Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Development of class-leading bioluminescence resonance energy transfer technologies for real-time monitoring of molecular interactions. The purpose of this project is to develop improved technologies for identifying and developing pharmaceuticals with fewer side effects. The expected outcome is the development of technologies that provide a level of sensitivity and data quality that enables adoption by the biotechnology and pharmaceutical industries.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561042
Funder
Australian Research Council
Funding Amount
$852,705.00
Summary
Establishing a high-throughput Protein Production Unit. We seek to establish a world class high-throughput (H-T) protein production unit, the first of its kind in Australia. Throughout the unit robotic technology will be used to build and test protein expression systems as well as drive large scale protein production. The product of the unit will be high quality, pure protein, effective expression systems and world class research. The unit will act as a centre for research into H-T protein ex ....Establishing a high-throughput Protein Production Unit. We seek to establish a world class high-throughput (H-T) protein production unit, the first of its kind in Australia. Throughout the unit robotic technology will be used to build and test protein expression systems as well as drive large scale protein production. The product of the unit will be high quality, pure protein, effective expression systems and world class research. The unit will act as a centre for research into H-T protein expression technology, will underpin the finest biological research, provide the basis for large "structural genomic" type approaches to biological problems and provide a wealth of projects for the Australian synchrotron.Read moreRead less
ARC/NHMRC Research Network Fluorescence Applications in Biotechnology and Life Sciences. This Network will concentrate Australian research in new applications of fluorescence to biological systems to solve significant problems in health diagnostics, biotechnology and the environment. The scientific goals identified by the Network such as highly selective fluorescent labelling and purpose-engineered fluorochromes will be accompanied by the development of specialised instrumentation. These resear ....ARC/NHMRC Research Network Fluorescence Applications in Biotechnology and Life Sciences. This Network will concentrate Australian research in new applications of fluorescence to biological systems to solve significant problems in health diagnostics, biotechnology and the environment. The scientific goals identified by the Network such as highly selective fluorescent labelling and purpose-engineered fluorochromes will be accompanied by the development of specialised instrumentation. These research directions pursued by strong multi-disciplinary teams spanning biology, chemistry, physics, bioengineering and medicine will benefit from the support of the Network programs. Through its focus on academic - industry collaboration the Network will also facilitate development of basic scientific discoveries into commercial outcomes.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775673
Funder
Australian Research Council
Funding Amount
$1,200,000.00
Summary
A high throughput protein crystallization & imaging facility. Protein crystallography is an important field of research that enables us to understand the precise shape of proteins. The precise shape of a protein determines the function of a protein. This information is essential in understanding the physiological role of a protein and may be used for the development of therapeutics, where approrpiate. We aim to develop a high-throughput robotics system that will enable us to determine the sh ....A high throughput protein crystallization & imaging facility. Protein crystallography is an important field of research that enables us to understand the precise shape of proteins. The precise shape of a protein determines the function of a protein. This information is essential in understanding the physiological role of a protein and may be used for the development of therapeutics, where approrpiate. We aim to develop a high-throughput robotics system that will enable us to determine the shape of many proteins more rapidly, thereby greatly accelerating the pace of biomedical research.Read moreRead less
Engineering safer pastures for livestock. This project aims to develop subterranean clover with elevated condensed tannins in leaves. This important pasture legume is currently a bloat risk for cattle and sheep due to low condensed tannins and high soluble proteins. Bloat is a health issue that costs the Australian and New Zealand livestock industries over $200 million per annum. Condensed tannins can reduce bloat, decrease methane production and improve efficiency of production. A novel approac ....Engineering safer pastures for livestock. This project aims to develop subterranean clover with elevated condensed tannins in leaves. This important pasture legume is currently a bloat risk for cattle and sheep due to low condensed tannins and high soluble proteins. Bloat is a health issue that costs the Australian and New Zealand livestock industries over $200 million per annum. Condensed tannins can reduce bloat, decrease methane production and improve efficiency of production. A novel approach using CRISPR and other innovative molecular techniques will generate breeding lines high in condensed tannins and deliver knowledge applicable to other pasture legumes. Expected outcomes for livestock producers include improved animal welfare, reduced carbon emissions and enhanced profits.Read moreRead less
Bio-recovery of rare earth elements from Australian soils and mine tailings. This project aims to discover how microbes dissolve weathering-resistant phosphate minerals that contain valuable rare earth elements used widely in modern technology. This discovery would create new knowledge in the interdisciplinary fields of biogeochemistry and biohydrometallurgy, using an innovative combination of techniques in metagenomics, microbiology and mineralogy. Expected research outcomes include new, more ....Bio-recovery of rare earth elements from Australian soils and mine tailings. This project aims to discover how microbes dissolve weathering-resistant phosphate minerals that contain valuable rare earth elements used widely in modern technology. This discovery would create new knowledge in the interdisciplinary fields of biogeochemistry and biohydrometallurgy, using an innovative combination of techniques in metagenomics, microbiology and mineralogy. Expected research outcomes include new, more economic and environmentally sustainable biotechnologies for recovering rare earth elements and increasing phosphorus availability in Australian mineral deposits and soils. These outcomes should benefit the mining and agricultural sectors, by decreasing Australia's dependency on overseas REE supply and the use of fertilizers.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100026
Funder
Australian Research Council
Funding Amount
$4,969,663.00
Summary
ARC Training Centre for Cell and Tissue Engineering Technologies. The ARC Training Centre for Cell and Tissue Engineering Technologies aims to provide training to create a highly skilled workforce for the tissue engineering and regenerative medicine sector and to enhance research performance and innovation in Australia through fundamental and applied research carried out in industry-led PhD projects. The research aims to address major aspects of the manufacturing and commercialisation pathway an ....ARC Training Centre for Cell and Tissue Engineering Technologies. The ARC Training Centre for Cell and Tissue Engineering Technologies aims to provide training to create a highly skilled workforce for the tissue engineering and regenerative medicine sector and to enhance research performance and innovation in Australia through fundamental and applied research carried out in industry-led PhD projects. The research aims to address major aspects of the manufacturing and commercialisation pathway and barriers faced by the sector, namely improving process efficiencies, enabling early-stage scale-up (cell/tissue) and development of the sector's supply chain. The knowledge created and research undertaken would help to accelerate commercialisation in regenerative medicine, tissue engineering and cell therapies.Read moreRead less