Benign fabrication of microfluidic hydrogel for improved artificial vasculature in bone implants. We will create a benign technology for synthesising microfluidic hydrogels to generate artificial vascultures in bone implants. It is a critical step to enable the use of tissue-engineered vital organs, such as bone, heart and kidney in patients with end-stage organ failure. Thicker scaffolds will be possible, as the vasculature will provide nutrients and oxygen for cells to grow into 3D scaffolds. ....Benign fabrication of microfluidic hydrogel for improved artificial vasculature in bone implants. We will create a benign technology for synthesising microfluidic hydrogels to generate artificial vascultures in bone implants. It is a critical step to enable the use of tissue-engineered vital organs, such as bone, heart and kidney in patients with end-stage organ failure. Thicker scaffolds will be possible, as the vasculature will provide nutrients and oxygen for cells to grow into 3D scaffolds. It will promote capacity of Australia for manufacturing global biomaterial products for tissue engineering. We will also develop in-situ imaging analytical protocols for the rapid analysis of broad arrays of functional molecules, with significant bearing on BioMEMS design to develop methods for diagnosis of fatal diseases.Read moreRead less
Application of bioreactors for culture of differentiated cells and solid-phase tissues. The aim of this project is to develop methods for producing three-dimensional human cartilage outside of the body. Tissue-engineered cartilage has a range of applications, including in toxicity testing, for production of therapeutics, and as surgical transplant devices. Bioreactors will be used to culture cartilage under controlled conditions for development of living tissues with properties as close as possi ....Application of bioreactors for culture of differentiated cells and solid-phase tissues. The aim of this project is to develop methods for producing three-dimensional human cartilage outside of the body. Tissue-engineered cartilage has a range of applications, including in toxicity testing, for production of therapeutics, and as surgical transplant devices. Bioreactors will be used to culture cartilage under controlled conditions for development of living tissues with properties as close as possible to those of native articular cartilage. Novel culture strategies will be used to enhance the availability of growth factors and provide adequate oxygen and nutrient exchange. These techniques have the potential to yield significant improvements in the quality of engineered cartilage.Read moreRead less
Advanced technology for production of foreign proteins in plant cell and organ cultures. The aim of this project is to develop new technology for in vitro production of pharmaceutical proteins using plant tissue culture. Animal proteins such as antibodies are currently being produced using recombinant plant systems in bioreactors; however, transient gene expression using genetically-modified viruses has a range of potential benefits for substantially increasing foreign protein titres. Because vi ....Advanced technology for production of foreign proteins in plant cell and organ cultures. The aim of this project is to develop new technology for in vitro production of pharmaceutical proteins using plant tissue culture. Animal proteins such as antibodies are currently being produced using recombinant plant systems in bioreactors; however, transient gene expression using genetically-modified viruses has a range of potential benefits for substantially increasing foreign protein titres. Because viruses rapidly infect plant tissues and can be amplified to extremely high levels, this new method for in vitro foreign protein synthesis has considerable promise. This project will extend the existing science of plant tissue culture into new areas with commercial potential.Read moreRead less
Engineering of cartilage-based biomaterials under dynamic culture conditions. This work contributes to the development of advanced technologies in the area of biomaterials. The cartilage biomaterials generated in this work will lead to new medical applications in tissue reconstruction and replacement, which is of direct benefit to society by improving the methods used to treat joint disease and injury. As there is a significant commercial market for tissue-engineered cartilage products, this res ....Engineering of cartilage-based biomaterials under dynamic culture conditions. This work contributes to the development of advanced technologies in the area of biomaterials. The cartilage biomaterials generated in this work will lead to new medical applications in tissue reconstruction and replacement, which is of direct benefit to society by improving the methods used to treat joint disease and injury. As there is a significant commercial market for tissue-engineered cartilage products, this research also has implications for enhancing the scope and profitability of the Australian biotechnology industry. The project will be a vehicle for research training in a broad range of interdisciplinary areas. Students involved in the work will be equipped with a versatile and valuable combination of skills.Read moreRead less
Simultaneous dissolved methane and nitrogen removal. Direct anaerobic treatment of wastewater converts majority of organic matters in wastewater to methane, an energy source. However, up to 50% of the methane produced stays dissolved in wastewater. Its subsequent stripping to atmosphere in aerobic treatment not only causes significant loss of energy but also emission of a potent greenhouse gas. This project aims to develop a technology that not only avoids methane stripping but also enables its ....Simultaneous dissolved methane and nitrogen removal. Direct anaerobic treatment of wastewater converts majority of organic matters in wastewater to methane, an energy source. However, up to 50% of the methane produced stays dissolved in wastewater. Its subsequent stripping to atmosphere in aerobic treatment not only causes significant loss of energy but also emission of a potent greenhouse gas. This project aims to develop a technology that not only avoids methane stripping but also enables its beneficial use to enhance nitrogen removal, which is otherwise typically unsatisfactory due to the lack of organic carbon to support denitrification. The project will provide strong support to the Australian water industry in their endeavour to achieve energy- and carbon-neutral wastewater services.Read moreRead less
Very thin, highly oriented and featured diamond films. The technology for making very thin diamond films, having sculpted surface features and fabricated from tiny and highly oriented individual diamond crystallites, would enable widespread potential applications, including eg surface acoustic wave devices, optical biosensors for ?lab-on-a-chip?, and field emitter arrays for paper thin, bright and wide angle flat panel displays, amongst others. Diamond is uniquely suited to these applications, ....Very thin, highly oriented and featured diamond films. The technology for making very thin diamond films, having sculpted surface features and fabricated from tiny and highly oriented individual diamond crystallites, would enable widespread potential applications, including eg surface acoustic wave devices, optical biosensors for ?lab-on-a-chip?, and field emitter arrays for paper thin, bright and wide angle flat panel displays, amongst others. Diamond is uniquely suited to these applications, and the capability to manipulate film properties and features which is the key requirement, is within grasp.Read moreRead less
Production of hydrogen from biomass by integrated catalytic aqueous hydrolysis and reforming in subcritical water. The outcomes of this project will lead to the development of a novel process for efficient and cost-effective hydrogen production from renewable biomass using integrated hydrolysis and catalytic aqueous reforming at low temperatures. Such technological innovation will provide significant benefits to Australia as a whole for transition to a truly sustainable hydrogen economy. The nov ....Production of hydrogen from biomass by integrated catalytic aqueous hydrolysis and reforming in subcritical water. The outcomes of this project will lead to the development of a novel process for efficient and cost-effective hydrogen production from renewable biomass using integrated hydrolysis and catalytic aqueous reforming at low temperatures. Such technological innovation will provide significant benefits to Australia as a whole for transition to a truly sustainable hydrogen economy. The novel reaction system and research methodologies proposed in this proposal will certainly enhance Australia's science and technology capability and international competitiveness, in the area of reaction engineering. Also of the national benefit is the successful training of a postgraduate at PhD level who will no doubt add to future scientific research workforce.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100952
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
A chemical looping process for carbon fibre production from plastics. This project aims to develop Mineral Looping Plastic Reforming (MLPR), a chemical looping reforming process for tonnage production of carbon nanofibers from plastic waste. This efficient process uses naturally occurring minerals (limestone, dolomite and ilmenite) to convert plastic waste to carbon nanofibers. The project will research the inner working of the MLPR process and the reforming reactions of plastics in the presence ....A chemical looping process for carbon fibre production from plastics. This project aims to develop Mineral Looping Plastic Reforming (MLPR), a chemical looping reforming process for tonnage production of carbon nanofibers from plastic waste. This efficient process uses naturally occurring minerals (limestone, dolomite and ilmenite) to convert plastic waste to carbon nanofibers. The project will research the inner working of the MLPR process and the reforming reactions of plastics in the presence of naturally occurring mineral mixtures. This project is expected to make Australia a leader in waste use, facilitate the uptake of abundant waste streams to produce high value products, and resolve sustainability, energy and environmental issues in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775513
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Advanced Process Tomography Research Facility for Multiphase System Studies. The establishment of an advanced process tomography facility at UNSW has several important national benefits, including; increased capacity of the collaborating institutions to train highly qualified personnel to meet new and growing demands in the processing industries; the transfer of research-based cheap and efficient technologies to our industries to enhance their position in a competitive global market; the improve ....Advanced Process Tomography Research Facility for Multiphase System Studies. The establishment of an advanced process tomography facility at UNSW has several important national benefits, including; increased capacity of the collaborating institutions to train highly qualified personnel to meet new and growing demands in the processing industries; the transfer of research-based cheap and efficient technologies to our industries to enhance their position in a competitive global market; the improvement in our culture and living standards through superior and inexpensive food, biomedical, water, environmental, materials and military products; and the strengthening of Australian position, through international linkage projects, as a world leader in the development of novel processing technologies.Read moreRead less
Improvements and Optimisation of Water Electrolysis for Hydroxy Gas Production for Metal Cutting Applications. The current technique for metal cutting mainly uses oxygen-acetylene flames, which means for the large number of Australian remote communities oxygen and acetylene bottles have to be transported from major cities. This incurs significant transport costs and associated environmental emissions and presents major safety concerns. Hydroxy flames using electrolysis of water can alleviate the ....Improvements and Optimisation of Water Electrolysis for Hydroxy Gas Production for Metal Cutting Applications. The current technique for metal cutting mainly uses oxygen-acetylene flames, which means for the large number of Australian remote communities oxygen and acetylene bottles have to be transported from major cities. This incurs significant transport costs and associated environmental emissions and presents major safety concerns. Hydroxy flames using electrolysis of water can alleviate these problems and, by utilising renewable electricity, the new technology to be developed in this research will transform tens of thousands of Australian metal workshops to be more environmentally friendly, safer and more cost-effective, thus contributing to the development of an environmentally sustainable Australia. Read moreRead less