How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their env ....How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their environment and the evolutionary history of the genes controlling this fundamental process. A major expected outcome is knowledge of the diversity of stomatal opening pathways, which should ultimately lead to improved predictions of plant responses to environmental change and assist future targeted modification of plant growth.Read moreRead less
Managing infectious disease through partial wildlife social networks. This project aims to investigate the dynamics of the spread of infectious disease in wildlife, derived from incomplete information about contact networks. Infectious diseases in wildlife are difficult to track and control, because it is not feasible to monitor each individual in a population and know the contact network for a population. The project will create ways to best utilise incomplete observational data of contact netw ....Managing infectious disease through partial wildlife social networks. This project aims to investigate the dynamics of the spread of infectious disease in wildlife, derived from incomplete information about contact networks. Infectious diseases in wildlife are difficult to track and control, because it is not feasible to monitor each individual in a population and know the contact network for a population. The project will create ways to best utilise incomplete observational data of contact networks to develop robust predictions of disease spread and population fate, and to reliably predict the outcomes of management interventions. These robust prediction methods will provide better insights for conservation of Australian wildlife.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101133
Funder
Australian Research Council
Funding Amount
$427,067.00
Summary
The quick and the dead: identifying mechanisms for plant drought survival. This project aims to identify genes that control plant responses to low air humidity, which enhance drought survival by restricting water loss. Most plant water loss occurs through pores called stomata. This project expects to identify the genes that close stomata within minutes of decreased humidity by determining the molecular changes that occur over this timeframe and testing candidate genes for a critical role. Divers ....The quick and the dead: identifying mechanisms for plant drought survival. This project aims to identify genes that control plant responses to low air humidity, which enhance drought survival by restricting water loss. Most plant water loss occurs through pores called stomata. This project expects to identify the genes that close stomata within minutes of decreased humidity by determining the molecular changes that occur over this timeframe and testing candidate genes for a critical role. Diverse land plant models will be examined to ensure broad applicability of results. A major expected outcome is new knowledge of genes that minimise plant water loss, which would ultimately benefit plant-based industries through new targets for breeding improved, drought-adapted varieties for food security in a drying climate.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL160100131
Funder
Australian Research Council
Funding Amount
$2,496,651.00
Summary
Geoengineering the Southern Ocean? A transdisciplinary assessment. Geoengineering the Southern Ocean? A transdisciplinary assessment. The project aims to comprehensively evaluate the feasibility of offsetting climate change by using geoengineering to boost carbon dioxide removal by Southern Ocean microbes. With existing polar datasets as a platform, the project would combine experiments and modelling to quantify carbon dioxide removal and critically assess the economic feasibility and side effec ....Geoengineering the Southern Ocean? A transdisciplinary assessment. Geoengineering the Southern Ocean? A transdisciplinary assessment. The project aims to comprehensively evaluate the feasibility of offsetting climate change by using geoengineering to boost carbon dioxide removal by Southern Ocean microbes. With existing polar datasets as a platform, the project would combine experiments and modelling to quantify carbon dioxide removal and critically assess the economic feasibility and side effects of geoengineering. Anticipated outcomes include a framework for governance of future research and informed national/international policy on using geoengineering to mitigate climate change.Read moreRead less
Developing a wildlife health intelligence and vaccine distribution system. This project aims to establish an industry-linked pipeline for vaccines to be delivered to animals in edible baits and a near real-time monitoring system for assessing the impact of management actions. This project will develop ultrasensitive diagnostic tests and incorporate biomarkers into baits from Australia's leading pest animal control company. Bait uptake and disease status in the field will be monitored using artif ....Developing a wildlife health intelligence and vaccine distribution system. This project aims to establish an industry-linked pipeline for vaccines to be delivered to animals in edible baits and a near real-time monitoring system for assessing the impact of management actions. This project will develop ultrasensitive diagnostic tests and incorporate biomarkers into baits from Australia's leading pest animal control company. Bait uptake and disease status in the field will be monitored using artificial intelligence technology developed in Tasmania. This integrated wildlife health intelligence and scalable vaccine platform can help protect the iconic Tasmanian devil from disease and increase Australia's preparedness for looming threats to the livestock industry such as African swine fever.Read moreRead less
Contact Networks, Immunity, and Evolution in Competing Cancer Epidemics. The project aims to evaluate evolutionary interactions between two transmissible cancer epidemics affecting Tasmanian devils and quantify their feedback on infection risk and epidemic behaviour. Using contact tracing and a phylogenetic framework we aim to quantify how tumour lineages evolve with each generation of infection and their effects on susceptibility to infection and disease progression. We expect to reveal the hos ....Contact Networks, Immunity, and Evolution in Competing Cancer Epidemics. The project aims to evaluate evolutionary interactions between two transmissible cancer epidemics affecting Tasmanian devils and quantify their feedback on infection risk and epidemic behaviour. Using contact tracing and a phylogenetic framework we aim to quantify how tumour lineages evolve with each generation of infection and their effects on susceptibility to infection and disease progression. We expect to reveal the host immuno-genetic basis underpinning cancer suppression and the adaptive capacity of populations in response to infectious diseases. This should significantly improve our ability to understand and manage this and other epidemic outbreaks in wildlife, as well as advancing our knowledge in cancer ecology and evolution.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100201
Funder
Australian Research Council
Funding Amount
$460,806.00
Summary
Learning how we learn: linking inhibitory brain circuits to motor learning. Understanding the relationship between brain activity and human behaviour is a fundamental question in neuroscience. This project aims to contribute to this question by using cutting-edge brain stimulation techniques to demonstrate causal relationships between inhibitory brain circuit activity and motor learning. This project expects to generate fundamental knowledge about the relationship between the brain and behaviour ....Learning how we learn: linking inhibitory brain circuits to motor learning. Understanding the relationship between brain activity and human behaviour is a fundamental question in neuroscience. This project aims to contribute to this question by using cutting-edge brain stimulation techniques to demonstrate causal relationships between inhibitory brain circuit activity and motor learning. This project expects to generate fundamental knowledge about the relationship between the brain and behaviours. Eventually, this may contribute to the development of optimised training protocols in healthy populations such as school children, recreational and elite athletes, medical and military personnel, and ageing adults, as well as the development of brain stimulation interventions to improve motor learning.Read moreRead less
Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
Development of an amoebic gill disease vaccine to protect Atlantic salmon. This project aims to identify candidate vaccine antigens and produce an experimental vaccine against amoebic gill disease (AGD) that will benefit the Tasmanian and international Atlantic salmon aquaculture industries. AGD is the most significant health problem affecting Atlantic salmon aquaculture in Tasmania. In the last decade, AGD has become a legitimate health threat to the multibillion dollar global Atlantic salmon i ....Development of an amoebic gill disease vaccine to protect Atlantic salmon. This project aims to identify candidate vaccine antigens and produce an experimental vaccine against amoebic gill disease (AGD) that will benefit the Tasmanian and international Atlantic salmon aquaculture industries. AGD is the most significant health problem affecting Atlantic salmon aquaculture in Tasmania. In the last decade, AGD has become a legitimate health threat to the multibillion dollar global Atlantic salmon industry. A solution is needed before AGD fully establishes itself in the largest Atlantic salmon producing nations. The expected outcome of this project is the development of a commercial vaccine that should significantly benefit the Australian and international aquaculture industries. Read moreRead less