Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0238397
Funder
Australian Research Council
Funding Amount
$550,000.00
Summary
A ROBOTIC NMR SPECTROMETER FOR ACCELERATED DRUG DISCOVERY. The aim is to establish a facility that will use a robotic NMR instrument to help in the characterisation of drug-protein interactions and in the discovery of new drugs or agrichemicals. The significance is that with the wealth of new information arising on protein sequences from genomics programs there is an urgent need to accelerate the rate of discovery of ligands that bind to these proteins. Such ligands may provide useful drug lea ....A ROBOTIC NMR SPECTROMETER FOR ACCELERATED DRUG DISCOVERY. The aim is to establish a facility that will use a robotic NMR instrument to help in the characterisation of drug-protein interactions and in the discovery of new drugs or agrichemicals. The significance is that with the wealth of new information arising on protein sequences from genomics programs there is an urgent need to accelerate the rate of discovery of ligands that bind to these proteins. Such ligands may provide useful drug leads or help in defining the function of newly discovered proteins. The outcomes will be new knowledge on protein structure and function, and potentially, new bio-active molecules.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453671
Funder
Australian Research Council
Funding Amount
$133,770.00
Summary
NMR Facility for Natural Products Research. The aim is to establish a facility that will use high-field NMR and LC-NMR equipment to help in the characterisation of unknown compounds from natural products and in the discovery of new drugs and agrichemicals. The significance is that the facility will accelerate the rate of discovery of new bioactive molecules and will provide a wealth of new information on plant biodiversity. The outcomes will be new knowledge in natural products chemistry, and po ....NMR Facility for Natural Products Research. The aim is to establish a facility that will use high-field NMR and LC-NMR equipment to help in the characterisation of unknown compounds from natural products and in the discovery of new drugs and agrichemicals. The significance is that the facility will accelerate the rate of discovery of new bioactive molecules and will provide a wealth of new information on plant biodiversity. The outcomes will be new knowledge in natural products chemistry, and potentially, new bioactive molecules.Read moreRead less
Surface Modification of Spray-Dried Powders By Surface-Active Proteins. Internal wall deposits in spray dryers lead to product degradation and pose fire hazards. This situation has limited the manufacturing of high value bio-food powders by the Australian bio-food and dairy industry, which exports 13% of the milk powder in the world. The specific economic benefits to Australia from this project arise from innovative surface modification of powder particles by proteins, development of scientific ....Surface Modification of Spray-Dried Powders By Surface-Active Proteins. Internal wall deposits in spray dryers lead to product degradation and pose fire hazards. This situation has limited the manufacturing of high value bio-food powders by the Australian bio-food and dairy industry, which exports 13% of the milk powder in the world. The specific economic benefits to Australia from this project arise from innovative surface modification of powder particles by proteins, development of scientific instruments and predictive tools based on Computational Fluid Dynamics (CFD). These outcomes will lead to production of free flowing powders from bio-food materials.Read moreRead less
Optical Multiple-Input Multiple-Output Communication Systems. Optical multiple-input multiple-output (MIMO) systems exploit a simple yet powerful principle of diversity to improve the capacity and robustness of optical networks. This proposal focuses on making the most use of two polarisation modes intrinsic to the fiber by applying MIMO techniques to the optical communication systems. This project can potentially create many commercial opportunities in Australia in the area of integrated photon ....Optical Multiple-Input Multiple-Output Communication Systems. Optical multiple-input multiple-output (MIMO) systems exploit a simple yet powerful principle of diversity to improve the capacity and robustness of optical networks. This proposal focuses on making the most use of two polarisation modes intrinsic to the fiber by applying MIMO techniques to the optical communication systems. This project can potentially create many commercial opportunities in Australia in the area of integrated photonic circuits and high-speed digital signal processing. The funding support of these research activities will further enhance Australia's international ICT reputation in this emerging field.Read moreRead less
Development of an integrated methodology to assess dewatering system performance in solid-liquid separation. 3D visualisations of microstructures are possible with techniques such as confocal laser microscopy and high resolution X-ray microtomography. Data obtained in-situ enable direct computation of solids assembly properties and their permeability to fluids. A specific application involving aggregate formation and sediment networks could be evaluated through micro-scale analysis combined with ....Development of an integrated methodology to assess dewatering system performance in solid-liquid separation. 3D visualisations of microstructures are possible with techniques such as confocal laser microscopy and high resolution X-ray microtomography. Data obtained in-situ enable direct computation of solids assembly properties and their permeability to fluids. A specific application involving aggregate formation and sediment networks could be evaluated through micro-scale analysis combined with robust fluid flow simulations. The method can potentially be utilized to predict trends such as filtration behaviour of materials under different states of compression. This offers significant benefits in formulating the design of flocculated systems pertinent to a number of industrial sectors wishing to design optimum solid-liquid separation processes.Read moreRead less
High-Fidelity Modelling for Robotic-Assisted Minimally Invasive Needle Insertion. This project will develop robotic-assisted needle insertion and greatly improve minimally invasive surgery. It will also enhance the establishment of intellectual property for Australian medicine and produce important benefits to the healthcare sector. The proposed symbiotic integration of the systems will advance modelling technologies, and further create new capabilities for a wide range of science and engineerin ....High-Fidelity Modelling for Robotic-Assisted Minimally Invasive Needle Insertion. This project will develop robotic-assisted needle insertion and greatly improve minimally invasive surgery. It will also enhance the establishment of intellectual property for Australian medicine and produce important benefits to the healthcare sector. The proposed symbiotic integration of the systems will advance modelling technologies, and further create new capabilities for a wide range of science and engineering applications. The established methodologies and systems will also provide great potential benefits in many other areas, including microbiology, life sciences and bio/nano-technology. The project's outcomes will further consolidate Australia's position in innovative technologies and international research and development.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775513
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Advanced Process Tomography Research Facility for Multiphase System Studies. The establishment of an advanced process tomography facility at UNSW has several important national benefits, including; increased capacity of the collaborating institutions to train highly qualified personnel to meet new and growing demands in the processing industries; the transfer of research-based cheap and efficient technologies to our industries to enhance their position in a competitive global market; the improve ....Advanced Process Tomography Research Facility for Multiphase System Studies. The establishment of an advanced process tomography facility at UNSW has several important national benefits, including; increased capacity of the collaborating institutions to train highly qualified personnel to meet new and growing demands in the processing industries; the transfer of research-based cheap and efficient technologies to our industries to enhance their position in a competitive global market; the improvement in our culture and living standards through superior and inexpensive food, biomedical, water, environmental, materials and military products; and the strengthening of Australian position, through international linkage projects, as a world leader in the development of novel processing technologies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883073
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
BigNet - A Distributed Wireless Sensor Network Testbed. The infrastructure developed will be of national /international significance, given the rapid emergence of wireless sensor networks. This integrated facility will allow Australia to be a world leading player in the research and technology development as well as the socially responsible deployment of sensor networks. The facility has the explicit aim to ensure that Australia is a technology leader rather than solely a technology user in sens ....BigNet - A Distributed Wireless Sensor Network Testbed. The infrastructure developed will be of national /international significance, given the rapid emergence of wireless sensor networks. This integrated facility will allow Australia to be a world leading player in the research and technology development as well as the socially responsible deployment of sensor networks. The facility has the explicit aim to ensure that Australia is a technology leader rather than solely a technology user in sensor networks. The test facility will mirror practical requirements for WSN implementation in the Great Barrier Reef and in timber plantation, which would offer substantial economic benefits to Australia.Read moreRead less
Compact Low-Cost Tunable UV Lasers for Biosensing Applications. Detection and characterisation of micro-organisms such as airborne biological agents, parasites in domestic water supplies and micro-organisms used in the food and beverage industry, is of national importance. All biological systems have rich absorption signatures in the UV enabling detection of biological specimens with high sensitivity and selectivity using optical methods. For these applications compact and inexpensive tunable U ....Compact Low-Cost Tunable UV Lasers for Biosensing Applications. Detection and characterisation of micro-organisms such as airborne biological agents, parasites in domestic water supplies and micro-organisms used in the food and beverage industry, is of national importance. All biological systems have rich absorption signatures in the UV enabling detection of biological specimens with high sensitivity and selectivity using optical methods. For these applications compact and inexpensive tunable UV lasers are required; however to date tunable UV lasers have been limited to bulky and expensive systems. We propose to engineer novel, low cost, compact, tunable UV cerium lasers and demonstrate their applicability to selective optical detection of micro-organisms.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0228799
Funder
Australian Research Council
Funding Amount
$1,602,000.00
Summary
Australian Membership of the International Gemini Partnership. The International Gemini Partnership is an intergovernmental consortium formed to construct and operate two 8-metre optical/infrared telescopes, one in Chile, and the other in Hawaii. Australia joined the IGP in May 1998, taking approximately 5% of the partnership. The Gemini telescopes have been carefully engineered to exploit the superb atmospheric conditions at both sites, allowing users to address key astronomical problems in way ....Australian Membership of the International Gemini Partnership. The International Gemini Partnership is an intergovernmental consortium formed to construct and operate two 8-metre optical/infrared telescopes, one in Chile, and the other in Hawaii. Australia joined the IGP in May 1998, taking approximately 5% of the partnership. The Gemini telescopes have been carefully engineered to exploit the superb atmospheric conditions at both sites, allowing users to address key astronomical problems in ways not previously possible. Through membership of Gemini, Australian astronomers have access to the world-class facilities necessary to maintain their high international profile and great public visibility in Galactic and extragalactic astronomy, and also to enhance the national capacity to construct advanced scientific instrumentation. Australia has already won a contract to build one of the instruments.Read moreRead less