Bluebottle dynamics: towards a prediction tool for Surf Life Saving Aust. Many Australians have had a painful bluebottle sting, yet little is known about bluebottles and what brings them to the coast. This project will shed new light on bluebottle dynamics, pathways, and distribution of the beachings. We will use an innovative combination of lab work, ocean surveys, statistical and hydrodynamic modelling to fill knowledge gaps and ultimately provide the framework for prediction.
In partnership w ....Bluebottle dynamics: towards a prediction tool for Surf Life Saving Aust. Many Australians have had a painful bluebottle sting, yet little is known about bluebottles and what brings them to the coast. This project will shed new light on bluebottle dynamics, pathways, and distribution of the beachings. We will use an innovative combination of lab work, ocean surveys, statistical and hydrodynamic modelling to fill knowledge gaps and ultimately provide the framework for prediction.
In partnership with Surf Life Saving Australia (SLSA), we will develop the first bluebottle risk prediction tool for our popular beaches.
Forewarned is forearmed. Forecasts will help mitigate bluebottle stings, lessen their public health burden, while having broad benefits for coastal communities.
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Next-generation ocean current forecasting to improve maritime safety . This project aims to measure upper ocean currents at scales of 10-100 km in Australia's marine estate using pioneering satellite radar technology. The Surface Water and Ocean Topography (SWOT) mission will map currents at 10 times the resolution of present-day satellites and revolutionise our understanding of ocean dynamics. Expected outcomes include validation of SWOT data in Australian waters and merging this data into Bure ....Next-generation ocean current forecasting to improve maritime safety . This project aims to measure upper ocean currents at scales of 10-100 km in Australia's marine estate using pioneering satellite radar technology. The Surface Water and Ocean Topography (SWOT) mission will map currents at 10 times the resolution of present-day satellites and revolutionise our understanding of ocean dynamics. Expected outcomes include validation of SWOT data in Australian waters and merging this data into Bureau of Meteorology ocean models. Downstream benefits include improved ocean forecasts for maritime safety, search-and-rescue, spill modelling, and marine conservation. At the same time, the project will build sovereign capability in emerging remote sensing technology with a legacy beyond the life of the SWOT mission.Read moreRead less
Is there a climatic tipping point for Antarctic Bottom Water formation? Antarctic Bottom Water plays an important role in global ocean circulation and climate and yet its formation is also highly sensitive to climate change. This project will analyse new seafloor, core and water samples from the understudied Cape Darnley, East Antarctica, collected on a voyage in early 2022. This new data will be used in combination with an improved high resolution regional ocean model, to understand modern and ....Is there a climatic tipping point for Antarctic Bottom Water formation? Antarctic Bottom Water plays an important role in global ocean circulation and climate and yet its formation is also highly sensitive to climate change. This project will analyse new seafloor, core and water samples from the understudied Cape Darnley, East Antarctica, collected on a voyage in early 2022. This new data will be used in combination with an improved high resolution regional ocean model, to understand modern and past Antarctic Bottom Water formation under different climate states (warmer and colder than present), to determine if there are climate tipping points for the shut down of Antarctic Bottom Water formation. The anticipated benefits include a better understanding of future climate change on this important water mass.Read moreRead less
ARC Centre of Excellence for Climate Extremes. This Centre aims to transform understanding of past and present climate extremes and revolutionise Australia’s capability to predict them into the future. Climate extremes cost Australia up to $4 billion a year and will intensify over coming decades. This Centre’s blue-sky research will discover processes that explain the behaviour of present and future climate extremes. It will use its researchers, data, modelling, collaboration, graduate programme ....ARC Centre of Excellence for Climate Extremes. This Centre aims to transform understanding of past and present climate extremes and revolutionise Australia’s capability to predict them into the future. Climate extremes cost Australia up to $4 billion a year and will intensify over coming decades. This Centre’s blue-sky research will discover processes that explain the behaviour of present and future climate extremes. It will use its researchers, data, modelling, collaboration, graduate programme and early career researcher mentoring to transform Australia’s capacity to predict climate extremes. This research is expected to make Australia more resilient to climate extremes and minimise risks from climate extremes to the Australian environment, society and economy.Read moreRead less
Untangling the matrix of bacterial biofilms. This research aims to use forefront molecular microbiology and biophysical approaches to advance fundamental knowledge on bacterial biofilms. These bacterial clusters are held together by an extracellular matrix comprised of bacterial-derived fibrous protein and the polysaccharide cellulose, which imparts structural integrity and resistance to antimicrobials. The major goals of this project are to dissect how bacteria regulate production of the biofil ....Untangling the matrix of bacterial biofilms. This research aims to use forefront molecular microbiology and biophysical approaches to advance fundamental knowledge on bacterial biofilms. These bacterial clusters are held together by an extracellular matrix comprised of bacterial-derived fibrous protein and the polysaccharide cellulose, which imparts structural integrity and resistance to antimicrobials. The major goals of this project are to dissect how bacteria regulate production of the biofilm matrix, and examine how changes in the composition of the matrix alters its properties, including the penetration of antimicrobial peptides and antibiotics. The outcomes will help address the economic burden of difficult to treat industrial, environmental and biomedical biofilms.Read moreRead less
Evolutionary models and biodiscovery tools from neurotoxic snake venoms. This project aims to identify the selection pressures that shape snake venom neurotoxins and how they interact with nicotinic acetylcholine receptors, and to elucidate their biodiscovery potential. This project aims to test these important toxins on model systems that represent natural prey items in order to determine the molecular and functional evolution of neurotoxic peptides. Expected outcomes include substantial contri ....Evolutionary models and biodiscovery tools from neurotoxic snake venoms. This project aims to identify the selection pressures that shape snake venom neurotoxins and how they interact with nicotinic acetylcholine receptors, and to elucidate their biodiscovery potential. This project aims to test these important toxins on model systems that represent natural prey items in order to determine the molecular and functional evolution of neurotoxic peptides. Expected outcomes include substantial contributions to the body of evolutionary biology knowledge, while also having the applied benefit of discovering novel compounds with potential for use in drug design and discovery. These outcomes will benefit Australian science and society by elucidating fundamental processes while revealing biodisovery resources.Read moreRead less
Nettles & toxic toupees: the molecular weaponry of venomous caterpillars. This project aims to investigate the structure, function and evolution of peptide toxins in venoms made by caterpillars in superfamily Zygaenoidea. Caterpillars in this group are covered in spines that inject pain-causing venoms, and this protects them from vertebrate and invertebrate predators. This project will test if peptides in this venom cause pain by pharmacological modulation of mammalian ion channels and signallin ....Nettles & toxic toupees: the molecular weaponry of venomous caterpillars. This project aims to investigate the structure, function and evolution of peptide toxins in venoms made by caterpillars in superfamily Zygaenoidea. Caterpillars in this group are covered in spines that inject pain-causing venoms, and this protects them from vertebrate and invertebrate predators. This project will test if peptides in this venom cause pain by pharmacological modulation of mammalian ion channels and signalling receptors, and if they have insecticidal properties. The first three-dimensional structures of caterpillar venom peptides will also be solved. Genomes of representatives of two different zygaenoid families will be produced, and genomic techniques will be used to elucidate how venom use evolved at the molecular level.Read moreRead less
Understanding evolution of dominant bacteria inhabiting the rodent gut . The gut microbiome is central to animal health and immune function, however we have an incomplete understanding of how this important symbiotic ecosystem evolved. By approaching this knowledge gap from a historical perspective and using real-time observation, this project will address how the gut community evolved with the rodent host and how members of that community respond to new selective pressures. The significance of ....Understanding evolution of dominant bacteria inhabiting the rodent gut . The gut microbiome is central to animal health and immune function, however we have an incomplete understanding of how this important symbiotic ecosystem evolved. By approaching this knowledge gap from a historical perspective and using real-time observation, this project will address how the gut community evolved with the rodent host and how members of that community respond to new selective pressures. The significance of these findings is in their capacity to inform our understanding of the relationship between host and microbe, not only within a key model system, but by extrapolation to other host-microbe systems. Read moreRead less
The costs and consequences of resistance to stress in microbial systems. The coexistence of antibiotic resistant and sensitive bacteria in microbial communities represents a paradox. Combining novel ecological models and competition experiments, this project aims to investigate how the pulsing of antibiotics and resources affects the coexistence of resistant and sensitive bacteria. This project expects to generate new knowledge into how the complex non-equilibrium dynamics of natural systems fee ....The costs and consequences of resistance to stress in microbial systems. The coexistence of antibiotic resistant and sensitive bacteria in microbial communities represents a paradox. Combining novel ecological models and competition experiments, this project aims to investigate how the pulsing of antibiotics and resources affects the coexistence of resistant and sensitive bacteria. This project expects to generate new knowledge into how the complex non-equilibrium dynamics of natural systems feeds back to regulate the spread of antibiotic resistance in microbial communities. This should advance our fundamental understanding of microbial competition, and provide a foundation for the development of new ecologically-aware strategies for managing resistance.Read moreRead less