Life Cycle Measures of Cost Effectiveness for 4 D CAD in Design and Construct Projects across Industry Sectors. The effective and efficient delivery of complex construction projects will be transformed by the increased application of virtual design and construction technologies, including 4D CAD. By combining a 3D computer model of a design with the time dimension of the construction schedule, 4D CAD enables risks and opportunities to be better managed during the design phase and hence avoid co ....Life Cycle Measures of Cost Effectiveness for 4 D CAD in Design and Construct Projects across Industry Sectors. The effective and efficient delivery of complex construction projects will be transformed by the increased application of virtual design and construction technologies, including 4D CAD. By combining a 3D computer model of a design with the time dimension of the construction schedule, 4D CAD enables risks and opportunities to be better managed during the design phase and hence avoid costly issues during construction. However this requires addition design costs which currently represent a barrier to the uptake of this transforming technology. This project will overcome this by developing a flexible framework that allows the benefits gained across the life cycle of a project through using 4D CAD to be set against the additional costs and thus make this emerging technology more attractive to industry. Significantly this research will be based on comparative cases studies across different industry sectors including civil, building, and process engineering.Read moreRead less
Development of a novel technology for DSP separation and soda recovery in alumina refineries. The successful completion of this project will provide economic and environmental benefits to the Australian alumina industry. For example, this project will provide an effective and economical method for separation of DSP (desilication product) from red mud (thus reducing the pollution by the long-term alkalinity) as well as a new solution to soda recovery. The technology developed will be able to be u ....Development of a novel technology for DSP separation and soda recovery in alumina refineries. The successful completion of this project will provide economic and environmental benefits to the Australian alumina industry. For example, this project will provide an effective and economical method for separation of DSP (desilication product) from red mud (thus reducing the pollution by the long-term alkalinity) as well as a new solution to soda recovery. The technology developed will be able to be used as an example to the waste management and recovery of other Australian mineral, energy and chemical industries. The modelling and mechanism studies will also contribute to materials separation and processing.Read moreRead less
Adaptation of Water Sensitive Urban Design (WSUD) to Climate Change, Changing Transport Patterns and Urban Form. This research will (a) provide guidance on future adaptations of stormwater quality infrastructure, (b) provide better scientific understanding of pollutant movements in urban systems and (c) provide methodology to 'future proof' infrastructure design against the pressures of climate change and urban population growth. Project outputs will (a) enable water-sensitive urban designs to b ....Adaptation of Water Sensitive Urban Design (WSUD) to Climate Change, Changing Transport Patterns and Urban Form. This research will (a) provide guidance on future adaptations of stormwater quality infrastructure, (b) provide better scientific understanding of pollutant movements in urban systems and (c) provide methodology to 'future proof' infrastructure design against the pressures of climate change and urban population growth. Project outputs will (a) enable water-sensitive urban designs to be applied reliably and (b) minimise the cost of re-building assets before the end of their design life due to climate change. The ultimate benefit is the reduction in water pollution from roadways leading to improved human and ecosystem well-being of urban communities.Read moreRead less
The design and construction of quality, sustainable and affordable pre-made housing in Australia - optimisation and integration. Historically, industrialised construction has resulted in an industrialisation of the parts, rather than an industrialisation of the ensemble. In contrast, this project will integrate architecture and engineering, as well as construction and development to optimise the ensemble, and deliver architectural quality in industrially produced affordable housing.
Development of a Novel Flue Gas Desulphurization Technology for Alumina Refineries. This project aims to develop a novel technology of flue gas desulphurization for alumina industry. The successful completion of this project will provide a practical solution to the SOx emission problem in alumina refineries. Specifically, we aim to make use of the waste causticiser sludge discharged during the causticisation of the liquor streams and the used filter aid after the polishing filtration of the ref ....Development of a Novel Flue Gas Desulphurization Technology for Alumina Refineries. This project aims to develop a novel technology of flue gas desulphurization for alumina industry. The successful completion of this project will provide a practical solution to the SOx emission problem in alumina refineries. Specifically, we aim to make use of the waste causticiser sludge discharged during the causticisation of the liquor streams and the used filter aid after the polishing filtration of the refinery pregnant liquors as reagent to remove SOx emitted by the power house and the alumina calciners. We also aim to recover some alumina during the process of flue gas desulphurization thus further reducing the cost of air pollution control.Read moreRead less
Design guidelines for safety-critical controllers in high-risk environments. This project aims to generate novel product design guidelines for developing safer controllers for use by potentially stressed individuals in high-risk situations. It will do this by generating specific insights and verifying generalisable solutions from the context of total artificial heart recipients –who must engage with critical controllers constantly. This project expects to generate new knowledge in design by esta ....Design guidelines for safety-critical controllers in high-risk environments. This project aims to generate novel product design guidelines for developing safer controllers for use by potentially stressed individuals in high-risk situations. It will do this by generating specific insights and verifying generalisable solutions from the context of total artificial heart recipients –who must engage with critical controllers constantly. This project expects to generate new knowledge in design by establishing a new research topic around an under-examined user cohort. Expected outcomes of this project include interaction design theory developments and improved controller design techniques. This should provide significant benefits and competitive advantages by lowering stress and improving safety across a range of contexts.Read moreRead less
Applying the CCK framework to angiogenic-based therapeutics. The aim of this project is to graft peptides involved in angiogenesis-related disorders onto a mini-protein framework. The cyclic cystine knot (CCK) framework is a plant based protein framework that has unique structural properties that make it exceptionally stable. The significance of this project is that the framework has the potential to overcome the limitations that are generally associated with peptide-based therapeutics, includin ....Applying the CCK framework to angiogenic-based therapeutics. The aim of this project is to graft peptides involved in angiogenesis-related disorders onto a mini-protein framework. The cyclic cystine knot (CCK) framework is a plant based protein framework that has unique structural properties that make it exceptionally stable. The significance of this project is that the framework has the potential to overcome the limitations that are generally associated with peptide-based therapeutics, including poor stability and bioavailability. Vastly improved therapeutic leads may be produced from this approach.Read moreRead less
What is in therapeutically prescribed herbal medicines? Phytochemical characterisation of steroidal saponins from two popular nutraceuticals, False Unicorn and Tribulus terrestris. Plants containing steroidal saponins have long been used as therapeutic products, but their active constituents remain poorly characterized. This project aims to identify and structurally characterize steroidal saponins from False Unicorn and Tribulus terrestris, two popular nutraceuticals which are currently marketed ....What is in therapeutically prescribed herbal medicines? Phytochemical characterisation of steroidal saponins from two popular nutraceuticals, False Unicorn and Tribulus terrestris. Plants containing steroidal saponins have long been used as therapeutic products, but their active constituents remain poorly characterized. This project aims to identify and structurally characterize steroidal saponins from False Unicorn and Tribulus terrestris, two popular nutraceuticals which are currently marketed in Australia. Existing knowledge of these saponin constituents is surprisingly incomplete and inaccurate. Full structural elucidation will enable the development of 'standardised' herbal saponin profiles for better control of product quality and will allow alternatives for the herbs to be chosen, which cannot be undertaken until this composition is known. A phytochemical survey of Australian Tribulus terrestris will determine whether this native sub-species is suitable for commercial harvest.Read moreRead less
Discovery and characterisation of novel spider-venom peptides targeting the human sodium ion channel Nav1.7. Drugs that selectively block the human sodium ion channel Nav1.7 are likely to be powerful analgesics for treating a wide variety of pain conditions. However, it has proved difficult to obtain selective blockers of this channel. The aim of this project is to determine whether spider-venoms might provide a source of highly selective Nav1.7 blockers.
Extending building information models (BIM) for specifications and cost planning. The recognition in the 1990's that inefficiencies in the design, construction and maintenance of buildings and infrastructure were costing up to 30 per cent of the total constructed cost of buildings led to a push for the more efficient use of information. The major change in the industry to date has been the introduction of Building Information Models (BIM). Uptake has now reached the tipping point where it is be ....Extending building information models (BIM) for specifications and cost planning. The recognition in the 1990's that inefficiencies in the design, construction and maintenance of buildings and infrastructure were costing up to 30 per cent of the total constructed cost of buildings led to a push for the more efficient use of information. The major change in the industry to date has been the introduction of Building Information Models (BIM). Uptake has now reached the tipping point where it is becoming pervasive. This project examines methods of adding value to existing BIM information which will allow the industry and clients to achieve a higher level of efficiency than can be gained just through substitution of BIM for current processes.Read moreRead less