A New Direction For TB Control In Highly Endemic Countries: A RCT Of Active Case Finding
Funder
National Health and Medical Research Council
Funding Amount
$1,362,910.00
Summary
Tuberculosis is the number 1 health problem in Vietnam . Many people with TB do not know they have the disease but are infectious to others. Hence, the disease continues to spread. This project will investigate the role of x-ray screening to detect and treat more people with TB, particularly those who do not have symptoms. This may be an important element of future TB control programs in Vietnam and elsewhere in our region.
Determining The Impact Of Opioid Substitution Therapy Upon Mortality And Recidivism Among Prisoners: A 22-year Data Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$354,114.00
Summary
This study will quantify the impact of opioid substitution therapy (OST; methadone or buprenorphine) on two important outcomes for opioid dependent prisoners: mortality, particularly in the post-release period; and subsequent criminal activity. The study will have almost 600,000 person-years of follow-up over 22 years, allowing fine grained analyses of disadvantaged subpopulations. The study has clear implications for the health of this population, crime reductions, and cost savings.
A Randomized Clinical Trial Comparing Effectiveness Of 4RIF And 9INH For Treatment Of Latent TB Infection
Funder
National Health and Medical Research Council
Funding Amount
$496,875.00
Summary
Treatment of latent tuberculosis infection (LTBI) is one intervention that is known to prevent the occurrence of active TB. Current treatment is based on a six to nine month course of isoniazid. The treatment has side effects in some people and many people do not complete the treatment. The present study is to test an alternative treatment regimen (4 months of rifampicin) which has fewer side-effects and is more likely to be completed.