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New strategies for highly sensitive chemical detection based on luminescent ruthenium and iridium complexes. Chemical reactions that emit tiny quantities of light, not even visible to the naked eye, can be used to detect the biomarkers of disease or traces of chemical or biological weapons in a terrorist attack. This project creates a new generation of reagents for this remarkably sensitive mode of detection for these and other important applications.
3D printed microchemical devices and systems. This project aims to address the barriers faced by 3D printing in chemistry. 3D printing can create bespoke 3D structures within a fraction of time and cost compared to traditional fabrication. However, its scope in chemistry has been limited by the poor chemical robustness, biotoxicity and low resolution of the 3D printed components. Hence, this project will develop novel gold coating techniques and explore high-resolution 3D printing to overcome th ....3D printed microchemical devices and systems. This project aims to address the barriers faced by 3D printing in chemistry. 3D printing can create bespoke 3D structures within a fraction of time and cost compared to traditional fabrication. However, its scope in chemistry has been limited by the poor chemical robustness, biotoxicity and low resolution of the 3D printed components. Hence, this project will develop novel gold coating techniques and explore high-resolution 3D printing to overcome these challenges. The project should generate commercially significant products (analytical platforms), technology (gold coating) and patents. The developed systems and technologies will address Australian research challenges in advanced manufacturing and enable on-site environmental monitoring.Read moreRead less
The pollution potential of mercury in legacy biosolids and possibilities for its minimisation by phytoremediation and phytostabilisation approaches. This project will develop: (1) new chemical analysis techniques to study the mercury fate in legacy biosolids which will lead to better understanding of their potential environmental impact; (2) environmentally-benign phytoremediation approaches using native plants to reduce mercury release so the biosolids can be safely used for land applications.
Improved cryopreservation protocols for long term storage of platelets. The aim of this project is to characterise human blood platelet deterioration during cold storage and cryopreservation, and accelerate the development of improved long-term storage options. The project expects to generate important new knowledge about how platelets deteriorate during storage, and how such deterioration can be minimized. The expected outcomes are improved methods for long term platelet storage. This should be ....Improved cryopreservation protocols for long term storage of platelets. The aim of this project is to characterise human blood platelet deterioration during cold storage and cryopreservation, and accelerate the development of improved long-term storage options. The project expects to generate important new knowledge about how platelets deteriorate during storage, and how such deterioration can be minimized. The expected outcomes are improved methods for long term platelet storage. This should benefit blood donation services and hospitals by improving platelet delivery to remote locations, reducing wasted blood and the number of donations required, leading to significant financial savings.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101635
Funder
Australian Research Council
Funding Amount
$343,450.00
Summary
DNA origami functionalised nanoscale surfaces. This project aims to combine the strengths of top-down and bottom-up nanofabrication to build hybrid structures. In traditional top-down nanofabrication, large systems pattern a semiconductor substrate to build up sophisticated devices. In contrast, in the emerging field of bottom-up nanotechnology, clever design of molecular interactions drives the self-assembly of smaller building blocks into more complex structures, with smaller features. This pr ....DNA origami functionalised nanoscale surfaces. This project aims to combine the strengths of top-down and bottom-up nanofabrication to build hybrid structures. In traditional top-down nanofabrication, large systems pattern a semiconductor substrate to build up sophisticated devices. In contrast, in the emerging field of bottom-up nanotechnology, clever design of molecular interactions drives the self-assembly of smaller building blocks into more complex structures, with smaller features. This project aims to bridge the gap between these two technologies to build functional devices. These devices will be applied, for example, to understand biological problems such as why blood clots form on implanted medical devices - their main cause of failure.Read moreRead less