Nonlocal Statistical Mechanics and Logarithmic Conformal Field Theory. Australia has an enviable track record as an innovator and developer of advanced materials. This project in strategic basic research consists of theoretical work within the disciplines of statistical mechanics and conformal field theory to determine the profound role of nonlocal interactions, such as connectivities, in determining the critical physical properties of materials. Connectivities play a significant role in diverse ....Nonlocal Statistical Mechanics and Logarithmic Conformal Field Theory. Australia has an enviable track record as an innovator and developer of advanced materials. This project in strategic basic research consists of theoretical work within the disciplines of statistical mechanics and conformal field theory to determine the profound role of nonlocal interactions, such as connectivities, in determining the critical physical properties of materials. Connectivities play a significant role in diverse applications such as the gelation of polymers, random fuse networks, the spatial spread of epidemics and bushfires and the tertiary recovery of oil. This research will be practically useful in engineering the physical properties of advanced materials such as liquid crystals, gels, polymers and other materials.Read moreRead less
Exact solution of generalized models of polymers and percolation in two dimensions. Originating with the work of Rodney Baxter, Australia is the world leader in exactly solvable lattice models in two dimensions. This project, in strategic basic research, aims to continue this tradition and extend it by solving exactly new classes of two-dimensional lattice models involving nonlocal degrees of freedom. Since this will lead to new universal classes of thermodynamic behaviours for a diverse range o ....Exact solution of generalized models of polymers and percolation in two dimensions. Originating with the work of Rodney Baxter, Australia is the world leader in exactly solvable lattice models in two dimensions. This project, in strategic basic research, aims to continue this tradition and extend it by solving exactly new classes of two-dimensional lattice models involving nonlocal degrees of freedom. Since this will lead to new universal classes of thermodynamic behaviours for a diverse range of polymer-like systems, the potential for exploitation and commercialization is almost limitless. Potential applications include percolation of contaminants through aquifers, the spatial spread of epidemics and bushfires, the tertiary recovery of oil and filtering drinking water.Read moreRead less
Special Research Initiatives - Grant ID: SR0567460
Funder
Australian Research Council
Funding Amount
$85,000.00
Summary
Development of a collaborative environment for high throughput biology discovery pipelines. Modern biological science involves the parallel high-throughput investigation of many hundreds of different experimental targets. Traditional approaches for recording, analysing, mining and cross comparing experimental data are inadequate for conducting high throughput experiments. This proposal aims to develop new algorithms in the high throughput arena that will revolutionize biological discovery.
Digital Imagery for Building 3D City Models. The project will investigate the application of digital photogrammetric imagery, and primarily high-resolution satellite imagery for the creation of visually realistic 3D city models. Virtual reality computer models of urban scenes find application in urban planning, facilities management, engineering and even virtual tourism. Building upon recently initiated collaborative research, the project aims to develop improved methods and procedures for autom ....Digital Imagery for Building 3D City Models. The project will investigate the application of digital photogrammetric imagery, and primarily high-resolution satellite imagery for the creation of visually realistic 3D city models. Virtual reality computer models of urban scenes find application in urban planning, facilities management, engineering and even virtual tourism. Building upon recently initiated collaborative research, the project aims to develop improved methods and procedures for automated, image-based object reconstruction to support the generation of metrically accurate 3D computer models of buildings and the built environment.Read moreRead less
Special Research Initiatives - Grant ID: SR0566602
Funder
Australian Research Council
Funding Amount
$87,933.00
Summary
Development of a collaborative online environment and workbench for the investigation of protein folding. The investigation of protein folding – one the most important unsolved biological problems, is generating large amounts of complex data. This proposal aims to develop a highly collaborative content management system and interactive data mining tools that will allow the open exchange and analysis of protein folding data. A chief goal of this proposal is, by creating a rich informatics envir ....Development of a collaborative online environment and workbench for the investigation of protein folding. The investigation of protein folding – one the most important unsolved biological problems, is generating large amounts of complex data. This proposal aims to develop a highly collaborative content management system and interactive data mining tools that will allow the open exchange and analysis of protein folding data. A chief goal of this proposal is, by creating a rich informatics environment, to foster the exchange of ideas and rapid dissemination of new data across the international array of groups working in parallel on various aspects of the folding problem.Read moreRead less
DNA Dynamics is Shear and Extensional Flows: Simulation and Single Molecule Experiments. The proposal seeks to establish a collaboration between Monash University and Stanford University in order to combine several recent experimental and theoretical advances that have been made by the individual groups in single molecule experimental techniques, extensional rheometry, and molecular rheology, to obtain new insights into the structure and dynamics of biopolymers. The central aim is to make a sign ....DNA Dynamics is Shear and Extensional Flows: Simulation and Single Molecule Experiments. The proposal seeks to establish a collaboration between Monash University and Stanford University in order to combine several recent experimental and theoretical advances that have been made by the individual groups in single molecule experimental techniques, extensional rheometry, and molecular rheology, to obtain new insights into the structure and dynamics of biopolymers. The central aim is to make a significant contribution towards bringing state-of-the-art techniques used for the characterization of polymeric systems to bear on the nature and origin of the elastic properties of biopolymers.Read moreRead less
The flow properties of proteins and other biopolymers. The living cell is an extraordinary organization with a vast variety of biomacromolecules carrying out myriads of functions with great specificity and accuracy. The key issue in cell biology is to unravel the structures of biopolymers and the deep connection that exists between structure and function. This interdisciplinary research program combines recent advances in experimental and theoretical rheology, with advances in protein science, t ....The flow properties of proteins and other biopolymers. The living cell is an extraordinary organization with a vast variety of biomacromolecules carrying out myriads of functions with great specificity and accuracy. The key issue in cell biology is to unravel the structures of biopolymers and the deep connection that exists between structure and function. This interdisciplinary research program combines recent advances in experimental and theoretical rheology, with advances in protein science, to investigate the response of biopolymers to deformation. This approach will lead to insights into the problem of protein folding, the interaction of biopolymers with surfaces, and the physical basis for the mechanical properties of biopolymers.Read moreRead less
Effects of global climate change on marine phytoplankton: interactions between UV radiation and elevated atmospheric carbon dioxide levels. Global climate change is one of the most significant ecological challenges for the 21st Century. Phytoplankton contribute over 45% of the planet's annual net primary production and form the basis of most aquatic food chains. Conversely, some phytoplankton are toxic and cause problems in marine and fresh waters. Climate change can potentially disrupt aquatic ....Effects of global climate change on marine phytoplankton: interactions between UV radiation and elevated atmospheric carbon dioxide levels. Global climate change is one of the most significant ecological challenges for the 21st Century. Phytoplankton contribute over 45% of the planet's annual net primary production and form the basis of most aquatic food chains. Conversely, some phytoplankton are toxic and cause problems in marine and fresh waters. Climate change can potentially disrupt aquatic foodchains by its impact on primary production by phytoplankton or stimulating growth of potentially toxic forms. Our project will investigate the combined impact of increasing carbon dioxide and ultraviolet light on phytoplankton and thereby help climate modellers assess the impact of climate change on aquatic ecosystems and particularly on the nation's and the world's fisheries.Read moreRead less
Allosteric Enhancers: Leads for the Therapy of Cardiovascular Disease. Cardiovascular disease (CVD - heart, stroke and blood vessel disease) kills more people each year than cancer, AIDS and traffic accidents combined. Coronary heart disease (CHD), followed by stroke, is the largest single cause of death in Australia. Allosteric enhancers are particularly attractive drug targets for the prevention of CVD due to their ability to limit injury associated with ischaemic tissue trauma selectively ....Allosteric Enhancers: Leads for the Therapy of Cardiovascular Disease. Cardiovascular disease (CVD - heart, stroke and blood vessel disease) kills more people each year than cancer, AIDS and traffic accidents combined. Coronary heart disease (CHD), followed by stroke, is the largest single cause of death in Australia. Allosteric enhancers are particularly attractive drug targets for the prevention of CVD due to their ability to limit injury associated with ischaemic tissue trauma selectively in tissues where adenosine is elevated. Whilst the development of drugs that protect against heart attack and stroke is a difficult and long term objective, any advances toward this goal would clearly be of great benefit to the community.Read moreRead less
Structure and activity of host-defence peptides from Australian anurans: anticancer agents, neuropeptides and nNOS inhibitors. We have discovered peptides that may have clinical applications. This is significant as these molecules may have one or more of the following properties. They may have anti-cancer effects; they may increase the effectiveness of the immune system by enhancing lymphocyte formation; and, they may act to reduce inflammation, stroke or cardiac conditions by controlling nitri ....Structure and activity of host-defence peptides from Australian anurans: anticancer agents, neuropeptides and nNOS inhibitors. We have discovered peptides that may have clinical applications. This is significant as these molecules may have one or more of the following properties. They may have anti-cancer effects; they may increase the effectiveness of the immune system by enhancing lymphocyte formation; and, they may act to reduce inflammation, stroke or cardiac conditions by controlling nitric oxide formation. Another national benefit is that personnel involved in this project are trained to the highest international standards in peptide chemistry/mass spectrometry/nuclear magnetic resonance: currently, there are not enough trained scientists in this area to meet demand.Read moreRead less