CARDIAC-ARIA : Measuring the accessibility to cardiovascular services in rural and remote Australia via applied geographical spatial technology (GIS). Despite significant improvements in the cardiovascular health of Australians, Cardiovascular Disease (CVD) continues to impose a heavy burden on Australians in terms of cost,disability and death. Recent evidence suggests that mortality from CVD increases with increasing remoteness. Rates are reported to be between 20% and 50% higher in rural areas ....CARDIAC-ARIA : Measuring the accessibility to cardiovascular services in rural and remote Australia via applied geographical spatial technology (GIS). Despite significant improvements in the cardiovascular health of Australians, Cardiovascular Disease (CVD) continues to impose a heavy burden on Australians in terms of cost,disability and death. Recent evidence suggests that mortality from CVD increases with increasing remoteness. Rates are reported to be between 20% and 50% higher in rural areas compared to major cities. This project, with its extensive use of Geographic Information Systems (GIS) technology, will rank 11,338 rural and remote population centres to identify geographical 'hotspots' where there is likely to be a mismatch between the demand for and actual provision of cardiovascular services.Read moreRead less
Biophysical identification of natural human antibody targets. A natural human antibody, PAT-SM6, isolated using technology developed by the partner organisation (Patrys), offers promise as a therapy to reduce mortalities due to cancer, the leading cause of death in Australia. The novelty of the approach pioneered by Patrys is the direct production of human antibodies which avoids undesirable side effects associated with the use of antibodies containing non-human components. This project is to ....Biophysical identification of natural human antibody targets. A natural human antibody, PAT-SM6, isolated using technology developed by the partner organisation (Patrys), offers promise as a therapy to reduce mortalities due to cancer, the leading cause of death in Australia. The novelty of the approach pioneered by Patrys is the direct production of human antibodies which avoids undesirable side effects associated with the use of antibodies containing non-human components. This project is to discover the specificity of PAT-SM6 for proteins and protein complexes and how these interactions lead to tumour cell death. This work will enhance the effectiveness of human antibody therapies and help in the development of this fast growing area within the biotechnology industry in Australia.Read moreRead less