Managing an ageing population for income adequacy and fiscal sustainability. This project aims to improve understanding of the impacts of existing key reforms intended to ease fiscal pressures associated with population ageing. The right mix of retirement income policies is vital to Australia's fiscal sustainability, however the effectiveness of existing policies is unknown. The project expects to identify impacts of key reforms on employment, re-training, income, savings and future retirement i ....Managing an ageing population for income adequacy and fiscal sustainability. This project aims to improve understanding of the impacts of existing key reforms intended to ease fiscal pressures associated with population ageing. The right mix of retirement income policies is vital to Australia's fiscal sustainability, however the effectiveness of existing policies is unknown. The project expects to identify impacts of key reforms on employment, re-training, income, savings and future retirement income and public pension receipt. The project will develop a new tax records-based dataset to facilitate future research on tax and welfare systems.Read moreRead less
Insecure Work and the Mental Health of Workers and their Families. This project aims to explore the relationship between insecure work and mental health by applying advanced econometric methods to large survey and administrative datasets, and newly collected survey data. This project expects to provide causal policy-relevant estimates of how insecure work is affecting the wellbeing of workers and their families, and for whom the effects are most harmful. It also expects to inform on how poor men ....Insecure Work and the Mental Health of Workers and their Families. This project aims to explore the relationship between insecure work and mental health by applying advanced econometric methods to large survey and administrative datasets, and newly collected survey data. This project expects to provide causal policy-relevant estimates of how insecure work is affecting the wellbeing of workers and their families, and for whom the effects are most harmful. It also expects to inform on how poor mental health influences the types of jobs that people enter into. This should provide significant benefits, including evidence needed to improve existing workplace and employment programs, and evidence ensuring that assistance is efficiently targeted to those workers and industries with the greatest need.Read moreRead less
GENETIC PREDICTION OF FRACTURE IN A RISK-STRATIFIED POPULATION
Funder
National Health and Medical Research Council
Funding Amount
$363,000.00
Summary
Osteoporosis is a condition characterised by excessive bone loss and impaired bone quality, which ultimately results in fracture with minimal trauma. Osteoporosis affects 27% of women and 11% of men aged 60 years or above in the community, and costs Australia around $7 billion each year. Individuals with low bone mineral density (BMD) have a significantly higher risk of fracture than those with normal BMD. In the long-term (14-year) Dubbo Osteoporosis Epidemiology Study, more than half of indivi ....Osteoporosis is a condition characterised by excessive bone loss and impaired bone quality, which ultimately results in fracture with minimal trauma. Osteoporosis affects 27% of women and 11% of men aged 60 years or above in the community, and costs Australia around $7 billion each year. Individuals with low bone mineral density (BMD) have a significantly higher risk of fracture than those with normal BMD. In the long-term (14-year) Dubbo Osteoporosis Epidemiology Study, more than half of individuals with osteoporosis (e.g., low BMD) did not sustain a fracture, while approximately 60% of fracture cases had BMD above the high risk levels. Thus, BMD alone is not a good discriminant of fracture versus non-fracture cases. It is widely known that the liability to fracture is determined in part by genes. Previous studies, including from our group, have suggested a number of candidate genes that are associated with fracture risk. The fundamental issue that this study is concerned is that how and whether genetic markers could be used to facilitate case finding. It is proposed that common variations of certain genes are associated with fracture risk independent of BMD. That is, they can identify individuals at relatively high and low fracture risk after stratification for BMD. Hence, some markers may identify those individuals likely (and unlikely) to fracture even with low (osteoporotic) BMD. Similarly, some, possibly the same, markers may identify individuals at high risk of fracture despite relatively good (ie non-osteoporotic) BMD. It is further proposed that no single gene will achieve this outcome, but rather a small set of such gene polymorphisms will provide clinically useful risk information. This effect is entirely analogous to the use of clinical risk indicators (eg, age, weight, sex, family history, etc) to assess the risk of future fracture.Read moreRead less
Myeloma Plasma Cell Dormancy - 'Eradicating The Sleeping Giant'
Funder
National Health and Medical Research Council
Funding Amount
$834,428.00
Summary
Multiple myeloma is a fatal cancer that develops in the skeleton. Current therapies are initially effective, but patients develop resistance and the disease returns. This makes the search for drugs to overcome resistance a priority. Myeloma cells can hide in bone in a dormant state where they are insensitive to chemotherapy. We have identified new drug targets in dormant cells. We are investigating whether these new targets can be used eradicate myeloma cells and cure the disease.
Living on the Margin: The Relationship between Mental Health and Work in Australia. This project will assess the relationship between Australians' mental health and their work, for example, employment status, work conditions and hours. The study is the first to exploit the detailed timing of mental health and employment transitions to identify whether poor labour market outcomes lead to poor mental health or whether the reverse is true. New Australian data will be used to understand whether the ....Living on the Margin: The Relationship between Mental Health and Work in Australia. This project will assess the relationship between Australians' mental health and their work, for example, employment status, work conditions and hours. The study is the first to exploit the detailed timing of mental health and employment transitions to identify whether poor labour market outcomes lead to poor mental health or whether the reverse is true. New Australian data will be used to understand whether the link between mental health and work adds to the economic vulnerability of families and those at risk of homelessness. The results will advance our understanding of the way that mental health affects overall economic well-being and will inform current policy initiatives to promote economic participation and good mental health.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100079
Funder
Australian Research Council
Funding Amount
$411,918.00
Summary
Anisotropic single-particle transducers. The project aims to tackle a major challenge in techniques that manipulate tiny particles – increasing the performance of transducer devices that convert magnetic forces to mechanical movement. It will centre on interactions on the surface of particular particles, bypassing a known scientific limit. Expected outcomes include a fundamental understanding of key factors that have recently been shown to enhance magnetic responsivity and efficient mechanical m ....Anisotropic single-particle transducers. The project aims to tackle a major challenge in techniques that manipulate tiny particles – increasing the performance of transducer devices that convert magnetic forces to mechanical movement. It will centre on interactions on the surface of particular particles, bypassing a known scientific limit. Expected outcomes include a fundamental understanding of key factors that have recently been shown to enhance magnetic responsivity and efficient mechanical manipulation and sensing in a magnetic field. The project outcomes will benefit developers by, for example, advanced nanoscale devices for robotics, sensing and molecular bioassays; controlling biophysical processes; and fundamental mechanobiology research.Read moreRead less
Complex and nonlinear pattern analysis in architectural space, form and program: developing computational tools to support social and cultural design. In a country that is experiencing increasing urban density there is an urgent need for the development of tools and models for the production of socially and culturally responsive environments. The Fellowship develops a new quantitative and qualitative understanding of the experiential and semiotic characteristics of buildings. The project, assis ....Complex and nonlinear pattern analysis in architectural space, form and program: developing computational tools to support social and cultural design. In a country that is experiencing increasing urban density there is an urgent need for the development of tools and models for the production of socially and culturally responsive environments. The Fellowship develops a new quantitative and qualitative understanding of the experiential and semiotic characteristics of buildings. The project, assisted by developments in robotics technology, produces a leading-edge computational model for analysing complex and non-linear patterns in architectural space, form and program from a social and cultural perspective. Such a model will assist design practitioners, scholars, town planners and policy writers to shape rich, responsive and inclusive architectural environments.Read moreRead less
Human Capital, Cognitive Skills and Labour Market Outcomes. As Australia competes in the ‘educational race,’ this project will generate new knowledge on the relationship between education, skill attainment and economic outcomes in Australia. The research will provide new empirical evidence on cognitive and non-cognitive skills formation over the life-cycle, and the relationship between these skills and labour market outcomes in Australia within the broader international context. The research wil ....Human Capital, Cognitive Skills and Labour Market Outcomes. As Australia competes in the ‘educational race,’ this project will generate new knowledge on the relationship between education, skill attainment and economic outcomes in Australia. The research will provide new empirical evidence on cognitive and non-cognitive skills formation over the life-cycle, and the relationship between these skills and labour market outcomes in Australia within the broader international context. The research will advance methodological techniques for the economic analysis of cognitive skills and their economic impacts. The research will inform public policy formulation relating to educational attainment, skill development, and strategies to encourage longer workforce engagement over the life-cycle.Read moreRead less
Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions w ....Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions will be re-evaluated in the context of contemporary economic, social and environmental criteria to enable existing multi-criteria models to deliver more sustainable outcomes that are also feasible and in the national interest, and consequently minimise the industry's current exposure to future climate change.Read moreRead less