EnzOnomy - an enzyme-based production pipeline for the bioeconomy. The sustainable production of high value chemicals (e.g. fuels, foods) from renewable materials is a cornerstone for the emerging global bioeconomy. We aim to harness the potential of protein engineering to develop a technology (EnzOnomy) to convert renewable raw material (e.g. sugar) into platform chemicals (e.g. isobutanol, a building block for jet fuels, fibers, plastics and antioxidants). Our multi-disciplinary and well estab ....EnzOnomy - an enzyme-based production pipeline for the bioeconomy. The sustainable production of high value chemicals (e.g. fuels, foods) from renewable materials is a cornerstone for the emerging global bioeconomy. We aim to harness the potential of protein engineering to develop a technology (EnzOnomy) to convert renewable raw material (e.g. sugar) into platform chemicals (e.g. isobutanol, a building block for jet fuels, fibers, plastics and antioxidants). Our multi-disciplinary and well established international team will link scientific progress to markets to enhance potential commercial impact in the bioeconomy. The project thus provides great benefit for our nation as it embeds Australia in technologies and global networks that will cement its leading position to safe-guard the future of our planet.
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Design and engineering of proteins for biotechnology and biomedicine. The primary aim of this application is to enhance the thermodynamic and folding properties of proteins by redesign and engineering. The structures and folding behaviour of the redesigned proteins will be characterised using X-ray crystallography and biophysical techniques. The expected outcomes of this project are: engineering of new proteins that can be used in biotechnology, medical and pharmaceutical applications, or basic ....Design and engineering of proteins for biotechnology and biomedicine. The primary aim of this application is to enhance the thermodynamic and folding properties of proteins by redesign and engineering. The structures and folding behaviour of the redesigned proteins will be characterised using X-ray crystallography and biophysical techniques. The expected outcomes of this project are: engineering of new proteins that can be used in biotechnology, medical and pharmaceutical applications, or basic research; fundamental insights into protein design and engineering; and a wealth of knowledge on the factors that dictate protein stability and folding.Read moreRead less