Engineering approaches towards atomic imaging of bacterial cells. This project aims to develop novel approaches for analysis of single biological cells at atomic scale. The project will first develop an approach by utilising nanoscale ion beam to interact with the frozen cells in a controllable manner, followed by performing nanoscale dissection and analyses. By introducing engineered two-dimensional materials, namely graphene, atomic resolution three-dimensional imaging of the cellular chemistr ....Engineering approaches towards atomic imaging of bacterial cells. This project aims to develop novel approaches for analysis of single biological cells at atomic scale. The project will first develop an approach by utilising nanoscale ion beam to interact with the frozen cells in a controllable manner, followed by performing nanoscale dissection and analyses. By introducing engineered two-dimensional materials, namely graphene, atomic resolution three-dimensional imaging of the cellular chemistry will become feasible, which will shed light on various fundamental mechanisms inside the cells. This will provide significant benefits upon success, and will impact a wide spectrum of fields from understanding cellular functions to developing effective drugs.Read moreRead less
Ultrathin Gold Nanocrystal Conductors for Wearable Epidermal Biofuel Cells. This project aims to fabricate ultrathin, soft yet stretchable gold nanocrystal conductors to push the thickness limit of next-generation soft bioelectrodes for fabrication of wearable epidermal biofuel cells. This will generate new knowledge and patentable technologies related to design/fabrication of soft nanocrystal conductors, bioanode and biocathode, which require to be thin, soft, conductive and biocompatible. Expe ....Ultrathin Gold Nanocrystal Conductors for Wearable Epidermal Biofuel Cells. This project aims to fabricate ultrathin, soft yet stretchable gold nanocrystal conductors to push the thickness limit of next-generation soft bioelectrodes for fabrication of wearable epidermal biofuel cells. This will generate new knowledge and patentable technologies related to design/fabrication of soft nanocrystal conductors, bioanode and biocathode, which require to be thin, soft, conductive and biocompatible. Expected outcomes of this project include enhanced national capacity in disruptive wearable bioelectronics, strengthening international collaborations, unskilled workforce training, as well as advancement of Australian knowledge base in the fields of nanotechnology, materials science, energy, biosensors and bioelectronics.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100985
Funder
Australian Research Council
Funding Amount
$427,116.00
Summary
Shining a Light on Brain Temperature with Near-Infrared Nanosensors. This project aims to develop a contactless thermometry approach based on near-infrared fluorescence to map brain or nerve temperature in real-time. This research expects to generate new knowledge in the field of neuroscience using tools from optics, nanotechnology and materials science. The technique generated as a result of this project is expected to enable the quantification of the transient local heating of the nervous syst ....Shining a Light on Brain Temperature with Near-Infrared Nanosensors. This project aims to develop a contactless thermometry approach based on near-infrared fluorescence to map brain or nerve temperature in real-time. This research expects to generate new knowledge in the field of neuroscience using tools from optics, nanotechnology and materials science. The technique generated as a result of this project is expected to enable the quantification of the transient local heating of the nervous system in different situations and the study of how this affects neural function. This is expected to provide significant benefits, enabling the development of regulatory frameworks that ensure the safe implementation of new therapies for neurological and neurodegenerative disorders.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100839
Funder
Australian Research Council
Funding Amount
$442,162.00
Summary
Nanoarchitectured platform technology for molecular profiling of exosomes. The aim of this project is to develop a set of cutting-edge nanotechnologies and a nanofabrication strategy to create a highly sensitive platform technology for exosome and exosomal miRNA analysis. This project aims to generate new knowledge in mesoporus nanomaterials and transudcer as well as exosome chemistry by developing nanostructure-based platform technology (device) for automated and rapid analysis. This project's ....Nanoarchitectured platform technology for molecular profiling of exosomes. The aim of this project is to develop a set of cutting-edge nanotechnologies and a nanofabrication strategy to create a highly sensitive platform technology for exosome and exosomal miRNA analysis. This project aims to generate new knowledge in mesoporus nanomaterials and transudcer as well as exosome chemistry by developing nanostructure-based platform technology (device) for automated and rapid analysis. This project's findings are expected to provide Australia with cutting-edge expertise for developing a next-generation platform technology for analysing exosomes and other relevant biomolecules, with the potential to deliver valuable intellectual property of commercial interest and economic benefit through technological advancements.Read moreRead less
Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this ....Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate. Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this project include a new fundamental understanding of the effect of mechanical properties on cell function, novel insights into the regulation of stem cell fate, and the development of a new class of roughness-tunable materials suitable for use in tissue engineering and pharmaceutical applications. Read moreRead less
Exploring the bio-nano interface in plants to enhance crop growth. This project aims to improve the delivery of nutrients and therapeutics to plants by understanding their interactions with nanomaterials. This will create new knowledge on the impact of air, water, and soilborne nanomaterials utilizing cutting-edge bio-nano characterization techniques, innovative lab testing, and high-throughput nanoparticle coating and screening. Expected outcomes of the project include 1) an understanding into ....Exploring the bio-nano interface in plants to enhance crop growth. This project aims to improve the delivery of nutrients and therapeutics to plants by understanding their interactions with nanomaterials. This will create new knowledge on the impact of air, water, and soilborne nanomaterials utilizing cutting-edge bio-nano characterization techniques, innovative lab testing, and high-throughput nanoparticle coating and screening. Expected outcomes of the project include 1) an understanding into how nanomaterial coating technologies impact nanomaterial properties, which will 2) shed light on how nanomaterials interact with plants, which leads to 3) breakthroughs in using nanomaterials to deliver nutrients, fertilizers, and pesticides to boost crop yields and productivity in Australian agriculture.Read moreRead less
ARC Centre of Excellence for Transformative Meta-Optical Systems. The ARC Centre of Excellence for Transformative Meta-Optical Systems will develop the next-generation of miniaturised optical systems with functionalities beyond what is conceivable today. By harnessing the disruptive concept of meta-optics, the Centre will overcome complex challenges in light generation, manipulation and detection at the nanoscale. The Centre brings together a trans-disciplinary team of world-leaders in science, ....ARC Centre of Excellence for Transformative Meta-Optical Systems. The ARC Centre of Excellence for Transformative Meta-Optical Systems will develop the next-generation of miniaturised optical systems with functionalities beyond what is conceivable today. By harnessing the disruptive concept of meta-optics, the Centre will overcome complex challenges in light generation, manipulation and detection at the nanoscale. The Centre brings together a trans-disciplinary team of world-leaders in science, technology and engineering to deliver scientific innovations in optical systems for the Fourth Industrial Revolution. The research outcomes will underpin future technologies, including real-time holographic displays, artificial vision for autonomous systems to see the invisible, and ultra-fast light-based WiFi.Read moreRead less
Nanobionic plants. This project aims to develop nanobionic plants as network of semi-permanent sensors capable of rapid, sensitive, selective and unmanned detection and detoxification of chemical warfare agents in aquatic environments and in open air on-site, to allow timely and effective countermeasures. The anticipated goal is to advance the field of advanced manufacturing, environmental change, and nanotechnology with potential to support new national defence capabilities and to value-add Aus ....Nanobionic plants. This project aims to develop nanobionic plants as network of semi-permanent sensors capable of rapid, sensitive, selective and unmanned detection and detoxification of chemical warfare agents in aquatic environments and in open air on-site, to allow timely and effective countermeasures. The anticipated goal is to advance the field of advanced manufacturing, environmental change, and nanotechnology with potential to support new national defence capabilities and to value-add Australian manufacturing industries with innovative, disruptive technologies that lead to achievable opportunities to address its unique needs and to claim Australia’s position within the competitive global manufacturing and defence technology market.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100071
Funder
Australian Research Council
Funding Amount
$535,000.00
Summary
Photonic Chip Integration Facility. This project will create a Photonic Chip Integration Facility responding to newly emerging global trends towards low loss waveguides and wider coverage of the optical spectrum.
The tool will grow ultrahigh quality silicon nitride and oxide thin films in a manner that is compatible with electronics and other delicate materials, balancing flexibility for materials exploration with reliability and repeatability required for photonic chip systems research. The pr ....Photonic Chip Integration Facility. This project will create a Photonic Chip Integration Facility responding to newly emerging global trends towards low loss waveguides and wider coverage of the optical spectrum.
The tool will grow ultrahigh quality silicon nitride and oxide thin films in a manner that is compatible with electronics and other delicate materials, balancing flexibility for materials exploration with reliability and repeatability required for photonic chip systems research. The proposed facility will support Australian researchers from diverse disciplines spanning broadband networks, sensing, quantum technology, materials science, and beyond while providing a clear path for translating discoveries out of the lab towards scale up industrial manufacture
Read moreRead less