The virtual human knee. This project aims to investigate the Virtual Human Knee (VHK) which provides a baseline knowledge about knee mechanics in healthy individuals and a tool for studying knee mechanics in silico. The new knowledge can be used for identifying individuals most at risk for injury, developing solutions for preventing injury and for assessing knee reconstruction and implantation methods. As such, VHK will mitigate the burden of knee injury to Australia and worldwide by progressing ....The virtual human knee. This project aims to investigate the Virtual Human Knee (VHK) which provides a baseline knowledge about knee mechanics in healthy individuals and a tool for studying knee mechanics in silico. The new knowledge can be used for identifying individuals most at risk for injury, developing solutions for preventing injury and for assessing knee reconstruction and implantation methods. As such, VHK will mitigate the burden of knee injury to Australia and worldwide by progressing disciplines including anatomy, bio-mechanics, sport science, rehabilitation, surgery and medical devices.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100078
Funder
Australian Research Council
Funding Amount
$190,000.00
Summary
An advanced multimodal terahertz spectroscopy and imaging system for WA. An advanced multimodal terahertz spectroscopy and imaging system: Terahertz (THz) technology is in use in diverse applications from semiconductor inspection, metamaterials, biology and protein analysis, pharmaceutical sciences and formulations; security and surveillance, and biomedical imaging for burn assessment and cancer detection. This project will provide researchers with access to state-of-the-art THz spectroscopy and ....An advanced multimodal terahertz spectroscopy and imaging system for WA. An advanced multimodal terahertz spectroscopy and imaging system: Terahertz (THz) technology is in use in diverse applications from semiconductor inspection, metamaterials, biology and protein analysis, pharmaceutical sciences and formulations; security and surveillance, and biomedical imaging for burn assessment and cancer detection. This project will provide researchers with access to state-of-the-art THz spectroscopy and imaging facilities, resulting in high-impact outcomes across the physical and biological sciences and engineering, broadly contributing to Australia's economic and social well being.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100057
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
A high-resolution X-ray microtomography system. This project aims to establish a Scanco microCT 50 high resolution X-Ray microtomography system, to non-destructively visualise and quantitatively characterise complex samples, including advanced composites, tissue engineering constructs, biological tissues, minerals and fossils. The non-destructive characterisation of these samples is critical to advance research. The versatile system offers high spatial resolution (down to 500 nm voxel size) and ....A high-resolution X-ray microtomography system. This project aims to establish a Scanco microCT 50 high resolution X-Ray microtomography system, to non-destructively visualise and quantitatively characterise complex samples, including advanced composites, tissue engineering constructs, biological tissues, minerals and fossils. The non-destructive characterisation of these samples is critical to advance research. The versatile system offers high spatial resolution (down to 500 nm voxel size) and large sample size (up to 100 mm diameter). The project will enable progress in advanced composites, additive bio-manufacturing, physiology of biological tissues and palaeontology which will benefit Australian science. Additionally, through commercialisation and the formation of new companies, the project could potentially result in economic and health benefits to the wider Australian population and economy.Read moreRead less
Special Research Initiatives - Grant ID: SR0354734
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving h ....The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving health care and reducing health care costs. To be successful, a device must include all relevant disciplines in the research, development and testing phases. This network will bring together these groups, promoting knowledge sharing and cross-disciplinary investigations that illuminate current device limitations and potential solutions.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise ....Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise therapies and diagnostic techniques for promoting hip strength. The project will contribute to the engineering of biological tissue and the development of high-strength and light-weight bio-inspired materials.Read moreRead less
Properties of nanomaterials determine their disposal by liver cells. This project aims to understand how the liver handles and is affected by nanomaterials in the body. Nanomaterials are widely used in industrial, environmental, consumer and drug products, but how they affect human health is poorly understood. This project will characterise the spatiotemporal distribution of a set of nanomaterials with defined attributes in naïve and modified livers using chemistry, imaging and biological method ....Properties of nanomaterials determine their disposal by liver cells. This project aims to understand how the liver handles and is affected by nanomaterials in the body. Nanomaterials are widely used in industrial, environmental, consumer and drug products, but how they affect human health is poorly understood. This project will characterise the spatiotemporal distribution of a set of nanomaterials with defined attributes in naïve and modified livers using chemistry, imaging and biological methods. This work is expected to determine how nanomaterials’ attributes direct pathways for liver cell disposal and describe nanomaterial–liver interactions at the cellular level, information crucial in enabling safer nanomaterials for use in products such as drug formulations, sunscreens and cosmetics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100020
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
High bandwidth, high speed, terahertz optical sampling and analysis system. This project aims to promote scientific and technological research by providing access to a wide bandwidth, high speed, high resolution advanced terahertz spectrometer. Terahertz frequencies are the least-explored region of the electromagnetic spectrum and investment here is likely to yield scientific and technological reward. Expected outcomes are new commercial devices and products operating in the terahertz regime. Th ....High bandwidth, high speed, terahertz optical sampling and analysis system. This project aims to promote scientific and technological research by providing access to a wide bandwidth, high speed, high resolution advanced terahertz spectrometer. Terahertz frequencies are the least-explored region of the electromagnetic spectrum and investment here is likely to yield scientific and technological reward. Expected outcomes are new commercial devices and products operating in the terahertz regime. The project’s expected effects include new commercial terahertz products; better monitoring of explosives and toxins; research training and job creation; reduced risk in decision making, especially when monitoring water; and cultural benefits, through applying terahertz methods to artworks.Read moreRead less
Deep reinforcement learning for discovering and visualising biomarkers. This project aims to develop novel methods for discovering and visualising optimal bio-markers from chest computed tomography images based on extensions of recently developed deep reinforcement learning techniques. The extensions proposed in this project will advance medical image analysis by allowing an efficient analysis of large dimensionality inputs in their original high resolution. In addition, this project will be the ....Deep reinforcement learning for discovering and visualising biomarkers. This project aims to develop novel methods for discovering and visualising optimal bio-markers from chest computed tomography images based on extensions of recently developed deep reinforcement learning techniques. The extensions proposed in this project will advance medical image analysis by allowing an efficient analysis of large dimensionality inputs in their original high resolution. In addition, this project will be the first approach capable of discovering previously unknown biomarkers associated with important clinical outcomes. The project will validate the approach on a real-world case study data set concerning the prediction of five-year survival of chronic disease.Read moreRead less
Multi-modal virtual microscopy for quantitative diagnostic pathology. This project will contribute to the next generation of virtual microscopy systems that provide innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of diagnostic pathology. These tools will especially contribute to the screening and diagnosis of cervical, lung and bladder cancer.