My enemy’s enemy is my friend: The genetics of major plant pathogen killers. Fungi are devastating agents of crop diseases. These plant pathogens, in turn, are often parasitized by other fungi in the field. The project will focus on such interactions between powdery mildews, important pathogens of many crops and wild plants, and their common fungal parasites (Ampelomyces spp.) that have already been utilised as
biocontrol agents in crop protection. Genetic and genomic tools will be used to deter ....My enemy’s enemy is my friend: The genetics of major plant pathogen killers. Fungi are devastating agents of crop diseases. These plant pathogens, in turn, are often parasitized by other fungi in the field. The project will focus on such interactions between powdery mildews, important pathogens of many crops and wild plants, and their common fungal parasites (Ampelomyces spp.) that have already been utilised as
biocontrol agents in crop protection. Genetic and genomic tools will be used to determine if these parasites evolved by switching host from plants to plant pathogens. The project has the potential to make a ground-breaking discovery in this field, and also establish the starting point for new innovative methods to protect a wide diversity
of crops using these fungi or specific compounds derived from them.Read moreRead less
The roles of pathogen effectors in promoting rust diseases of plants. Rust diseases threaten global food security. This cross-institutional project aims to discover how proteins secreted by rust fungi promote disease following their translocation into plant cells. It will use the interaction between flax and the flax rust fungus as a powerful model system to test the hypothesis that manipulation of host RNA metabolism is a fundamental mechanism underpinning rust pathogenesis. This research is in ....The roles of pathogen effectors in promoting rust diseases of plants. Rust diseases threaten global food security. This cross-institutional project aims to discover how proteins secreted by rust fungi promote disease following their translocation into plant cells. It will use the interaction between flax and the flax rust fungus as a powerful model system to test the hypothesis that manipulation of host RNA metabolism is a fundamental mechanism underpinning rust pathogenesis. This research is intended to dramatically improve our understanding of the molecular mechanisms used by rust fungi to establish infection. The knowledge gained is expected to facilitate the development of new strategies for rust disease management in food crops by identifying pathogenic processes that can be targeted for intervention.Read moreRead less
In touch with the environment: dissecting early tactile responses in plants. This project aims to identify the regulatory mechanisms that control touch-responses in plants. Although plants cannot relocate in the face of danger, they are able to sense mechanical manipulations from the environment. These could be caused by pathogens, herbivores, rain or even wind. This touch-responsiveness of plants is essential for pathogen resistance and for triggering architectural changes to overcome obstacles ....In touch with the environment: dissecting early tactile responses in plants. This project aims to identify the regulatory mechanisms that control touch-responses in plants. Although plants cannot relocate in the face of danger, they are able to sense mechanical manipulations from the environment. These could be caused by pathogens, herbivores, rain or even wind. This touch-responsiveness of plants is essential for pathogen resistance and for triggering architectural changes to overcome obstacles and prevent mechanical damage. Using a comprehensive tool set of genetics, genomics and proteomics, this project aims to identify the upstream regulators that control touch responses. Furthermore, it is expected to expand our understanding of the physiological impacts of touch-responses on growth and stress tolerance.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170101165
Funder
Australian Research Council
Funding Amount
$370,808.00
Summary
Molecular interaction between tomato and Fusarium oxysporum. This project aims to develop fungus-resistant crops. Fungal pathogens of crop plants threaten food production food security. The fungus Fusarium oxysporum is the fifth most notorious fungal pathogens of crop plants. This project will use the tomato–Fusarium oxysporum pathosystem to discover how Fusarium manipulates plants to infect them and how plants can resist Fusarium infection. Anticipated outcomes include reduced yield loss in tom ....Molecular interaction between tomato and Fusarium oxysporum. This project aims to develop fungus-resistant crops. Fungal pathogens of crop plants threaten food production food security. The fungus Fusarium oxysporum is the fifth most notorious fungal pathogens of crop plants. This project will use the tomato–Fusarium oxysporum pathosystem to discover how Fusarium manipulates plants to infect them and how plants can resist Fusarium infection. Anticipated outcomes include reduced yield loss in tomato and other crop plants by using genome-editing techniques to develop Fusarium-resistant cultivars.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100151
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Enhancing resistance to wheat stripe rust disease. This project aims to investigate why wheat succumbs to stripe rust fungus, a grave threat to global wheat production. Wheat is the primary agricultural and revenue crop of Australia, cultivated since early European settlement. Severe disease epidemics arise when the fast evolving rust pathogen breaks down host plant genetic resistance. This project will investigate the molecular mechanisms of host-pathogen recognition and the consequences of pat ....Enhancing resistance to wheat stripe rust disease. This project aims to investigate why wheat succumbs to stripe rust fungus, a grave threat to global wheat production. Wheat is the primary agricultural and revenue crop of Australia, cultivated since early European settlement. Severe disease epidemics arise when the fast evolving rust pathogen breaks down host plant genetic resistance. This project will investigate the molecular mechanisms of host-pathogen recognition and the consequences of pathogen variation to determine the causes of resistance breakdown. The expected outcome is robust rust-resistant wheat cultivars to maintain global food security.Read moreRead less
Putting new herbicide targets on the table. This project aims to discover plant processes and plant proteins that can be the target for new herbicides. Australia's food security is being threatened by a rise in resistance to herbicides, the chemicals relied on to control weeds. In over 20 years a truly new herbicide has not appeared. This project aims to provide validated new targets to engage agrochemical industry and accelerate the rate farmers get tools to manage problematic weeds, the major ....Putting new herbicide targets on the table. This project aims to discover plant processes and plant proteins that can be the target for new herbicides. Australia's food security is being threatened by a rise in resistance to herbicides, the chemicals relied on to control weeds. In over 20 years a truly new herbicide has not appeared. This project aims to provide validated new targets to engage agrochemical industry and accelerate the rate farmers get tools to manage problematic weeds, the major yield penalty for both developed and developing world agriculture. The project expects enable effective collaboration with industry to develop new herbicides.Read moreRead less
Molecular basis for susceptibility and immunity to Fusarium wilt disease. Fusarium wilt is a devastating disease of many important crop plants, including banana, cotton and tomato. There are significant gaps in our understanding of this disease that need to be addressed to enable better disease management. This project aims to identify and analyse tomato proteins targeted by Fusarium effector proteins (virulence factors), determine how corresponding tomato receptors (resistance proteins) recogni ....Molecular basis for susceptibility and immunity to Fusarium wilt disease. Fusarium wilt is a devastating disease of many important crop plants, including banana, cotton and tomato. There are significant gaps in our understanding of this disease that need to be addressed to enable better disease management. This project aims to identify and analyse tomato proteins targeted by Fusarium effector proteins (virulence factors), determine how corresponding tomato receptors (resistance proteins) recognise these effectors, and identify the signalling pathways and critical defence responses activated by these receptors. The intention is to close the gaps in our understanding and use the knowledge gained to develop new strategies for disease control by interfering with fungal pathogenicity and enhancing plant resistance.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100806
Funder
Australian Research Council
Funding Amount
$419,854.00
Summary
Towards herbicide cocktails with a new mode of action to avert resistance. This project aims to target herbicide resistant weeds which represent one of the largest threats to Australian and global food security. Targeting of unexplored pathways in plants to develop a novel herbicide strategy is expected to be achieved, and will include the structural and functional characterisation of key enzymes in these pathways. This project is expected to provide significant benefits for effective weed manag ....Towards herbicide cocktails with a new mode of action to avert resistance. This project aims to target herbicide resistant weeds which represent one of the largest threats to Australian and global food security. Targeting of unexplored pathways in plants to develop a novel herbicide strategy is expected to be achieved, and will include the structural and functional characterisation of key enzymes in these pathways. This project is expected to provide significant benefits for effective weed management to sustain Australia’s agricultural industry through enhanced food production from increased crop yields, whilst ensuring food security. These outcomes, coupled with decades of over-reliance on current herbicides, means there has never been a greater need for new and effective herbicides.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101560
Funder
Australian Research Council
Funding Amount
$419,589.00
Summary
Towards understanding the molecular details of canola-infection by Fusarium. This project aims at improving our understanding of how canola plants are infected by the pathogenic fungus Fusarium oxysporum. Canola is the primary oilseed crop, and the overall third most important crop in Australia, accounting for a 3 billion AUS$ industry. Fusarium is a relatively new fungal disease to Australian canola, but projected to become a serious threat in the future. The project will provide insights into ....Towards understanding the molecular details of canola-infection by Fusarium. This project aims at improving our understanding of how canola plants are infected by the pathogenic fungus Fusarium oxysporum. Canola is the primary oilseed crop, and the overall third most important crop in Australia, accounting for a 3 billion AUS$ industry. Fusarium is a relatively new fungal disease to Australian canola, but projected to become a serious threat in the future. The project will provide insights into the earliest stages of plant-infection by the fungus on a cellular level, using molecular biology, genetics and microscopic tools. Expected outcomes of this research include the identification of key components to improve plant defense against Fusarium, and the development of strategies to improve the plant's resilience.Read moreRead less
The Potential of the Fungicide Phosphite to Control the Autonomous Spread of Phytophthora cinnamomi in Natural and Rehabilitated Ecosystems. Phytophthora cinnamomi is recognised by the Federal Government as a key threatening process to Australia's biodiversity. This project will enhance the existing methodologies and protocols to improve the effectiveness and persistence of phosphite to reduce or contain the autonomous spread of this pathogen through susceptible and threatened plant communities. ....The Potential of the Fungicide Phosphite to Control the Autonomous Spread of Phytophthora cinnamomi in Natural and Rehabilitated Ecosystems. Phytophthora cinnamomi is recognised by the Federal Government as a key threatening process to Australia's biodiversity. This project will enhance the existing methodologies and protocols to improve the effectiveness and persistence of phosphite to reduce or contain the autonomous spread of this pathogen through susceptible and threatened plant communities. It will provide environmental, mining and land-care organisations with improved techniques to control P. cinnamomi in a range of plant communities and environments associated with mining and natural ecosystems.Read moreRead less