Securing Web-based Services by Policy Coherence and Proof-checking. This project aims to develop a provably correct cybersecurity system for workflows, which enables organizations to provide flexible and more secure web-based services and business communication. The project expects to generate new knowledge, theoretic advancement and result in new technologies in the areas of internet of things and cybersecurity. The expected outcomes include a software tool with documentation, which helps organ ....Securing Web-based Services by Policy Coherence and Proof-checking. This project aims to develop a provably correct cybersecurity system for workflows, which enables organizations to provide flexible and more secure web-based services and business communication. The project expects to generate new knowledge, theoretic advancement and result in new technologies in the areas of internet of things and cybersecurity. The expected outcomes include a software tool with documentation, which helps organisations achieve operational excellence and security, and maintain a trusted environment for end users. This system will provide significant economic and commercial benefits to business and end users with highly secured web-services and improved productivity through a coherent framework and proof-checked workflows.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101344
Funder
Australian Research Council
Funding Amount
$364,981.00
Summary
Advancing genomic-driven infectious diseases modelling. Emerging infectious diseases and antimicrobial resistance are among the greatest threats to Australian health and agriculture, and current surveillance tools may fail to detect and mitigate infectious disease outbreaks in real time. This project will develop advanced phylodynamic methods (i.e., mathematical models of infectious disease transmission and pathogen evolution) to enable real-time surveillance of infectious disease outbreaks as t ....Advancing genomic-driven infectious diseases modelling. Emerging infectious diseases and antimicrobial resistance are among the greatest threats to Australian health and agriculture, and current surveillance tools may fail to detect and mitigate infectious disease outbreaks in real time. This project will develop advanced phylodynamic methods (i.e., mathematical models of infectious disease transmission and pathogen evolution) to enable real-time surveillance of infectious disease outbreaks as they emerge and monitor levels of drug resistance.Read moreRead less
Computational modelling of nanofluids for industrial applications. The use of nanoparticles in heat transfer fluids, then known as nanofluids, increases their specific heat and thermal conductivity. Recent experimental works highlight that anomalous transport phenomena are evident in nanofluids that cannot be adequately described by classical conservation laws. We will extend these conservation laws to incorporate fractional operators to capture the fluid memory effects and the impact of particl ....Computational modelling of nanofluids for industrial applications. The use of nanoparticles in heat transfer fluids, then known as nanofluids, increases their specific heat and thermal conductivity. Recent experimental works highlight that anomalous transport phenomena are evident in nanofluids that cannot be adequately described by classical conservation laws. We will extend these conservation laws to incorporate fractional operators to capture the fluid memory effects and the impact of particle clustering. Computational modelling and experimental investigations will be undertaken to identify the heat transfer mechanisms of various nanofluids. The outcomes of the work will increase knowledge on nanofluids and offer a significant opportunity to improve the efficiency of many thermal engineering systems.Read moreRead less
An evolutionary landscape to better predict our future climate. Soil microbial communities are the most complicated and difficult to study on Earth, but their effects on our climate are profound. This project will examine the evolution of microorganisms and their viruses in soil using novel methods. It will uncover how the evolution of one microbial species influences the evolution of other community members. It will also apply a new model of evolution to the viruses that infect these microorgan ....An evolutionary landscape to better predict our future climate. Soil microbial communities are the most complicated and difficult to study on Earth, but their effects on our climate are profound. This project will examine the evolution of microorganisms and their viruses in soil using novel methods. It will uncover how the evolution of one microbial species influences the evolution of other community members. It will also apply a new model of evolution to the viruses that infect these microorganisms, constructing a viral ‘tree of life’. This improved fundamental understanding of soil communities will be used to study climate feedback from permafrost wetlands, a key and poorly constrained input of global climate models, improving predictions of our future climate.Read moreRead less
Bringing Archaeal biodiversity to life from native Australian herbivores . The aim of this project is to provide deep functional understanding of our recent discovery of novel microbes from the Domain Archaea that inhabit the digestive tracts of native Australian herbivores. These animals are unique natural resources of great cultural, environmental, and economic significance, but increasingly susceptible to habitat change and degradation. Very little is currently known about the microbes that h ....Bringing Archaeal biodiversity to life from native Australian herbivores . The aim of this project is to provide deep functional understanding of our recent discovery of novel microbes from the Domain Archaea that inhabit the digestive tracts of native Australian herbivores. These animals are unique natural resources of great cultural, environmental, and economic significance, but increasingly susceptible to habitat change and degradation. Very little is currently known about the microbes that have co-evolved with these animals, to support their nutrition and health. The project will address these knowledge gaps, and the ensuing discoveries are expected to deliver products and services relevant to environmental health assessment and sustaining the "low methane carbon economy" attributed to these iconic species.Read moreRead less
Ancestral state reconstruction and the evolution of Australian marsupials. This project aims to investigate the diversification and evolvability of Australian marsupials, by enabling genomes, ecology and 3D skeletal shape to synergistically inform evolutionary inference. This project expects to generate new knowledge of the processes that have promoted and maintained marsupial biodiversity, by tracing their evolution across a fossil gap that spans half of their history. Expected outcomes of this ....Ancestral state reconstruction and the evolution of Australian marsupials. This project aims to investigate the diversification and evolvability of Australian marsupials, by enabling genomes, ecology and 3D skeletal shape to synergistically inform evolutionary inference. This project expects to generate new knowledge of the processes that have promoted and maintained marsupial biodiversity, by tracing their evolution across a fossil gap that spans half of their history. Expected outcomes of this project include improved methods for merging fossils into the tree of life and for reconstructing the ecology and morphology of ancestors on phylogenetic trees. This should provide significant benefits, such as a coherent evolutionary context for informing research on marsupial biology, ecology and conservation.Read moreRead less
The culture of implementing Freedom of Information in Australia. In partnership with three Australian Information Commissioners/Ombudsmen this project aims to map the culture of administering Freedom of Information (FOI) laws across a number of Australian jurisdictions. The study aspires to capture and analyse the attitudes among FOI practitioners, government agency managements and political leaders toward information access implementation. The project aims to provide the partner organisations w ....The culture of implementing Freedom of Information in Australia. In partnership with three Australian Information Commissioners/Ombudsmen this project aims to map the culture of administering Freedom of Information (FOI) laws across a number of Australian jurisdictions. The study aspires to capture and analyse the attitudes among FOI practitioners, government agency managements and political leaders toward information access implementation. The project aims to provide the partner organisations with an increased understanding of the culture of administering FOI to inform training/awareness programs and campaigns in order to increase the functionality of FOI. Well-functioning access to information systems is crucial both for good governance and Australia's participation in the digital economy.
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Untangling the matrix of bacterial biofilms. This research aims to use forefront molecular microbiology and biophysical approaches to advance fundamental knowledge on bacterial biofilms. These bacterial clusters are held together by an extracellular matrix comprised of bacterial-derived fibrous protein and the polysaccharide cellulose, which imparts structural integrity and resistance to antimicrobials. The major goals of this project are to dissect how bacteria regulate production of the biofil ....Untangling the matrix of bacterial biofilms. This research aims to use forefront molecular microbiology and biophysical approaches to advance fundamental knowledge on bacterial biofilms. These bacterial clusters are held together by an extracellular matrix comprised of bacterial-derived fibrous protein and the polysaccharide cellulose, which imparts structural integrity and resistance to antimicrobials. The major goals of this project are to dissect how bacteria regulate production of the biofilm matrix, and examine how changes in the composition of the matrix alters its properties, including the penetration of antimicrobial peptides and antibiotics. The outcomes will help address the economic burden of difficult to treat industrial, environmental and biomedical biofilms.Read moreRead less
Evolutionary models and biodiscovery tools from neurotoxic snake venoms. This project aims to identify the selection pressures that shape snake venom neurotoxins and how they interact with nicotinic acetylcholine receptors, and to elucidate their biodiscovery potential. This project aims to test these important toxins on model systems that represent natural prey items in order to determine the molecular and functional evolution of neurotoxic peptides. Expected outcomes include substantial contri ....Evolutionary models and biodiscovery tools from neurotoxic snake venoms. This project aims to identify the selection pressures that shape snake venom neurotoxins and how they interact with nicotinic acetylcholine receptors, and to elucidate their biodiscovery potential. This project aims to test these important toxins on model systems that represent natural prey items in order to determine the molecular and functional evolution of neurotoxic peptides. Expected outcomes include substantial contributions to the body of evolutionary biology knowledge, while also having the applied benefit of discovering novel compounds with potential for use in drug design and discovery. These outcomes will benefit Australian science and society by elucidating fundamental processes while revealing biodisovery resources.Read moreRead less
Transforming tobacco policy to deliver societal benefits. This project aims to develop new regulatory options for tobacco to minimise the legal market while avoiding the adverse societal and economic impacts of transferring consumer demand to illegal tobacco products. It addresses a significant current concern about a growing illegal tobacco market and seeks to improve understanding of the impact of tobacco control policies on the illegal market, and the societal impacts. The project also seeks ....Transforming tobacco policy to deliver societal benefits. This project aims to develop new regulatory options for tobacco to minimise the legal market while avoiding the adverse societal and economic impacts of transferring consumer demand to illegal tobacco products. It addresses a significant current concern about a growing illegal tobacco market and seeks to improve understanding of the impact of tobacco control policies on the illegal market, and the societal impacts. The project also seeks to draw insights from illicit drug policy to understand potential consequences of greater restrictions on the legal tobacco market. The expected outcomes include an enhanced monitoring system for illicit tobacco and policy recommendations to achieve government goals of reducing smoking rates.Read moreRead less