How do mechanics, neural drive and muscle architecture interact in muscles? This project will determine how an individual person’s muscle activity, muscle structure and mechanical properties, and the local mechanical conditions around the muscle interact as muscles move and deform, by using experiments and personalised computational models that can examine these factors and their interactions concurrently. To achieve this, we will develop novel magnetic resonance imaging methods to measure the m ....How do mechanics, neural drive and muscle architecture interact in muscles? This project will determine how an individual person’s muscle activity, muscle structure and mechanical properties, and the local mechanical conditions around the muscle interact as muscles move and deform, by using experiments and personalised computational models that can examine these factors and their interactions concurrently. To achieve this, we will develop novel magnetic resonance imaging methods to measure the mechanical properties of muscles in humans and methods for modelling muscles. As well as answering fundamental scientific questions about muscle function, these new techniques will provide a platform for studying other muscles, and for future development of muscle training methods and technologies to optimise muscle function.Read moreRead less
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100020
Funder
Australian Research Council
Funding Amount
$3,998,796.00
Summary
ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simula ....ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simulation system and robot simulators for surgical training and medical device assessment, and post-surgical assessment tools. The outcomes of the centre will significantly contribute to Australia by improved health outcomes, economic benefits, and a skilled workforce able to advance this joint biomechanics fields.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Erosion processes in soils across scales. This project aims to develop a monitoring tool for predicting the evolution of internal erosion in dams based on innovative electromagnetic observation methods. Internal erosion is an insidious process occurring in the obscurity of the soil’s pore system until its consequences become visible and threaten the stability of the dams. These water retaining structures are vital for the future water and energy supply for our society and their failure can be ca ....Erosion processes in soils across scales. This project aims to develop a monitoring tool for predicting the evolution of internal erosion in dams based on innovative electromagnetic observation methods. Internal erosion is an insidious process occurring in the obscurity of the soil’s pore system until its consequences become visible and threaten the stability of the dams. These water retaining structures are vital for the future water and energy supply for our society and their failure can be catastrophic. By establishing an improved understanding of internal erosion as a sequence of processes on various scales, from the onset of erosion until the failure of the structure, this project will place Australia at the forefront of dam safety assessment.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100817
Funder
Australian Research Council
Funding Amount
$458,460.00
Summary
Predicting internal erosion in dams using real-time coupled experiments. Internal erosion causes nearly half of embankment dam failures globally. This project aims to develop a mechanics-based understanding of internal erosion to overcome the limitations of existing empirical approaches that do not capture the underlying physics. By innovatively coupling computational and physical experiments in real-time, this project expects to generate new insights that identify the factors leading to the ini ....Predicting internal erosion in dams using real-time coupled experiments. Internal erosion causes nearly half of embankment dam failures globally. This project aims to develop a mechanics-based understanding of internal erosion to overcome the limitations of existing empirical approaches that do not capture the underlying physics. By innovatively coupling computational and physical experiments in real-time, this project expects to generate new insights that identify the factors leading to the initiation and continuation of internal erosion. The expected outcome of this project is a probabilistic framework able to predict the internal erosion process. This should significantly enhance and inform the design of erosion control measures and provide a holistic risk assessment for embankment dams.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100015
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation ....ARC Training Centre for Whole Life Design of Carbon Neutral Infrastructure. This Centre aims to transform the capability of civil infrastructure stakeholders to design, construct, operate and dispose of infrastructure in a carbon neutral way. By training industry-embedded PhDs and postdocs in the methodology and technology required to design out excess carbon of infrastructure in its whole life, this Centre expects to lead the world in sustainable infrastructure design, enabling a new generation of infrastructure design in Australia and internationally. Achieving carbon neutral infrastructure in its whole life will bring significant far-reaching benefits, including equipping industry with tools required to meet Australia’s emission reduction targets as well as economic, commercial, environmental, and social gains.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100006
Funder
Australian Research Council
Funding Amount
$3,937,625.00
Summary
ARC Training Centre for Advanced Technologies in Rail Track Infrastructure. The ARC Training Centre for Advanced Technologies in Rail Track Infrastructure aims to transform Australia’s rail construction and maintenance technologies through specialist training of industry-focused researchers. Generation of new knowledge and close collaboration with companies within the rail supply chain will result in enhanced rail capacity and supply chain efficiency across the rail network. This will include in ....ARC Training Centre for Advanced Technologies in Rail Track Infrastructure. The ARC Training Centre for Advanced Technologies in Rail Track Infrastructure aims to transform Australia’s rail construction and maintenance technologies through specialist training of industry-focused researchers. Generation of new knowledge and close collaboration with companies within the rail supply chain will result in enhanced rail capacity and supply chain efficiency across the rail network. This will include increased axle loads and higher speeds, greater safety margins, reduced construction and maintenance costs, and a body of competent railway professionals in the nation’s work force.Read moreRead less