Adverse effects of sopite syndrome on occupants in wind-excited buildings. Current building motion design guidelines focus primarily on motion perception and complaint rates. However, wind-induced building motion can cause sopite syndrome or early onset motion sickness which adversely affects occupant wellbeing and work performance. This research aims to advance the understanding of the physiology of sopite syndrome, quantify the motion dosage that causes sopite syndrome and determine its advers ....Adverse effects of sopite syndrome on occupants in wind-excited buildings. Current building motion design guidelines focus primarily on motion perception and complaint rates. However, wind-induced building motion can cause sopite syndrome or early onset motion sickness which adversely affects occupant wellbeing and work performance. This research aims to advance the understanding of the physiology of sopite syndrome, quantify the motion dosage that causes sopite syndrome and determine its adverse effects on building occupants in real-world motion environments. This knowledge is expected to guide the formulation of building motion acceptability criteria based on safe motion exposure duration to facilitate the design of tall building that promotes population health and wellbeing and lifts work performance and productivity.Read moreRead less
Generation Of Protective Immunity Against Severe Influenza Disease In Indigenous Australians
Funder
National Health and Medical Research Council
Funding Amount
$1,630,970.00
Summary
Hospitalisation and death rates from influenza are high in the Indigenous population, especially when a new virus emerges. There is an urgent need for a vaccine that protects against all influenza strains. T cells recognising conserved viral regions elicit such protection. As T cells are restricted by proteins called HLAs, which vary across ethnicities, we will define T cell regions for HLAs prominent in Indigenous Australians and define how to generate protective immunity against influenza.
Industrial Transformation Training Centres - Grant ID: IC230100015
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation ....ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation of infrastructure design in Australia and internationally. Achieving carbon neutral infrastructure in its whole life will bring significant far-reaching benefits, including equipping industry with tools required to meet Australia’s emission reduction targets as well as economic, commercial, environmental, and social gains.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100015
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
An Ultra High Resolution Mass Spectrometry Facility for Lipidomics Research. An ultra-high-resolution mass spectrometry facility for lipidomics research:
This proposal aims to establish an ultra-high-resolution, accurate mass spectrometry facility in Australia for comprehensive lipidomics research. The platform would consist of a Thermo Scientific Orbitrap Fusion mass spectrometer interfaced with ultra-high-pressure high-performance liquid chromatography. This proposal will address a major need ....An Ultra High Resolution Mass Spectrometry Facility for Lipidomics Research. An ultra-high-resolution mass spectrometry facility for lipidomics research:
This proposal aims to establish an ultra-high-resolution, accurate mass spectrometry facility in Australia for comprehensive lipidomics research. The platform would consist of a Thermo Scientific Orbitrap Fusion mass spectrometer interfaced with ultra-high-pressure high-performance liquid chromatography. This proposal will address a major need for advanced mass spectrometry-based lipid analysis capabilities across mammalian, plant, parasite, and microalgae research disciplines, as well as enabling fundamental studies of lipid separation, chemistry and reactivity. The instrumentation would be applicable to a diverse range of projects including studies of the role of lipid metabolism in mammalian biochemistry and cell biology, plant biology and parasitology, and micro algae biofuel production.Read moreRead less
Using community engagement and enhanced visual information to promote FireWatch satellite communication as a support for collaborative decision-making. Using continuously updated satellite data, FireWatch will repurpose its professional service for use by the wider public, informing community-based decision-making and action. Communication flows and community decision-making will promote informed action at times of fire stress. Complex visual data will be communicated in clear and compelling way ....Using community engagement and enhanced visual information to promote FireWatch satellite communication as a support for collaborative decision-making. Using continuously updated satellite data, FireWatch will repurpose its professional service for use by the wider public, informing community-based decision-making and action. Communication flows and community decision-making will promote informed action at times of fire stress. Complex visual data will be communicated in clear and compelling ways.Read moreRead less
Estimating the potential supply of environmental services by landholders. Wilderness, natural habitats, biodiversity and other aspects of natural capital and their associated ecosystem services are in decline. Increasing scarcity is driving a surge in interest in these services and their value. It potentially provides opportunities for landholders to be generating income from environmental services provision, and lessens dependency on livestock, crop and fibre production. But how realistic are t ....Estimating the potential supply of environmental services by landholders. Wilderness, natural habitats, biodiversity and other aspects of natural capital and their associated ecosystem services are in decline. Increasing scarcity is driving a surge in interest in these services and their value. It potentially provides opportunities for landholders to be generating income from environmental services provision, and lessens dependency on livestock, crop and fibre production. But how realistic are these prospects? A critical aspect of potential markets for environmental services is their supply. This project examines the supply side of environmental services by exploring determinants of ability and willingness of landholders to provide these services.Read moreRead less
Ecological-epidemiological models of feral swamp buffalo control in northern Australia. This research is locally, nationally and internationally significant because it 1) improves the capacity of the Northern Territory and its traditional aboriginal owners to manage together this prevalent species in an effort to minimise disturbance to native flora and fauna and to understand the long-term implications of continued proliferation, 2) provides a nationally relevant system to monitor and project t ....Ecological-epidemiological models of feral swamp buffalo control in northern Australia. This research is locally, nationally and internationally significant because it 1) improves the capacity of the Northern Territory and its traditional aboriginal owners to manage together this prevalent species in an effort to minimise disturbance to native flora and fauna and to understand the long-term implications of continued proliferation, 2) provides a nationally relevant system to monitor and project the spread of disease through feral animal populations in Australia, and 3) combines quantitative data and robust analytical tools that can be used as a template for solving many broad-scale feral animal problems around the world.Read moreRead less
Mathematical Modelling Of Bacterial Carriage In Children
Funder
National Health and Medical Research Council
Funding Amount
$421,746.00
Summary
Children exposed to larger numbers of other children are at risk of persistent bacterial infections. Such circumstances explain the high rates of ear and chest infections, and skin sores seen in children in historical times. Changing social circumstances (smaller families, better housing, nutrition and hygiene), as well as the introduction of antibiotics, explain the decline of such infections in affluent communities since the early 20th century. However, even today, in affluent countries, child ....Children exposed to larger numbers of other children are at risk of persistent bacterial infections. Such circumstances explain the high rates of ear and chest infections, and skin sores seen in children in historical times. Changing social circumstances (smaller families, better housing, nutrition and hygiene), as well as the introduction of antibiotics, explain the decline of such infections in affluent communities since the early 20th century. However, even today, in affluent countries, children attending group child care are at high risk of ear infections. As many bacteria are resistant, antibiotics are now much less effective than when they were first introduced. Furthermore, there is a continuing load of infection for children in Aboriginal communities, in PNG and other developing countries, causing hearing loss, chronic respiratory problems, and heart disease and renal disease in later life. Using data previously collected from other studies in Indigenous communities and children in child care, mathematical models allow us to ask what if?, and answer important public health questions: 1. What environmental and public health measures can reduce the cycle of cross-infection in child-care and high-risk populations? 2. What coverage rates with pneumococcal vaccine will eliminate the vaccine-specific bacteria from child care centres, from the wider community, and from high risk populations? 3. Will infections with bacteria not covered by vaccine then increase? 4. Will the resistant bacteria tend to disappear if antibiotic use is restricted? 5. Under what circumstances will antibiotics help to control infection? The modelling will promote understanding of the social and health costs of bacterial infection in Aboriginal communities and child care and use educational scenarios to promote uptake of the most cost-effective and socially acceptable interventions.Read moreRead less
Co-designing a resilient water-energy toolbox with Indigenous communities. The aim is to collaboratively create a toolbox of innovative, community-based approaches for water and energy management in remote Australia. This project will combine digital and cultural approaches to create a novel set of tested and evaluated tools for engaging both community and service providers in transforming water and energy use practises in remote Indigenous communities. The key output will be an empirically-test ....Co-designing a resilient water-energy toolbox with Indigenous communities. The aim is to collaboratively create a toolbox of innovative, community-based approaches for water and energy management in remote Australia. This project will combine digital and cultural approaches to create a novel set of tested and evaluated tools for engaging both community and service providers in transforming water and energy use practises in remote Indigenous communities. The key output will be an empirically-tested and user friendly water-energy toolbox tailored to reduce the currently extreme cost of supplying essential services to remote communities. Application of these outputs will significantly reduce demand on local water sources and diesel-generated energy use while creating a skill base for local employment opportunities.Read moreRead less
Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.