Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia ....Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia from invasive diseases. There is an urgency to undertake our research because global environmental change and increasing movements of people (particularly military personnel) from overseas regions where these diseases are endemic is increasing the vulnerability of northern Australia to the (re)establishment of mosquito borne diseases.Read moreRead less
The Tasmanian Healthy Brain Project: A Longitudinal Intervention Study To Reduce The Risk Of Ageing-related Cognitive Decline And Dementia
Funder
National Health and Medical Research Council
Funding Amount
$878,792.00
Summary
It has been proposed that engagement in purposeful complex mental stimulation provides protection against dementia. The Tasmanian Healthy Brain Project (THBP) is a unique, large-scale prospective trial that examines whether university-level study in older adult population reduces ageing-related cognitive decline and risk of dementia. This project will also examine how an individual’s genetic profile may influence the potential benefits of complex mental stimulation as well as risk of dementia.
The endangered swift parrot as a model for managing small migratory birds. Endangered swift parrots use variable locations while breeding in eastern Tasmania and over winter on the Australian mainland. This project aims to develop effective conservation strategies for swift parrots and other migrants using new and long term data and innovative technological solutions to tracking small birds across vast landscapes.
Integrating fire and predator management to conserve threatened species. This project aims to empower land managers to better conserve Australia’s threatened native animals by developing decision-support approaches that facilitate integrated management of threatening processes. The project will use a combination of novel predictive models, field experiments and data syntheses to assist land managers to better conserve Australia’s threatened native fauna. This project will benefit biodiversity co ....Integrating fire and predator management to conserve threatened species. This project aims to empower land managers to better conserve Australia’s threatened native animals by developing decision-support approaches that facilitate integrated management of threatening processes. The project will use a combination of novel predictive models, field experiments and data syntheses to assist land managers to better conserve Australia’s threatened native fauna. This project will benefit biodiversity conservation by enabling more effective allocation of limited conservation resources.Read moreRead less
How isolated is Antarctica? Assessing past and present plant colonisations. The project aims to assess how biologically isolated Antarctica is by discovering how, when and where natural colonisations of the continent have occurred. The research will focus on mosses, the dominant plant group in the Antarctic. genomic tools will be combined with environmental, spatial, and ecological data to assess mechanisms and directions of dispersal to and around Antarctica, and to predict areas most likely to ....How isolated is Antarctica? Assessing past and present plant colonisations. The project aims to assess how biologically isolated Antarctica is by discovering how, when and where natural colonisations of the continent have occurred. The research will focus on mosses, the dominant plant group in the Antarctic. genomic tools will be combined with environmental, spatial, and ecological data to assess mechanisms and directions of dispersal to and around Antarctica, and to predict areas most likely to be colonised in the future. This will help understand the processes underpinning the evolution and diversity of Antarctic species, and the vulnerability and adaptability of Antarctic ecosystems. Read moreRead less
Clothes, fibres and filters that reduce pollution by micro and nano debris. This project aims to provide scientifically verified methods to avoid, intercept and redesign products that cause the most abundant type of marine plastic pollution – clothing fibres - which has increased by over 450% in 60 years. It will determine how natural and plastic fibres, clothing brands and washing machine filters, alter fibre emissions and ecological impacts. This will enable protocols to improve products and t ....Clothes, fibres and filters that reduce pollution by micro and nano debris. This project aims to provide scientifically verified methods to avoid, intercept and redesign products that cause the most abundant type of marine plastic pollution – clothing fibres - which has increased by over 450% in 60 years. It will determine how natural and plastic fibres, clothing brands and washing machine filters, alter fibre emissions and ecological impacts. This will enable protocols to improve products and the environment, and reduce health risks that will benefit the public, government regulation and companies in designing "eco-friendly" products.Read moreRead less
Fostering school attendance for students in Out-of-Home Care. This project aims to investigate why children and young people in Out-Of-Home-Care in Australia are absent from school far more than their peers. The project expects to generate new knowledge about the reasons for their absences and to develop solutions to improve attendance through: children’s own voices; detailed absence data; policy audit; and case studies of promising practice. Expected outcomes include a comprehensive conceptuali ....Fostering school attendance for students in Out-of-Home Care. This project aims to investigate why children and young people in Out-Of-Home-Care in Australia are absent from school far more than their peers. The project expects to generate new knowledge about the reasons for their absences and to develop solutions to improve attendance through: children’s own voices; detailed absence data; policy audit; and case studies of promising practice. Expected outcomes include a comprehensive conceptualisation of absences including those triggered by schools or the care context; and an evidence-informed, child-centred framework to enable attendance and, thereby, improved educational outcomes. This should provide significant social and economic benefits both for children in care and for the community. Read moreRead less
Mammal declines in northern Australia: science for conservation and recovery. Australia’s unique mammal fauna is a rich biological heritage for the nation. It provides a wealth of ecosystem services, and many mammal species have special cultural or aesthetic value. However, our mammals are sadly depleted, and we already have the worst record of recent mammal extinction of any nation. Preventing further mammal extinctions, and managing environments to allow declined mammals to recover, will be of ....Mammal declines in northern Australia: science for conservation and recovery. Australia’s unique mammal fauna is a rich biological heritage for the nation. It provides a wealth of ecosystem services, and many mammal species have special cultural or aesthetic value. However, our mammals are sadly depleted, and we already have the worst record of recent mammal extinction of any nation. Preventing further mammal extinctions, and managing environments to allow declined mammals to recover, will be of great benefit to Australian biodiversity and to the ecosystem processes and human values that depend on it.Read moreRead less