to the de ....Diversity and Defence: Characterisation of Extremely Variable Defensive Proteins from Sea Urchins. Antibiotic resistance is a global problem. In this project, we will study a new class of potential antibiotics - purpuratins - from sea urchins. Purpuratins are unique when compared to other antimicrobials because of their extreme structural diversity. By investigating that diversity, we will shed new light on biological methods for targeted drug design. This information will be critical to the development of tailor-made antibiotics that are fine-tuned to kill particular micro-organisms. Our work represents a collaboration between researchers in Australia and the United States. It contributes directly to international scientific co-operation whilst providing high level training for young Australian researchers and students. Read moreRead less
Sugar transporters in coral symbiosis and origin of parasitism. We aim to identify how symbiotic algae feed sugar to their coral hosts. Corals need this algal sugar to exist, but no one knows how it is transferred, so understanding this crucial mechanism is hugely significant. The first benefit of this research will be a fundamental understanding about how two organisms (algae and coral) cooperate to build habitats like the Great Barrier Reef. We also aim to explore whether coral/algal coopera ....Sugar transporters in coral symbiosis and origin of parasitism. We aim to identify how symbiotic algae feed sugar to their coral hosts. Corals need this algal sugar to exist, but no one knows how it is transferred, so understanding this crucial mechanism is hugely significant. The first benefit of this research will be a fundamental understanding about how two organisms (algae and coral) cooperate to build habitats like the Great Barrier Reef. We also aim to explore whether coral/algal cooperation paved the way for the origin of parasitism. The second key outcome will be to identify the precise molecular mechanism that allowed parasitism to arise. This will benefit us through understanding the origins of important diseases such as human malaria and related infections of livestock and wildlife.
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The diversity and assembly of optics in nature. Optics, such as the design of new coloured reflectors, is a research strength for Australia. A reason for this is the potential for application - optical devices can be found far and wide in our everyday lives, from security devices on banknotes (holograms), to computer monitors (LCDs). An interesting parallel exists in nature - animals possess similar optical devices to those we use. So it makes sense to examine the animals' devices in a search fo ....The diversity and assembly of optics in nature. Optics, such as the design of new coloured reflectors, is a research strength for Australia. A reason for this is the potential for application - optical devices can be found far and wide in our everyday lives, from security devices on banknotes (holograms), to computer monitors (LCDs). An interesting parallel exists in nature - animals possess similar optical devices to those we use. So it makes sense to examine the animals' devices in a search for new reflectors, and that's an aim of this project. And since reflectors are often difficult to make, why not let animals make reflectors for us? That is a further aim of this project. Soon we may have genetically-altered butterfly scales embedded in our credit cards that cannot be counterfeited.Read moreRead less
Symbiotic partnership between algae and animals that powers coral reefs. This project aims to unlock the molecular basis of a partnership between a microscopic plant and an animal that powers coral growth. Most corals depend on microscopic algae living inside their bodies to nourish them. Most corals have to recruit new algae each time they reproduce, but only a particular strain of algae is accepted. This project aims to establish how anemones and corals identify and take in the right alga, how ....Symbiotic partnership between algae and animals that powers coral reefs. This project aims to unlock the molecular basis of a partnership between a microscopic plant and an animal that powers coral growth. Most corals depend on microscopic algae living inside their bodies to nourish them. Most corals have to recruit new algae each time they reproduce, but only a particular strain of algae is accepted. This project aims to establish how anemones and corals identify and take in the right alga, how the alga gives them food, and how the animal hosts regulate growth of their algae to optimise food production but avoid being overrun by algae. Understanding the partnership that drives reef growth and survival may better equip us to protect this threatened resource.Read moreRead less
Coral Reefs Sensing Our Changing Climate. Australia's Great Barrier Reef is a valuable national and community resource, supporting commercial and recreation fishing and extensive national and international tourism along the length of Queenslands coastline. However it is an environment that is under threat from changing climate. The impact of a degraded reef environment is broad reaching, with effects on the Australian and Queensland economy and way of life. A better understanding of how this va ....Coral Reefs Sensing Our Changing Climate. Australia's Great Barrier Reef is a valuable national and community resource, supporting commercial and recreation fishing and extensive national and international tourism along the length of Queenslands coastline. However it is an environment that is under threat from changing climate. The impact of a degraded reef environment is broad reaching, with effects on the Australian and Queensland economy and way of life. A better understanding of how this valuable environment will respond to its changing environment is imperative and will provide us with a more informed basis on which to predict its future sustainability. Read moreRead less
A lipodomic approach to cnidarian-dinoflagellate symbiosis. Fatty Acids are essential for human health and for reef health. This lipodomic study using newly developed techniques, aims to understand the essential and non-essential fatty acid metabolic exchange in the symbiosis that drives coral reef formation and health, and in turn gives reflective insight into our own metabolism.
Sleeping snails: investigating hypometabolism to reveal critical factors that aid life extension. The apparent state of eternal dormancy has fascinated people for hundreds of years. This project will explore new frontiers in life extension and snail control by defining those genes and peptides involved in snail hypometabolism. To achieve this, the project will interrogate the snails' natural state of hypometabolism called estivation.
Biosynthesis, folding and modification of conotoxins. Disulfide-rich peptides represent a diverse family of bioactive molecules which have been developed as drugs for the treatment of severe pain. This project seeks to understand their biosynthesis and how their functional diversity is generated. Such information will assist the translation of more of these novel peptides into new drugs.
Identifying novel insecticides and their targets: probing Australian arachnid venoms. Insect pests destroy an estimated 2-3 billion dollars of crops in Australia. Insect pests also are responsible for the transmission of many new and re-emerging human, animal and plant diseases threatening health, wellbeing and prosperity. Current insecticides are severely limited by toxicity and/or insect resistance, and some are undergoing use cancellation overseas. Thus there is an urgent need to develop safe ....Identifying novel insecticides and their targets: probing Australian arachnid venoms. Insect pests destroy an estimated 2-3 billion dollars of crops in Australia. Insect pests also are responsible for the transmission of many new and re-emerging human, animal and plant diseases threatening health, wellbeing and prosperity. Current insecticides are severely limited by toxicity and/or insect resistance, and some are undergoing use cancellation overseas. Thus there is an urgent need to develop safer and more specific insecticides that are effective against disease vectors and agricultural pest insects, as well as to identify new insecticide targets. This research has a multi-million dollar potential benefit to agricultural, health and pest control sectorsRead moreRead less