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Culture-independent Assessment Of The Microbiota Underlying Chronic Suppurative Lung Disease In Indigenous Children.
Funder
National Health and Medical Research Council
Funding Amount
$310,071.00
Summary
Chronic suppurative lung disease (CSLD) affects 1 in 68 Indigenous children in the Northern Territory. The condition leads to loss of lung function which reduces life-expectancy. Little is known about microbial factors underlying the disease. My research uses DNA-based methods to describe lower airway microbiology of CSLD affecting Indigenous children, including investigation of bacteria, viruses and biofilm. Better understanding of the microbiology will potentially lead to development of improv ....Chronic suppurative lung disease (CSLD) affects 1 in 68 Indigenous children in the Northern Territory. The condition leads to loss of lung function which reduces life-expectancy. Little is known about microbial factors underlying the disease. My research uses DNA-based methods to describe lower airway microbiology of CSLD affecting Indigenous children, including investigation of bacteria, viruses and biofilm. Better understanding of the microbiology will potentially lead to development of improved treatments.Read moreRead less
Effects Of Antibiotics, Vaccines And Environment On The Population Biology Of Bacterial Respiratory Pathogens In Australian Indigenous Children – A Synthesis Of Studies
Funder
National Health and Medical Research Council
Funding Amount
$316,449.00
Summary
For over 20 years researchers in the Northern Territory have studied middle ear and lower respiratory infections which severely affect Indigenous children. Projects have included antibiotic and vaccine interventions, however disease rates remain high. Much has been learned about the bacteria causing these infections and the effects of interventions. This study will synthesise these findings, and explore environmental influences, to further inform prevention and treatment strategies.