A Case-control Study Of Environment And Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$808,948.00
Summary
Breast cancer is the most common cancer in Australian women and there have been a number of recent events which have raised public concern that occupational exposures are contributing to the increasing occurrence of this cancer. In this study, we will investigate occupational causes of breast cancer, particularly shift work, industrial solvent use and combustion products. We will compare occupations of 1000 women with breast cancer and 2000 women without cancer.
Markers Of Androgen Action, Genetic Variation And Prostate Cancer Risk
Funder
National Health and Medical Research Council
Funding Amount
$798,907.00
Summary
This proposal aim to follow up evidence from a number of studies that genetic and non-genetic markers of hormonal action in different periods of a man's life are associated with prostate cancer risk using a collection of three large, independent epidemiologic studies on prostate cancer named the Prostate Cancer Program. A principal objective is to collect exposure data on acne and digit ratio, and genotype cases and controls across the studies of the Prostate Cancer Program for common genetic va ....This proposal aim to follow up evidence from a number of studies that genetic and non-genetic markers of hormonal action in different periods of a man's life are associated with prostate cancer risk using a collection of three large, independent epidemiologic studies on prostate cancer named the Prostate Cancer Program. A principal objective is to collect exposure data on acne and digit ratio, and genotype cases and controls across the studies of the Prostate Cancer Program for common genetic variants in 4 candidate genes in the hormonal pathway. The established risk factors for prostate cancer are only age, race and family history. We anticipate that this project will cast light on the role of hormones in prostate cancer and that we will identify new markers of risk of prostate cancer and markers of disease aggressiveness. These outcomes will help us identifying men who are at risk for prostate cancer to target screening and surveillance, and plan prevention strategies. Furthermore, they will also form the basis for research on treatment targets.Read moreRead less
The Impact of Enterprise Resource Planning Systems on Australian Organizations. Enterprise Resource Planning (ERP) implementation is one of the most pervasive sources of technological change in contemporary Australian enterprises. ERP systems are computer-based technologies that are designed to increase efficiency and achieve major cost savings across the entire organization. Their implementation has significant implications for the structure, nature and management of organizations. This project ....The Impact of Enterprise Resource Planning Systems on Australian Organizations. Enterprise Resource Planning (ERP) implementation is one of the most pervasive sources of technological change in contemporary Australian enterprises. ERP systems are computer-based technologies that are designed to increase efficiency and achieve major cost savings across the entire organization. Their implementation has significant implications for the structure, nature and management of organizations. This project's innovative application of an organizational change model to eight detailed case studies across a range of organizational types will generate important new insights into the effects of ERP implementations at Australian organizations and help explain why some implementations are more successful than others.Read moreRead less
Organisational performance during environmental uncertainty: The impact of an influential human resource function and high involvement work practices. Australians will benefit from the project because it will: 1) assist in the promotion of strategies that manage the productivity of critical talent at a time of environmental uncertainty; 2) promote a strategic rather than a reactive approach to the management of the Australian workforce at a time when companies may be pressured to take a short te ....Organisational performance during environmental uncertainty: The impact of an influential human resource function and high involvement work practices. Australians will benefit from the project because it will: 1) assist in the promotion of strategies that manage the productivity of critical talent at a time of environmental uncertainty; 2) promote a strategic rather than a reactive approach to the management of the Australian workforce at a time when companies may be pressured to take a short term view; 3) help to generate a positive workplace relations climate through the carriage of employee-focussed human resource management practices; and 4) provide guidance for the development of the competencies required for HRM professionals to add value for employees and for organisational performance.Read moreRead less
Managing age in organisational context: a comparative study of the meaning of age among managers. Australians are currently being encouraged to work longer to maximise their contribution to the economy but they often report there are organisational barriers to doing so. This study offers a new approach to understanding age focusing on managers and offers a framework of effective strategies for employers in managing age.
Risk and Change In Institutional Fields: The Case Of Industrial Chemicals. This project aims to explore how to manage risk through sustainable organisational strategies and institutional transformations. Chemical risks arise as by-products of economic and technological progress and can cause untold harm to human health and the environment. Using a discursive approach to compare how organisations in Australia and Canada manage chemical risks, this project aims to show how organisations can act as ....Risk and Change In Institutional Fields: The Case Of Industrial Chemicals. This project aims to explore how to manage risk through sustainable organisational strategies and institutional transformations. Chemical risks arise as by-products of economic and technological progress and can cause untold harm to human health and the environment. Using a discursive approach to compare how organisations in Australia and Canada manage chemical risks, this project aims to show how organisations can act as institutional entrepreneurs and introduce sustainable field-level solutions to risk, instead of relying on government regulation to deal with dangerous chemicals. The intended outcomes include the development of a model that identifies the challenges associated with three different risk scenarios – managing established risks, managing emerging risks and eliminating risks – as well as identifying and evaluating strategies to address these challenges.Read moreRead less
An organizational perspective on risk assessment: comparing chemicals management in Australia and Canada. The project compares the managerial and organisational implications of chemical risk assessment in Australia and Canada. It will identify how governments can effectively manage the relationships among different stakeholder organisations involved in risk assessment; and explore how different cultural contexts influence risk assessment.
Advancing the theoretical bases of supply chain management through the lens of relational exchange theory. This project will explain and predict the behaviour of supply chain members better than current theories do. An integrated theory of supply chain management will be developed and tested empirically. This theory will enable better understanding of how supply chains function and guide actions of managers so that the expected benefits are realised.
Managing human resources in an advanced economy from the perspective of emerging Chinese multinationals: the case of NWII in Australia. This project will investigate human resource management practices in the resources sector in Australia and China. The outcomes of this study will provide important theoretical and operational insights into Chinese foreign direct investment for stakeholders such as the Australian government, community, employees and their representatives.
Planning for the adaptive management of wetland rehabilitation; Kanyapella Basin Case Study. Australia's ephemeral wetlands are being lost or degraded primarily through drainage. There is a pressing need to conserve the ecological character of remaining systems, and rehabilitate degraded ones. Rehabilitation is invariably constrained by water availability, community expectations and uncertainty about ecosystem responses to different water regimes. This project applies the adaptive management mod ....Planning for the adaptive management of wetland rehabilitation; Kanyapella Basin Case Study. Australia's ephemeral wetlands are being lost or degraded primarily through drainage. There is a pressing need to conserve the ecological character of remaining systems, and rehabilitate degraded ones. Rehabilitation is invariably constrained by water availability, community expectations and uncertainty about ecosystem responses to different water regimes. This project applies the adaptive management model to wetland rehabilitation. Adaptive management addresses uncertainty through experiments integrated into the rehabilitation process. It uses monitoring, and information feedback loops to inform current management actions. A generic model for the adaptive management of wetland rehabilitation will be developed which will predict responses to different re-wetting scenarios.Read moreRead less