The virtual human knee. This project aims to investigate the Virtual Human Knee (VHK) which provides a baseline knowledge about knee mechanics in healthy individuals and a tool for studying knee mechanics in silico. The new knowledge can be used for identifying individuals most at risk for injury, developing solutions for preventing injury and for assessing knee reconstruction and implantation methods. As such, VHK will mitigate the burden of knee injury to Australia and worldwide by progressing ....The virtual human knee. This project aims to investigate the Virtual Human Knee (VHK) which provides a baseline knowledge about knee mechanics in healthy individuals and a tool for studying knee mechanics in silico. The new knowledge can be used for identifying individuals most at risk for injury, developing solutions for preventing injury and for assessing knee reconstruction and implantation methods. As such, VHK will mitigate the burden of knee injury to Australia and worldwide by progressing disciplines including anatomy, bio-mechanics, sport science, rehabilitation, surgery and medical devices.Read moreRead less
Elucidating the mechanics of facet dislocation and fracture in the neck. This project aims to address shortcomings in understanding the mechanics of neck trauma. Understanding the mechanical factors leading to cervical facet dislocation and fracture is necessary to improve injury prevention strategies and their assessment. This project expects to generate new knowledge in the area of spinal injury biomechanics, developing and using new experimental techniques. The project expects to provide know ....Elucidating the mechanics of facet dislocation and fracture in the neck. This project aims to address shortcomings in understanding the mechanics of neck trauma. Understanding the mechanical factors leading to cervical facet dislocation and fracture is necessary to improve injury prevention strategies and their assessment. This project expects to generate new knowledge in the area of spinal injury biomechanics, developing and using new experimental techniques. The project expects to provide knowledge necessary to improve crash test dummy design, associated injury criteria, and computational models, which provide the potential for improved injury prevention measures and methods for assessing existing and new technologies. The anticipated benefits of this project will be significant in reducing the personal and economic burden of spinal injuries.Read moreRead less
Prediction of inertial particle focusing in curved microfluidic ducts. This project aims to develop mathematical models to predict migration of particles suspended in flow through curved microfluidic ducts and their focusing by size to different regions in the cross-section of the duct. New knowledge in mathematics and engineering will be generated through models that capture the two-way force balance between fluid and particles and by a novel use of asymptotics for computational efficiency. Exp ....Prediction of inertial particle focusing in curved microfluidic ducts. This project aims to develop mathematical models to predict migration of particles suspended in flow through curved microfluidic ducts and their focusing by size to different regions in the cross-section of the duct. New knowledge in mathematics and engineering will be generated through models that capture the two-way force balance between fluid and particles and by a novel use of asymptotics for computational efficiency. Expected outcomes are understanding of the physics that drives particle migration and the parameters that may be used to control particle focusing. This will benefit design and operation of microfluidic devices for particle sorting as required for "liquid biopsy", the isolation of cancer cells in a routine blood sample.Read moreRead less
Three-dimensional Simulation of Trabecular Bone Remodelling. Nearly 2 million Australians currently suffer from osteoporosis. Statistics indicate that 25% of Australian women and 17% of men will develop an osteoporotic fracture. The cost of osteoporosis is $7.4 billion per annum; the numbers of affected individuals and costs are expected to continue increasing. Clearly, improvements to osteoporosis diagnosis, fracture risk assessment, and effective treatments are still urgently needed. The p ....Three-dimensional Simulation of Trabecular Bone Remodelling. Nearly 2 million Australians currently suffer from osteoporosis. Statistics indicate that 25% of Australian women and 17% of men will develop an osteoporotic fracture. The cost of osteoporosis is $7.4 billion per annum; the numbers of affected individuals and costs are expected to continue increasing. Clearly, improvements to osteoporosis diagnosis, fracture risk assessment, and effective treatments are still urgently needed. The proposed project aims to create a tool for understanding the mechanisms of bone loss and predicting the effects of osteoporosis therapies. It represents a solid contribution to the knowledge base necessary for advancing osteoporosis research and ultimately reducing the incidence of osteoporotic fracture.Read moreRead less
A New Generic Approach for Assessing Blast Effects on Reinforced Concrete Members. A framework allow for both flexural and shear response analysis using a new segmental approach is developed in this proposal. A blast test program is designed to validate the framework for reinforced concrete members. The validated framework is then used to derive normalised pressure impulse programs for reinforced members in unconfined and confined spaces. This project will provide design engineers guidelines for ....A New Generic Approach for Assessing Blast Effects on Reinforced Concrete Members. A framework allow for both flexural and shear response analysis using a new segmental approach is developed in this proposal. A blast test program is designed to validate the framework for reinforced concrete members. The validated framework is then used to derive normalised pressure impulse programs for reinforced members in unconfined and confined spaces. This project will provide design engineers guidelines for reliably and quickly assessing the effect of different kinds of blast loads on different types and properties and geometries of reinforced concrete structural members, saving computation time and efforts while providing increased realism and accuracy.Read moreRead less
Cost Effective Pipeline Condition Assessment Using Paired Pressure Sensor Arrays. Water distribution networks represent society's most important infrastructure asset. They are buried pipes and are often old and deteriorating. Cost-effective methods to assess their physical condition are urgently needed. This research will develop a novel and advanced approach to determine the interior condition of pipes quickly and effectively using small water hammer pulses or waves. Paired pressure sensor arra ....Cost Effective Pipeline Condition Assessment Using Paired Pressure Sensor Arrays. Water distribution networks represent society's most important infrastructure asset. They are buried pipes and are often old and deteriorating. Cost-effective methods to assess their physical condition are urgently needed. This research will develop a novel and advanced approach to determine the interior condition of pipes quickly and effectively using small water hammer pulses or waves. Paired pressure sensor arrays will be used to measure reflections of the waves in pipes and these methods will enable finer resolution and identification of pipeline faults, such as wall thickness loss and leakage while at the same time allowing operational continuity. The outcome will be powerful tools to more cost effectively manage these crucial assets.Read moreRead less
High-resolution pipeline condition assessment using hydraulic transients. This project aims to develop urgently needed non-invasive methods to assess fine detail of a pipe’s condition and allow ‘just in time’ predictive repair. Water distribution networks are society's most important infrastructure asset. They consist of buried pipes that are often old and deteriorating, and annual maintenance overhead exceeds $1 billion per year in Australia alone. The project will develop cost-effective powerf ....High-resolution pipeline condition assessment using hydraulic transients. This project aims to develop urgently needed non-invasive methods to assess fine detail of a pipe’s condition and allow ‘just in time’ predictive repair. Water distribution networks are society's most important infrastructure asset. They consist of buried pipes that are often old and deteriorating, and annual maintenance overhead exceeds $1 billion per year in Australia alone. The project will develop cost-effective powerful tools to identify faults, such as pipe wall corrosion and blockages, while allowing operational continuity. The expected outcome is high-resolution images of wall condition of pipes using high-frequency pressure transients and sophisticated fibre optic sensor arrays.Read moreRead less
Next-generation smart water network for performance-driven asset management. This project aims to develop smart water network systems and techniques for continuous monitoring and early detection of structural failure in water distribution systems. Water assets are critical infrastructure, and they consist of a network of buried pipes that are old and deteriorating, with an annual maintenance overhead exceeding $1billion per year in Australia. This project is expected to deliver next-generation s ....Next-generation smart water network for performance-driven asset management. This project aims to develop smart water network systems and techniques for continuous monitoring and early detection of structural failure in water distribution systems. Water assets are critical infrastructure, and they consist of a network of buried pipes that are old and deteriorating, with an annual maintenance overhead exceeding $1billion per year in Australia. This project is expected to deliver next-generation smart water technology that enables continuous assessment of the actual performance of water pipe networks, guide “just in time” pipe replacement and optimise operations. This technology will assist asset managers to make informed decisions, strategically prioritise investment and extend asset life.Read moreRead less
Smart Pipe Condition Assessment in Water Distribution Systems. The project aims to develop an urgently needed smart pipe fault diagnosis, characterisation and prognosis system. Analysis techniques will be used for the detailed mapping of buried pipe condition between access points using micro-sized transient pressure waves. Water assets are critical infrastructure and they consist of a network of pipes that are often old and deteriorating. The annual maintenance cost exceeds $1b per year in Aus ....Smart Pipe Condition Assessment in Water Distribution Systems. The project aims to develop an urgently needed smart pipe fault diagnosis, characterisation and prognosis system. Analysis techniques will be used for the detailed mapping of buried pipe condition between access points using micro-sized transient pressure waves. Water assets are critical infrastructure and they consist of a network of pipes that are often old and deteriorating. The annual maintenance cost exceeds $1b per year in Australia. The outcome will be a next-generation tool that allows water utilities to move from reactive emergency repairs to proactive repair and predictive replacement. This will enable performance-driven asset management, extending asset life and replacing deteriorated high-risk pipe sections in a timely manner.Read moreRead less
Reducing the Risk of Foundation Failures by Improving the Effectiveness of Geotechnical Investigations. Inadequate geotechnical site investigation is the major factor in construction overruns and delays. In some instances failure may occur. Alternatively, such investigation may result in over-designed foundations. This research will examine these issues through sites, based on numerical simulations of variable soil conditions and investigations. Case studies will be used to verify the modelling. ....Reducing the Risk of Foundation Failures by Improving the Effectiveness of Geotechnical Investigations. Inadequate geotechnical site investigation is the major factor in construction overruns and delays. In some instances failure may occur. Alternatively, such investigation may result in over-designed foundations. This research will examine these issues through sites, based on numerical simulations of variable soil conditions and investigations. Case studies will be used to verify the modelling. A practical framework for planning and implementing geotechnical investigations, based on the variability of the soil profile will be developed. A key aspect of this framework is that, for the first time, site investigations will be linked to risk of foundation failure and cost of overdesign.Read moreRead less