Transport of nucleotide sugars and their roles in cell wall biosynthesis. This project aims to define and manipulate transporters involved in the delivery of activated sugars for cell wall polymer biosynthesis. Cell wall polymers play important structural and functional roles in plants. They also represent an important renewable resource in the form of biomass and contribute to the nutritional value of food. The project will complete the characterisation of cell wall-associated transporters, app ....Transport of nucleotide sugars and their roles in cell wall biosynthesis. This project aims to define and manipulate transporters involved in the delivery of activated sugars for cell wall polymer biosynthesis. Cell wall polymers play important structural and functional roles in plants. They also represent an important renewable resource in the form of biomass and contribute to the nutritional value of food. The project will complete the characterisation of cell wall-associated transporters, apply new technologies to visualise cell wall biosynthesis in growing plants and leverage this knowledge to manipulate biomass in rice. This information will provide fundamental knowledge on a crucial process in plants that can be used the development of functional foods for agriculture and tailored biomass for industry.Read moreRead less
Probing microbial emulsions to break barriers to green oil production. This project aims to understand ultrasonic processing of concentrated slurries of oil-bearing yeast and algae. Humans must reduce their dependency on petroleum. While microorganisms can produce oils as replacement fuels and base chemicals, the processes for extracting these oils are inefficient. Ultrasound could improve oil recovery by replacing toxic solvents. Understanding the effects of ultrasound on microbial emulsions is ....Probing microbial emulsions to break barriers to green oil production. This project aims to understand ultrasonic processing of concentrated slurries of oil-bearing yeast and algae. Humans must reduce their dependency on petroleum. While microorganisms can produce oils as replacement fuels and base chemicals, the processes for extracting these oils are inefficient. Ultrasound could improve oil recovery by replacing toxic solvents. Understanding the effects of ultrasound on microbial emulsions is expected to develop solvent-free oil recovery processes that improve the economic and environmental benefits of microbial oil production. Such processes would greatly increase the efficiency and reduce the cost of producing microbial oils that can be used as green alternatives to petroleum fuels and chemicals.Read moreRead less
Developing eucalypt plantations for pharmaceutical flavanone production. The project aims to produce the tools and knowledge required to establish plantations of mallee eucalypts for the production of pinocembrin and structurally related flavanones. This is important because these flavanones have been shown to have a range of medicinal applications, including treatment of diseases of the central nervous system. The research plans to focus on producing and establishing trees with improved flavano ....Developing eucalypt plantations for pharmaceutical flavanone production. The project aims to produce the tools and knowledge required to establish plantations of mallee eucalypts for the production of pinocembrin and structurally related flavanones. This is important because these flavanones have been shown to have a range of medicinal applications, including treatment of diseases of the central nervous system. The research plans to focus on producing and establishing trees with improved flavanone content and growth rates, and on understanding the biochemical mechanisms that underlie flavanone production and structural modification. Expected outcomes include supporting the development of profitable plantations in rural Australia and the establishment of plantations more widely in southern Australia, especially on marginal land.Read moreRead less
The Permeation of Water through Industrial Membrane Systems. This project aims to understand the permeation of water through commercially relevant non-porous polymeric membranes. Permeation, solubility and diffusivity will be studied in the vicinity of the glass transition temperature to elucidate the changes in free volume that occur through this transition. Non-linear concentration gradients due to anisotropic swelling will be probed using novel laminated membrane systems. Water clustering wil ....The Permeation of Water through Industrial Membrane Systems. This project aims to understand the permeation of water through commercially relevant non-porous polymeric membranes. Permeation, solubility and diffusivity will be studied in the vicinity of the glass transition temperature to elucidate the changes in free volume that occur through this transition. Non-linear concentration gradients due to anisotropic swelling will be probed using novel laminated membrane systems. Water clustering will be evaluated by Fourier transform infrared spectroscopy and nuclear magnetic resonance. Results are proposed to be used to build a new phenomenological model of water permeation that can be used directly by engineers in the design of industrial membrane systems.Read moreRead less
Adding value to blue mallee plantations. The project aims to develop the tools and knowledge required for establishing and enhancing the profitability of plantations of blue mallee (Eucalyptus polybractea). This is important because mallees have considerable potential for sustainable essential oil and biomass production in low rainfall regions, and they can sequester considerable amounts of carbon in their below-ground parts. The project intends to produce trees with improved oil quality and yie ....Adding value to blue mallee plantations. The project aims to develop the tools and knowledge required for establishing and enhancing the profitability of plantations of blue mallee (Eucalyptus polybractea). This is important because mallees have considerable potential for sustainable essential oil and biomass production in low rainfall regions, and they can sequester considerable amounts of carbon in their below-ground parts. The project intends to produce trees with improved oil quality and yields through chromosome doubling and breeding, and to dissect the mechanisms that underpin essential oil production through the production of mutants and studies of the main monoterpene producing enzyme.Read moreRead less
Biosolid flow, separation and activity in anaerobic lagoons. This project aims to develop a fundamental model of the complex, non-steady state flow behaviour in anaerobic lagoons. The project will develop new operating procedures and designs for large municipal, industrial and agricultural anaerobic lagoons. This will improve the efficiency of anaerobic digestion and reduce wastewater treatment costs, as well as increase renewable and sustainable biogas production. The intended outcome is a va ....Biosolid flow, separation and activity in anaerobic lagoons. This project aims to develop a fundamental model of the complex, non-steady state flow behaviour in anaerobic lagoons. The project will develop new operating procedures and designs for large municipal, industrial and agricultural anaerobic lagoons. This will improve the efficiency of anaerobic digestion and reduce wastewater treatment costs, as well as increase renewable and sustainable biogas production. The intended outcome is a validated 3D model that captures the physical and biological complexities of anaerobic lagoons. This will impact the design and operation of partner organisation lagoons, reducing capital and operating costs and improving biogas production.Read moreRead less
Breaking it down: Dissecting the mechanism and exploring new inhibition strategies for polysaccharide cleaving enzymes. Mannose, a common carbohydrate building block, is present in a wide variety of complex polysaccharides including energy storage polymers and glycans attached to proteins. The enzymes that degrade these mannose-rich polymers, termed mannosidases, are important in biofuel production and human health and disease. This project will study a range of mannosidases to chemically and st ....Breaking it down: Dissecting the mechanism and exploring new inhibition strategies for polysaccharide cleaving enzymes. Mannose, a common carbohydrate building block, is present in a wide variety of complex polysaccharides including energy storage polymers and glycans attached to proteins. The enzymes that degrade these mannose-rich polymers, termed mannosidases, are important in biofuel production and human health and disease. This project will study a range of mannosidases to chemically and structurally define their mechanisms and establish strategies to allow intervention in mannosidase-specific disease processes. This work will inform strategies to engineer new enzymes for future biotechnology and industrial applications including sustainable chemical manufacturing, and underpin the development of innovative drugs for treating fungal infections and cancer.Read moreRead less
Making best use of biofuels – understanding the interactions between alcohol and hydrocarbon fuels in engine combustion. Biofuels are increasingly used as blending components for transport fuels. Biofuels possess much different chemical structures from conventional fuels, and can therefore interact with hydrocarbon fuels during engine combustion processes and consequently affect engine efficiency and emissions. This project aims to investigate the chemical interactions between representative com ....Making best use of biofuels – understanding the interactions between alcohol and hydrocarbon fuels in engine combustion. Biofuels are increasingly used as blending components for transport fuels. Biofuels possess much different chemical structures from conventional fuels, and can therefore interact with hydrocarbon fuels during engine combustion processes and consequently affect engine efficiency and emissions. This project aims to investigate the chemical interactions between representative compounds of biofuels (ethanol) and fossil fuels (n-heptane, iso-octane and toluene) during engine autoignition processes. The outcomes will fill a significant gap in our understanding for biofuel combustion chemistry, essential for building predictive combustion models, and will guide the best use of the precious Australian biofuel resources to reduce carbon dioxide emissions. Read moreRead less
Profitable plantations of blue mallee for essential oil production. This project will develop the methods and knowledge required for establishing plantations of eucalypts (blue mallee) with very high and economically viable yields of eucalyptus oil. It is expected that the research will underpin an expansion of the essential oil industry both in Victoria and elsewhere in Australia.
Novel concepts for bioelectrochemical generation of renewable fuels and chemicals from wastewater. Global warming and the diminishing fossil fuel resources are posing an ever increasing threat to our societies and economies. This project aims to develop novel and highly innovative bioelectrochemical processes for the production of valuable fuels and chemicals from wastewater, which is a largely untapped renewable resource.