Bioreactors for manufacture of human platelets. Blood cell transfusion is a critical part of medicine that is supported by volunteer donors. Unfortunately, the demand for blood cells for transfusion far outstrips supply and therefore new strategies are required for manufacture of blood cells. This project will lead to the development of technology for manufacture of human platelets from stem cells. The systems devised will be applicable to a broad range of other blood cell types.
Mimetics and small chemical compounds for hemopoietic stem cell mobilisation. This project will result in the design and synthesis of new chemical compounds that could be used clinically to help collect blood stem cells for bone marrow transplantation. For patients this will mean more effective and less painful ways to collect stem cells and better transplant outcomes. There is a large, ongoing international market for this type of drug and likelihood of significant financial benefit.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100043
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Development of an ultra-high speed spinning disk confocal micro-particle image velocimetry (PIV) platform for the investigation of cardiovascular disease . This facility will establish a microscope system specifically designed to investigate the function of blood cells in the context of cardiovascular diseases such as heart attack and stroke.
CARDIAC-ARIA : Measuring the accessibility to cardiovascular services in rural and remote Australia via applied geographical spatial technology (GIS). Despite significant improvements in the cardiovascular health of Australians, Cardiovascular Disease (CVD) continues to impose a heavy burden on Australians in terms of cost,disability and death. Recent evidence suggests that mortality from CVD increases with increasing remoteness. Rates are reported to be between 20% and 50% higher in rural areas ....CARDIAC-ARIA : Measuring the accessibility to cardiovascular services in rural and remote Australia via applied geographical spatial technology (GIS). Despite significant improvements in the cardiovascular health of Australians, Cardiovascular Disease (CVD) continues to impose a heavy burden on Australians in terms of cost,disability and death. Recent evidence suggests that mortality from CVD increases with increasing remoteness. Rates are reported to be between 20% and 50% higher in rural areas compared to major cities. This project, with its extensive use of Geographic Information Systems (GIS) technology, will rank 11,338 rural and remote population centres to identify geographical 'hotspots' where there is likely to be a mismatch between the demand for and actual provision of cardiovascular services.Read moreRead less